ZSC25.H14CORE.0.PSG.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ZSC25.H14CORE.0.PSG.A
Gene (human)	ZSCAN25 (GeneCards)
Gene synonyms (human)	ZNF498
Gene (mouse)
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	A

Motif length	21
Consensus	bYhbvbhbMCYCACCCCTRCM
GC content	64.98%
Information content (bits; total / per base)	19.469 / 0.927
Data sources	ChIP-Seq + HT-SELEX + Genomic HT-SELEX
Aligned words	995
Previous names

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	Centrality, median	Centrality, best
Overall	3 (3)	0.887	0.888	0.77	0.777	0.795	0.797	46.854	59.886

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
overall, 2 experiments	median	0.845	0.852	0.639	0.68	0.551	0.595
overall, 2 experiments	best	0.895	0.901	0.666	0.709	0.564	0.613
Lysate, 1 experiments	median	0.895	0.901	0.666	0.709	0.564	0.613
Lysate, 1 experiments	best	0.895	0.901	0.666	0.709	0.564	0.613
IVT, 1 experiments	median	0.795	0.803	0.611	0.65	0.537	0.578
IVT, 1 experiments	best	0.795	0.803	0.611	0.65	0.537	0.578

Genomic HT-SELEX benchmarking		Centrality	pseudo-auROC	auROC	auPR
overall, 2 experiments	median	293.545	0.95	0.904	0.799
overall, 2 experiments	best	584.432	0.962	0.957	0.904
Lysate, 1 experiments	median	584.432	0.962	0.957	0.904
Lysate, 1 experiments	best	584.432	0.962	0.957	0.904
IVT, 1 experiments	median	2.658	0.937	0.851	0.693
IVT, 1 experiments	best	2.658	0.937	0.851	0.693

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	More than 3 adjacent zinc fingers {2.3.3} (TFClass)
TF subfamily	Unclassified {2.3.3.0} (TFClass)
TFClass ID	TFClass: 2.3.3.0.42
HGNC	HGNC:21961
MGI
EntrezGene (human)	GeneID:221785 (SSTAR profile)
EntrezGene (mouse)
UniProt ID (human)	ZSC25_HUMAN
UniProt ID (mouse)
UniProt AC (human)	Q6NSZ9 (TFClass)
UniProt AC (mouse)
GRECO-DB-TF	yes

ChIP-Seq	3 human, 0 mouse
HT-SELEX	2 overall: 1 Lysate, 1 IVT, 0 GFPIVT
Genomic HT-SELEX	2 overall: 1 Lysate, 1 IVT, 0 GFPIVT
SMiLE-Seq	0
PBM	0

PCM	ZSC25.H14CORE.0.PSG.A.pcm
PWM	ZSC25.H14CORE.0.PSG.A.pwm
PFM	ZSC25.H14CORE.0.PSG.A.pfm
Threshold to P-value map	ZSC25.H14CORE.0.PSG.A.thr
Motif in other formats
JASPAR format	ZSC25.H14CORE.0.PSG.A_jaspar_format.txt
MEME format	ZSC25.H14CORE.0.PSG.A_meme_format.meme
Transfac format	ZSC25.H14CORE.0.PSG.A_transfac_format.txt
Homer format	ZSC25.H14CORE.0.PSG.A_homer_format_0.001.txt ZSC25.H14CORE.0.PSG.A_homer_format_0.0005.txt ZSC25.H14CORE.0.PSG.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	119.0	481.0	183.0	212.0
02	74.0	632.0	99.0	190.0
03	152.0	400.0	150.0	293.0
04	71.0	472.0	132.0	320.0
05	147.0	554.0	152.0	142.0
06	121.0	480.0	168.0	226.0
07	149.0	415.0	101.0	330.0
08	126.0	311.0	345.0	213.0
09	280.0	666.0	10.0	39.0
10	10.0	768.0	10.0	207.0
11	88.0	114.0	69.0	724.0
12	0.0	986.0	0.0	9.0
13	825.0	43.0	5.0	122.0
14	13.0	916.0	17.0	49.0
15	5.0	981.0	4.0	5.0
16	1.0	936.0	1.0	57.0
17	0.0	993.0	0.0	2.0
18	2.0	0.0	0.0	993.0
19	78.0	61.0	793.0	63.0
20	2.0	833.0	1.0	159.0
21	542.0	272.0	24.0	157.0

PFM

	A	C	G	T
01	0.12	0.483	0.184	0.213
02	0.074	0.635	0.099	0.191
03	0.153	0.402	0.151	0.294
04	0.071	0.474	0.133	0.322
05	0.148	0.557	0.153	0.143
06	0.122	0.482	0.169	0.227
07	0.15	0.417	0.102	0.332
08	0.127	0.313	0.347	0.214
09	0.281	0.669	0.01	0.039
10	0.01	0.772	0.01	0.208
11	0.088	0.115	0.069	0.728
12	0.0	0.991	0.0	0.009
13	0.829	0.043	0.005	0.123
14	0.013	0.921	0.017	0.049
15	0.005	0.986	0.004	0.005
16	0.001	0.941	0.001	0.057
17	0.0	0.998	0.0	0.002
18	0.002	0.0	0.0	0.998
19	0.078	0.061	0.797	0.063
20	0.002	0.837	0.001	0.16
21	0.545	0.273	0.024	0.158

PWM

	A	C	G	T
01	-0.73	0.656	-0.304	-0.159
02	-1.196	0.928	-0.911	-0.267
03	-0.488	0.472	-0.501	0.163
04	-1.237	0.637	-0.628	0.25
05	-0.521	0.797	-0.488	-0.555
06	-0.713	0.654	-0.389	-0.095
07	-0.508	0.509	-0.891	0.281
08	-0.673	0.222	0.325	-0.154
09	0.118	0.981	-3.062	-1.817
10	-3.062	1.123	-3.062	-0.182
11	-1.027	-0.772	-1.265	1.064
12	-4.978	1.372	-4.978	-3.151
13	1.194	-1.723	-3.617	-0.705
14	-2.834	1.299	-2.593	-1.597
15	-3.617	1.367	-3.778	-3.617
16	-4.521	1.32	-4.521	-1.45
17	-4.978	1.379	-4.978	-4.208
18	-4.208	-4.978	-4.978	1.379
19	-1.145	-1.385	1.155	-1.353
20	-4.208	1.204	-4.521	-0.444
21	0.775	0.089	-2.276	-0.456

Standard thresholds

P-value	Threshold
0.001	0.19481
0.0005	1.69946
0.0001	4.85441