MotifZN646.H14INVIVO.0.PSG.A
Gene (human)ZNF646
(GeneCards)
Gene synonyms (human)KIAA0296
Gene (mouse)Zfp646
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
A
Motif length21
ConsensusGTGTGTnTGTGTGTKKKKKGK
GC content47.58%
Information content (bits; total / per base)25.76 / 1.227
Data sourcesChIP-Seq + HT-SELEX + Genomic HT-SELEX
Aligned words262
Previous names

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best Centrality, median Centrality, best
Overall 2 (2) 0.882 0.914 0.774 0.806 0.832 0.874 55.762 110.886

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
overall, 4 experiments median 0.913 0.875 0.843 0.803 0.754 0.728
best 0.929 0.896 0.866 0.827 0.765 0.744
IVT, 1 experiments median 0.899 0.857 0.831 0.787 0.757 0.722
best 0.899 0.857 0.831 0.787 0.757 0.722
GFPIVT, 3 experiments median 0.926 0.893 0.855 0.819 0.751 0.733
best 0.929 0.896 0.866 0.827 0.765 0.744

Genomic HT-SELEX benchmarking Centrality pseudo-auROC auROC auPR
overall, 5 experiments median 60.481 0.913 0.889 0.734
best 309.469 0.976 0.917 0.778
IVT, 2 experiments median 73.149 0.86 0.832 0.641
best 115.62 0.938 0.868 0.673
GFPIVT, 3 experiments median 60.481 0.913 0.891 0.735
best 309.469 0.976 0.917 0.778
TF superclassZinc-coordinating DNA-binding domains {2} (TFClass)
TF classC2H2 zinc finger factors {2.3} (TFClass)
TF familyMultiple dispersed zinc fingers {2.3.4} (TFClass)
TF subfamilyUnclassified {2.3.4.0} (TFClass)
TFClass IDTFClass: 2.3.4.0.13
HGNCHGNC:29004
MGIMGI:3665412
EntrezGene (human)GeneID:9726
(SSTAR profile)
EntrezGene (mouse)GeneID:233905
(SSTAR profile)
UniProt ID (human)ZN646_HUMAN
UniProt ID (mouse)ZN646_MOUSE
UniProt AC (human)O15015
(TFClass)
UniProt AC (mouse)Q6NV66
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 2 human, 0 mouse
HT-SELEX 4 overall: 0 Lysate, 1 IVT, 3 GFPIVT
Genomic HT-SELEX 5 overall: 0 Lysate, 2 IVT, 3 GFPIVT
SMiLE-Seq 0
PBM 0
PCM
ACGT
011.01.0243.017.0
022.02.05.0253.0
033.01.0250.08.0
040.00.01.0261.0
0522.03.0223.014.0
063.017.017.0225.0
0753.063.091.055.0
081.013.026.0222.0
0910.07.0218.027.0
101.00.05.0256.0
119.014.0236.03.0
129.01.00.0252.0
1311.00.0250.01.0
1413.07.020.0222.0
156.016.0171.069.0
1615.00.0115.0132.0
173.06.078.0175.0
184.02.0164.092.0
192.04.078.0178.0
200.00.0158.0104.0
211.03.0109.0149.0
PFM
ACGT
010.0040.0040.9270.065
020.0080.0080.0190.966
030.0110.0040.9540.031
040.00.00.0040.996
050.0840.0110.8510.053
060.0110.0650.0650.859
070.2020.240.3470.21
080.0040.050.0990.847
090.0380.0270.8320.103
100.0040.00.0190.977
110.0340.0530.9010.011
120.0340.0040.00.962
130.0420.00.9540.004
140.050.0270.0760.847
150.0230.0610.6530.263
160.0570.00.4390.504
170.0110.0230.2980.668
180.0150.0080.6260.351
190.0080.0150.2980.679
200.00.00.6030.397
210.0040.0110.4160.569
PWM
ACGT
01-3.331-3.3311.296-1.291
02-2.982-2.982-2.3481.336
03-2.723-3.3311.324-1.963
04-3.872-3.872-3.3311.367
05-1.051-2.7231.21-1.469
06-2.723-1.291-1.2911.219
07-0.207-0.0380.323-0.171
08-3.331-1.536-0.8931.206
09-1.77-2.0761.188-0.857
10-3.331-3.872-2.3481.348
11-1.862-1.4691.267-2.723
12-1.862-3.331-3.8721.332
13-1.686-3.8721.324-3.331
14-1.536-2.076-1.141.206
15-2.203-1.3470.9470.051
16-1.406-3.8720.5540.69
17-2.723-2.2030.1710.97
18-2.518-2.9820.9050.334
19-2.982-2.5180.1710.986
20-3.872-3.8720.8680.455
21-3.331-2.7230.5010.81
Standard thresholds
P-value Threshold
0.001 -2.22504
0.0005 -0.64979
0.0001 2.70941