ZN721.H14INVIVO.0.PSG.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ZN721.H14INVIVO.0.PSG.A
Gene (human)	ZNF721 (GeneCards)
Gene synonyms (human)	KIAA1982
Gene (mouse)
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	A

Motif length	17
Consensus	vRRAAARMAGMhvhMYY
GC content	42.12%
Information content (bits; total / per base)	14.995 / 0.882
Data sources	ChIP-Seq + HT-SELEX + Genomic HT-SELEX
Aligned words	406
Previous names

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	Centrality, median	Centrality, best
Overall	4 (4)	0.859	0.881	0.791	0.823	0.86	0.893	112.888	129.155

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
GFPIVT, 3 experiments	median	0.983	0.97	0.919	0.908	0.776	0.785
GFPIVT, 3 experiments	best	0.986	0.982	0.975	0.959	0.95	0.93

Genomic HT-SELEX benchmarking		Centrality	pseudo-auROC	auROC	auPR
GFPIVT, 3 experiments	median	174.959	0.786	0.756	0.592
GFPIVT, 3 experiments	best	738.824	0.881	0.861	0.819

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	More than 3 adjacent zinc fingers {2.3.3} (TFClass)
TF subfamily	ZNF595-like {2.3.3.77} (TFClass)
TFClass ID	TFClass: 2.3.3.77.2
HGNC	HGNC:29425
MGI
EntrezGene (human)	GeneID:170960 (SSTAR profile)
EntrezGene (mouse)
UniProt ID (human)	ZN721_HUMAN
UniProt ID (mouse)
UniProt AC (human)	Q8TF20 (TFClass)
UniProt AC (mouse)
GRECO-DB-TF	yes

ChIP-Seq	4 human, 0 mouse
HT-SELEX	3 overall: 0 Lysate, 0 IVT, 3 GFPIVT
Genomic HT-SELEX	3 overall: 0 Lysate, 0 IVT, 3 GFPIVT
SMiLE-Seq	0
PBM	0

PCM	ZN721.H14INVIVO.0.PSG.A.pcm
PWM	ZN721.H14INVIVO.0.PSG.A.pwm
PFM	ZN721.H14INVIVO.0.PSG.A.pfm
Threshold to P-value map	ZN721.H14INVIVO.0.PSG.A.thr
Motif in other formats
JASPAR format	ZN721.H14INVIVO.0.PSG.A_jaspar_format.txt
MEME format	ZN721.H14INVIVO.0.PSG.A_meme_format.meme
Transfac format	ZN721.H14INVIVO.0.PSG.A_transfac_format.txt
Homer format	ZN721.H14INVIVO.0.PSG.A_homer_format_0.001.txt ZN721.H14INVIVO.0.PSG.A_homer_format_0.0005.txt ZN721.H14INVIVO.0.PSG.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	229.0	67.0	61.0	49.0
02	246.0	4.0	114.0	42.0
03	180.0	10.0	202.0	14.0
04	332.0	24.0	32.0	18.0
05	386.0	4.0	16.0	0.0
06	394.0	0.0	0.0	12.0
07	289.0	15.0	100.0	2.0
08	298.0	71.0	29.0	8.0
09	389.0	0.0	17.0	0.0
10	11.0	2.0	391.0	2.0
11	47.0	321.0	24.0	14.0
12	138.0	48.0	47.0	173.0
13	64.0	116.0	167.0	59.0
14	71.0	169.0	14.0	152.0
15	84.0	234.0	18.0	70.0
16	16.0	286.0	11.0	93.0
17	26.0	269.0	24.0	87.0

PFM

	A	C	G	T
01	0.564	0.165	0.15	0.121
02	0.606	0.01	0.281	0.103
03	0.443	0.025	0.498	0.034
04	0.818	0.059	0.079	0.044
05	0.951	0.01	0.039	0.0
06	0.97	0.0	0.0	0.03
07	0.712	0.037	0.246	0.005
08	0.734	0.175	0.071	0.02
09	0.958	0.0	0.042	0.0
10	0.027	0.005	0.963	0.005
11	0.116	0.791	0.059	0.034
12	0.34	0.118	0.116	0.426
13	0.158	0.286	0.411	0.145
14	0.175	0.416	0.034	0.374
15	0.207	0.576	0.044	0.172
16	0.039	0.704	0.027	0.229
17	0.064	0.663	0.059	0.214

PWM

	A	C	G	T
01	0.806	-0.408	-0.5	-0.713
02	0.877	-2.93	0.115	-0.862
03	0.567	-2.192	0.681	-1.894
04	1.175	-1.396	-1.123	-1.664
05	1.325	-2.93	-1.772	-4.228
06	1.345	-4.228	-4.228	-2.032
07	1.037	-1.831	-0.015	-3.382
08	1.067	-0.351	-1.217	-2.383
09	1.333	-4.228	-1.717	-4.228
10	-2.109	-3.382	1.338	-3.382
11	-0.753	1.141	-1.396	-1.894
12	0.303	-0.733	-0.753	0.527
13	-0.453	0.132	0.492	-0.532
14	-0.351	0.504	-1.894	0.399
15	-0.186	0.827	-1.664	-0.365
16	-1.772	1.026	-2.109	-0.086
17	-1.321	0.966	-1.396	-0.152

Standard thresholds

P-value	Threshold
0.001	3.24826
0.0005	4.36291
0.0001	6.68401