ZN648.H14INVIVO.0.PSGI.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ZN648.H14INVIVO.0.PSGI.A
Gene (human)	ZNF648 (GeneCards)
Gene synonyms (human)
Gene (mouse)
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	A

Motif length	13
Consensus	nSbCTCCCCYhYY
GC content	70.62%
Information content (bits; total / per base)	13.006 / 1.0
Data sources	ChIP-Seq + HT-SELEX + Genomic HT-SELEX + SMiLe-Seq
Aligned words	500
Previous names

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	Centrality, median	Centrality, best
Overall	2 (2)	0.777	0.817	0.637	0.694	0.688	0.75	42.816	71.745

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
GFPIVT, 1 experiments	median	0.956	0.926	0.943	0.907	0.917	0.878
GFPIVT, 1 experiments	best	0.956	0.926	0.943	0.907	0.917	0.878

Genomic HT-SELEX benchmarking		Centrality	pseudo-auROC	auROC	auPR
overall, 2 experiments	median	143.425	0.7	0.758	0.635
overall, 2 experiments	best	313.77	0.771	0.832	0.682
Lysate, 1 experiments	median	81.092	0.693	0.7	0.596
Lysate, 1 experiments	best	119.62	0.706	0.713	0.611
GFPIVT, 1 experiments	median	292.796	0.744	0.818	0.667
GFPIVT, 1 experiments	best	313.77	0.771	0.832	0.682

SMiLE-Seq benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 2 experiments	median	0.895	0.856	0.811	0.784	0.712	0.706
Overall, 2 experiments	best	0.946	0.914	0.909	0.871	0.821	0.794

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	More than 3 adjacent zinc fingers {2.3.3} (TFClass)
TF subfamily	Unclassified {2.3.3.0} (TFClass)
TFClass ID	TFClass: 2.3.3.0.94
HGNC	HGNC:18190
MGI
EntrezGene (human)	GeneID:127665 (SSTAR profile)
EntrezGene (mouse)
UniProt ID (human)	ZN648_HUMAN
UniProt ID (mouse)
UniProt AC (human)	Q5T619 (TFClass)
UniProt AC (mouse)
GRECO-DB-TF	yes

ChIP-Seq	2 human, 0 mouse
HT-SELEX	1 overall: 0 Lysate, 0 IVT, 1 GFPIVT
Genomic HT-SELEX	2 overall: 1 Lysate, 0 IVT, 1 GFPIVT
SMiLE-Seq	2
PBM	0

PCM	ZN648.H14INVIVO.0.PSGI.A.pcm
PWM	ZN648.H14INVIVO.0.PSGI.A.pwm
PFM	ZN648.H14INVIVO.0.PSGI.A.pfm
Threshold to P-value map	ZN648.H14INVIVO.0.PSGI.A.thr
Motif in other formats
JASPAR format	ZN648.H14INVIVO.0.PSGI.A_jaspar_format.txt
MEME format	ZN648.H14INVIVO.0.PSGI.A_meme_format.meme
Transfac format	ZN648.H14INVIVO.0.PSGI.A_transfac_format.txt
Homer format	ZN648.H14INVIVO.0.PSGI.A_homer_format_0.001.txt ZN648.H14INVIVO.0.PSGI.A_homer_format_0.0005.txt ZN648.H14INVIVO.0.PSGI.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	151.0	110.0	167.0	72.0
02	74.0	76.0	314.0	36.0
03	32.0	113.0	259.0	96.0
04	3.0	486.0	5.0	6.0
05	4.0	1.0	22.0	473.0
06	1.0	430.0	2.0	67.0
07	1.0	491.0	0.0	8.0
08	4.0	466.0	2.0	28.0
09	2.0	465.0	2.0	31.0
10	13.0	245.0	6.0	236.0
11	66.0	179.0	22.0	233.0
12	53.0	353.0	29.0	65.0
13	52.0	308.0	37.0	103.0

PFM

	A	C	G	T
01	0.302	0.22	0.334	0.144
02	0.148	0.152	0.628	0.072
03	0.064	0.226	0.518	0.192
04	0.006	0.972	0.01	0.012
05	0.008	0.002	0.044	0.946
06	0.002	0.86	0.004	0.134
07	0.002	0.982	0.0	0.016
08	0.008	0.932	0.004	0.056
09	0.004	0.93	0.004	0.062
10	0.026	0.49	0.012	0.472
11	0.132	0.358	0.044	0.466
12	0.106	0.706	0.058	0.13
13	0.104	0.616	0.074	0.206

PWM

	A	C	G	T
01	0.187	-0.126	0.287	-0.543
02	-0.516	-0.49	0.914	-1.215
03	-1.328	-0.1	0.722	-0.26
04	-3.325	1.349	-2.961	-2.819
05	-3.126	-3.903	-1.681	1.322
06	-3.903	1.227	-3.573	-0.613
07	-3.903	1.359	-4.4	-2.584
08	-3.126	1.307	-3.573	-1.454
09	-3.573	1.305	-3.573	-1.358
10	-2.163	0.667	-2.819	0.63
11	-0.628	0.355	-1.681	0.617
12	-0.841	1.03	-1.421	-0.643
13	-0.86	0.894	-1.189	-0.191

Standard thresholds

P-value	Threshold
0.001	3.82096
0.0005	4.88691
0.0001	7.09381