ZN728.H14INVIVO.0.PSG.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ZN728.H14INVIVO.0.PSG.A
Gene (human)	ZNF728 (GeneCards)
Gene synonyms (human)
Gene (mouse)	Znf728
Gene synonyms (mouse)	Zfp458
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	A

Motif length	19
Consensus	MCYRKdMCCAGChdMhdYh
GC content	59.52%
Information content (bits; total / per base)	14.64 / 0.771
Data sources	ChIP-Seq + HT-SELEX + Genomic HT-SELEX
Aligned words	924
Previous names

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	Centrality, median	Centrality, best
Overall	2 (2)	0.919	0.952	0.9	0.946	0.838	0.94	118.702	150.444

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
GFPIVT, 2 experiments	median	0.586	0.589	0.533	0.545	0.508	0.522
GFPIVT, 2 experiments	best	0.613	0.617	0.54	0.557	0.508	0.528

Genomic HT-SELEX benchmarking		Centrality	pseudo-auROC	auROC	auPR
GFPIVT, 2 experiments	median	97.37	0.817	0.839	0.815
GFPIVT, 2 experiments	best	274.081	0.886	0.914	0.895

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	More than 3 adjacent zinc fingers {2.3.3} (TFClass)
TF subfamily	Unclassified {2.3.3.0} (TFClass)
TFClass ID	TFClass: 2.3.3.0.238
HGNC	HGNC:32463
MGI	MGI:3040691
EntrezGene (human)	GeneID:388523 (SSTAR profile)
EntrezGene (mouse)	GeneID:238690 (SSTAR profile)
UniProt ID (human)	ZN728_HUMAN
UniProt ID (mouse)	ZN728_MOUSE
UniProt AC (human)	P0DKX0 (TFClass)
UniProt AC (mouse)	Q6P5C7 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	2 human, 0 mouse
HT-SELEX	2 overall: 0 Lysate, 0 IVT, 2 GFPIVT
Genomic HT-SELEX	2 overall: 0 Lysate, 0 IVT, 2 GFPIVT
SMiLE-Seq	0
PBM	0

PCM	ZN728.H14INVIVO.0.PSG.A.pcm
PWM	ZN728.H14INVIVO.0.PSG.A.pwm
PFM	ZN728.H14INVIVO.0.PSG.A.pfm
Threshold to P-value map	ZN728.H14INVIVO.0.PSG.A.thr
Motif in other formats
JASPAR format	ZN728.H14INVIVO.0.PSG.A_jaspar_format.txt
MEME format	ZN728.H14INVIVO.0.PSG.A_meme_format.meme
Transfac format	ZN728.H14INVIVO.0.PSG.A_transfac_format.txt
Homer format	ZN728.H14INVIVO.0.PSG.A_homer_format_0.001.txt ZN728.H14INVIVO.0.PSG.A_homer_format_0.0005.txt ZN728.H14INVIVO.0.PSG.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	540.0	299.0	29.0	56.0
02	10.0	818.0	66.0	30.0
03	111.0	214.0	25.0	574.0
04	145.0	36.0	709.0	34.0
05	24.0	63.0	503.0	334.0
06	413.0	106.0	209.0	196.0
07	432.0	394.0	39.0	59.0
08	25.0	777.0	25.0	97.0
09	34.0	863.0	14.0	13.0
10	841.0	20.0	39.0	24.0
11	12.0	19.0	890.0	3.0
12	37.0	826.0	21.0	40.0
13	159.0	246.0	48.0	471.0
14	116.0	69.0	421.0	318.0
15	78.0	697.0	73.0	76.0
16	120.0	253.0	85.0	466.0
17	184.0	113.0	479.0	148.0
18	68.0	604.0	96.0	156.0
19	311.0	150.0	111.0	352.0

PFM

	A	C	G	T
01	0.584	0.324	0.031	0.061
02	0.011	0.885	0.071	0.032
03	0.12	0.232	0.027	0.621
04	0.157	0.039	0.767	0.037
05	0.026	0.068	0.544	0.361
06	0.447	0.115	0.226	0.212
07	0.468	0.426	0.042	0.064
08	0.027	0.841	0.027	0.105
09	0.037	0.934	0.015	0.014
10	0.91	0.022	0.042	0.026
11	0.013	0.021	0.963	0.003
12	0.04	0.894	0.023	0.043
13	0.172	0.266	0.052	0.51
14	0.126	0.075	0.456	0.344
15	0.084	0.754	0.079	0.082
16	0.13	0.274	0.092	0.504
17	0.199	0.122	0.518	0.16
18	0.074	0.654	0.104	0.169
19	0.337	0.162	0.12	0.381

PWM

	A	C	G	T
01	0.845	0.256	-2.025	-1.394
02	-2.99	1.259	-1.235	-1.993
03	-0.725	-0.076	-2.165	0.906
04	-0.461	-1.82	1.116	-1.874
05	-2.203	-1.28	0.774	0.366
06	0.578	-0.77	-0.099	-0.163
07	0.623	0.531	-1.743	-1.344
08	-2.165	1.208	-2.165	-0.858
09	-1.874	1.313	-2.696	-2.761
10	1.287	-2.372	-1.743	-2.203
11	-2.832	-2.419	1.343	-3.901
12	-1.794	1.269	-2.327	-1.719
13	-0.37	0.062	-1.544	0.709
14	-0.682	-1.191	0.597	0.318
15	-1.071	1.099	-1.136	-1.097
16	-0.648	0.09	-0.987	0.698
17	-0.226	-0.707	0.725	-0.441
18	-1.205	0.957	-0.868	-0.389
19	0.295	-0.428	-0.725	0.419

Standard thresholds

P-value	Threshold
0.001	3.43161
0.0005	4.47181
0.0001	6.66981