ZN648.H14RSNP.0.PSGI.D motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ZN648.H14RSNP.0.PSGI.D
Gene (human)	ZNF648 (GeneCards)
Gene synonyms (human)
Gene (mouse)
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	D

Motif length	26
Consensus	RYCAGCGYnvbhhhnnnbYYCCCYYh
GC content	63.15%
Information content (bits; total / per base)	20.165 / 0.776
Data sources	ChIP-Seq + HT-SELEX + Genomic HT-SELEX + SMiLe-Seq
Aligned words	893
Previous names

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	Centrality, median	Centrality, best
Overall	2 (2)	0.742	0.782	0.591	0.65	0.682	0.73	25.741	42.481

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
GFPIVT, 1 experiments	median	0.999	0.998	0.997	0.996	0.978	0.974
GFPIVT, 1 experiments	best	0.999	0.998	0.997	0.996	0.978	0.974

Genomic HT-SELEX benchmarking		Centrality	pseudo-auROC	auROC	auPR
overall, 2 experiments	median	150.554	0.771	0.787	0.69
overall, 2 experiments	best	507.347	0.837	0.866	0.778
Lysate, 1 experiments	median	116.638	0.764	0.775	0.68
Lysate, 1 experiments	best	161.469	0.777	0.782	0.699
GFPIVT, 1 experiments	median	354.495	0.797	0.855	0.769
GFPIVT, 1 experiments	best	507.347	0.837	0.866	0.778

SMiLE-Seq benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 2 experiments	median	0.919	0.892	0.837	0.816	0.747	0.74
Overall, 2 experiments	best	0.968	0.949	0.938	0.912	0.867	0.842

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	More than 3 adjacent zinc fingers {2.3.3} (TFClass)
TF subfamily	Unclassified {2.3.3.0} (TFClass)
TFClass ID	TFClass: 2.3.3.0.94
HGNC	HGNC:18190
MGI
EntrezGene (human)	GeneID:127665 (SSTAR profile)
EntrezGene (mouse)
UniProt ID (human)	ZN648_HUMAN
UniProt ID (mouse)
UniProt AC (human)	Q5T619 (TFClass)
UniProt AC (mouse)
GRECO-DB-TF	yes

ChIP-Seq	2 human, 0 mouse
HT-SELEX	1 overall: 0 Lysate, 0 IVT, 1 GFPIVT
Genomic HT-SELEX	2 overall: 1 Lysate, 0 IVT, 1 GFPIVT
SMiLE-Seq	2
PBM	0

PCM	ZN648.H14RSNP.0.PSGI.D.pcm
PWM	ZN648.H14RSNP.0.PSGI.D.pwm
PFM	ZN648.H14RSNP.0.PSGI.D.pfm
Threshold to P-value map	ZN648.H14RSNP.0.PSGI.D.thr
Motif in other formats
JASPAR format	ZN648.H14RSNP.0.PSGI.D_jaspar_format.txt
MEME format	ZN648.H14RSNP.0.PSGI.D_meme_format.meme
Transfac format	ZN648.H14RSNP.0.PSGI.D_transfac_format.txt
Homer format	ZN648.H14RSNP.0.PSGI.D_homer_format_0.001.txt ZN648.H14RSNP.0.PSGI.D_homer_format_0.0005.txt ZN648.H14RSNP.0.PSGI.D_homer_format_0.0001.txt

PCM

	A	C	G	T
01	240.25	50.25	532.25	70.25
02	96.0	135.0	8.0	654.0
03	1.0	891.0	0.0	1.0
04	887.0	3.0	2.0	1.0
05	0.0	3.0	883.0	7.0
06	2.0	882.0	1.0	8.0
07	94.0	4.0	780.0	15.0
08	90.0	384.0	40.0	379.0
09	179.0	275.0	171.0	268.0
10	164.0	390.0	206.0	133.0
11	159.0	376.0	172.0	186.0
12	187.0	359.0	115.0	232.0
13	188.0	386.0	100.0	219.0
14	167.0	423.0	121.0	182.0
15	212.0	350.0	149.0	182.0
16	217.0	262.0	227.0	187.0
17	167.0	299.0	217.0	210.0
18	83.0	392.0	138.0	280.0
19	12.0	532.0	37.0	312.0
20	3.0	456.0	13.0	421.0
21	3.0	787.0	2.0	101.0
22	1.0	877.0	0.0	15.0
23	10.0	813.0	3.0	67.0
24	28.0	638.0	5.0	222.0
25	99.25	380.25	7.25	406.25
26	189.75	362.75	21.75	318.75

PFM

	A	C	G	T
01	0.269	0.056	0.596	0.079
02	0.108	0.151	0.009	0.732
03	0.001	0.998	0.0	0.001
04	0.993	0.003	0.002	0.001
05	0.0	0.003	0.989	0.008
06	0.002	0.988	0.001	0.009
07	0.105	0.004	0.873	0.017
08	0.101	0.43	0.045	0.424
09	0.2	0.308	0.191	0.3
10	0.184	0.437	0.231	0.149
11	0.178	0.421	0.193	0.208
12	0.209	0.402	0.129	0.26
13	0.211	0.432	0.112	0.245
14	0.187	0.474	0.135	0.204
15	0.237	0.392	0.167	0.204
16	0.243	0.293	0.254	0.209
17	0.187	0.335	0.243	0.235
18	0.093	0.439	0.155	0.314
19	0.013	0.596	0.041	0.349
20	0.003	0.511	0.015	0.471
21	0.003	0.881	0.002	0.113
22	0.001	0.982	0.0	0.017
23	0.011	0.91	0.003	0.075
24	0.031	0.714	0.006	0.249
25	0.111	0.426	0.008	0.455
26	0.212	0.406	0.024	0.357

PWM

	A	C	G	T
01	0.073	-1.466	0.864	-1.14
02	-0.834	-0.498	-3.144	1.07
03	-4.423	1.378	-4.886	-4.423
04	1.374	-3.869	-4.108	-4.423
05	-4.886	-3.869	1.369	-3.253
06	-4.108	1.368	-4.423	-3.144
07	-0.855	-3.676	1.246	-2.601
08	-0.897	0.539	-1.685	0.526
09	-0.219	0.207	-0.264	0.181
10	-0.306	0.555	-0.08	-0.513
11	-0.336	0.518	-0.259	-0.181
12	-0.176	0.472	-0.656	0.038
13	-0.17	0.544	-0.794	-0.019
14	-0.288	0.636	-0.606	-0.203
15	-0.051	0.447	-0.401	-0.203
16	-0.028	0.159	0.017	-0.176
17	-0.288	0.29	-0.028	-0.061
18	-0.977	0.56	-0.476	0.225
19	-2.799	0.864	-1.76	0.333
20	-3.869	0.71	-2.728	0.631
21	-3.869	1.255	-4.108	-0.784
22	-4.423	1.363	-4.886	-2.601
23	-2.956	1.287	-3.869	-1.186
24	-2.025	1.045	-3.514	-0.006
25	-0.801	0.529	-3.224	0.595
26	-0.161	0.483	-2.261	0.354

Standard thresholds

P-value	Threshold
0.001	-0.52104
0.0005	1.04376
0.0001	4.34006