ZSC25.H14INVITRO.0.PSG.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ZSC25.H14INVITRO.0.PSG.A
Gene (human)	ZSCAN25 (GeneCards)
Gene synonyms (human)	ZNF498
Gene (mouse)
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	A

Motif length	15
Consensus	nhhdCACCCCTRChn
GC content	58.94%
Information content (bits; total / per base)	13.898 / 0.927
Data sources	ChIP-Seq + HT-SELEX + Genomic HT-SELEX
Aligned words	7563
Previous names

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	Centrality, median	Centrality, best
Overall	3 (3)	0.865	0.869	0.738	0.744	0.711	0.711	31.824	52.456

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
overall, 2 experiments	median	0.858	0.866	0.65	0.689	0.557	0.602
overall, 2 experiments	best	0.907	0.914	0.677	0.718	0.57	0.619
Lysate, 1 experiments	median	0.907	0.914	0.677	0.718	0.57	0.619
Lysate, 1 experiments	best	0.907	0.914	0.677	0.718	0.57	0.619
IVT, 1 experiments	median	0.809	0.818	0.623	0.66	0.544	0.585
IVT, 1 experiments	best	0.809	0.818	0.623	0.66	0.544	0.585

Genomic HT-SELEX benchmarking		Centrality	pseudo-auROC	auROC	auPR
overall, 2 experiments	median	308.607	0.897	0.894	0.783
overall, 2 experiments	best	614.444	0.93	0.955	0.909
Lysate, 1 experiments	median	614.444	0.93	0.955	0.909
Lysate, 1 experiments	best	614.444	0.93	0.955	0.909
IVT, 1 experiments	median	2.77	0.864	0.832	0.657
IVT, 1 experiments	best	2.77	0.864	0.832	0.657

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	More than 3 adjacent zinc fingers {2.3.3} (TFClass)
TF subfamily	Unclassified {2.3.3.0} (TFClass)
TFClass ID	TFClass: 2.3.3.0.42
HGNC	HGNC:21961
MGI
EntrezGene (human)	GeneID:221785 (SSTAR profile)
EntrezGene (mouse)
UniProt ID (human)	ZSC25_HUMAN
UniProt ID (mouse)
UniProt AC (human)	Q6NSZ9 (TFClass)
UniProt AC (mouse)
GRECO-DB-TF	yes

ChIP-Seq	3 human, 0 mouse
HT-SELEX	2 overall: 1 Lysate, 1 IVT, 0 GFPIVT
Genomic HT-SELEX	2 overall: 1 Lysate, 1 IVT, 0 GFPIVT
SMiLE-Seq	0
PBM	0

PCM	ZSC25.H14INVITRO.0.PSG.A.pcm
PWM	ZSC25.H14INVITRO.0.PSG.A.pwm
PFM	ZSC25.H14INVITRO.0.PSG.A.pfm
Threshold to P-value map	ZSC25.H14INVITRO.0.PSG.A.thr
Motif in other formats
JASPAR format	ZSC25.H14INVITRO.0.PSG.A_jaspar_format.txt
MEME format	ZSC25.H14INVITRO.0.PSG.A_meme_format.meme
Transfac format	ZSC25.H14INVITRO.0.PSG.A_transfac_format.txt
Homer format	ZSC25.H14INVITRO.0.PSG.A_homer_format_0.001.txt ZSC25.H14INVITRO.0.PSG.A_homer_format_0.0005.txt ZSC25.H14INVITRO.0.PSG.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	1651.0	1312.0	2607.0	1993.0
02	3186.0	2621.0	583.0	1173.0
03	763.0	3107.0	466.0	3227.0
04	1104.0	824.0	1694.0	3941.0
05	292.0	6663.0	156.0	452.0
06	6302.0	585.0	176.0	500.0
07	232.0	6751.0	106.0	474.0
08	25.0	7481.0	28.0	29.0
09	5.0	7334.0	14.0	210.0
10	34.0	7353.0	25.0	151.0
11	49.0	62.0	45.0	7407.0
12	1527.0	401.0	5071.0	564.0
13	190.0	5943.0	166.0	1264.0
14	3366.5	1325.5	1025.5	1845.5
15	1984.0	1880.0	1057.0	2642.0

PFM

	A	C	G	T
01	0.218	0.173	0.345	0.264
02	0.421	0.347	0.077	0.155
03	0.101	0.411	0.062	0.427
04	0.146	0.109	0.224	0.521
05	0.039	0.881	0.021	0.06
06	0.833	0.077	0.023	0.066
07	0.031	0.893	0.014	0.063
08	0.003	0.989	0.004	0.004
09	0.001	0.97	0.002	0.028
10	0.004	0.972	0.003	0.02
11	0.006	0.008	0.006	0.979
12	0.202	0.053	0.671	0.075
13	0.025	0.786	0.022	0.167
14	0.445	0.175	0.136	0.244
15	0.262	0.249	0.14	0.349

PWM

	A	C	G	T
01	-0.135	-0.365	0.321	0.053
02	0.521	0.326	-1.174	-0.477
03	-0.906	0.496	-1.397	0.534
04	-0.537	-0.829	-0.11	0.734
05	-1.862	1.259	-2.482	-1.427
06	1.203	-1.17	-2.363	-1.327
07	-2.09	1.272	-2.862	-1.38
08	-4.241	1.375	-4.137	-4.104
09	-5.567	1.355	-4.759	-2.188
10	-3.956	1.357	-4.241	-2.514
11	-3.61	-3.383	-3.691	1.365
12	-0.213	-1.546	0.986	-1.207
13	-2.287	1.144	-2.421	-0.402
14	0.576	-0.355	-0.611	-0.024
15	0.048	-0.006	-0.581	0.334

Standard thresholds

P-value	Threshold
0.001	3.24191
0.0005	4.40946
0.0001	6.81666