ZN646.H14INVITRO.0.PSG.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ZN646.H14INVITRO.0.PSG.A
Gene (human)	ZNF646 (GeneCards)
Gene synonyms (human)	KIAA0296
Gene (mouse)	Zfp646
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	A

Motif length	14
Consensus	dTTGTGTGTCCRhn
GC content	45.11%
Information content (bits; total / per base)	18.94 / 1.353
Data sources	ChIP-Seq + HT-SELEX + Genomic HT-SELEX
Aligned words	9445
Previous names

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	Centrality, median	Centrality, best
Overall	2 (2)	0.843	0.875	0.672	0.703	0.638	0.721	40.633	79.469

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
overall, 4 experiments	median	0.982	0.97	0.97	0.954	0.915	0.875
overall, 4 experiments	best	0.999	0.999	0.982	0.981	0.943	0.931
IVT, 1 experiments	median	0.972	0.952	0.957	0.933	0.937	0.907
IVT, 1 experiments	best	0.972	0.952	0.957	0.933	0.937	0.907
GFPIVT, 3 experiments	median	0.991	0.988	0.982	0.974	0.893	0.843
GFPIVT, 3 experiments	best	0.999	0.999	0.982	0.981	0.943	0.931

Genomic HT-SELEX benchmarking		Centrality	pseudo-auROC	auROC	auPR
overall, 5 experiments	median	64.444	0.711	0.887	0.71
overall, 5 experiments	best	225.854	0.863	0.929	0.902
IVT, 2 experiments	median	73.919	0.669	0.823	0.666
IVT, 2 experiments	best	87.268	0.71	0.873	0.687
GFPIVT, 3 experiments	median	64.444	0.765	0.894	0.763
GFPIVT, 3 experiments	best	225.854	0.863	0.929	0.902

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	Multiple dispersed zinc fingers {2.3.4} (TFClass)
TF subfamily	Unclassified {2.3.4.0} (TFClass)
TFClass ID	TFClass: 2.3.4.0.13
HGNC	HGNC:29004
MGI	MGI:3665412
EntrezGene (human)	GeneID:9726 (SSTAR profile)
EntrezGene (mouse)	GeneID:233905 (SSTAR profile)
UniProt ID (human)	ZN646_HUMAN
UniProt ID (mouse)	ZN646_MOUSE
UniProt AC (human)	O15015 (TFClass)
UniProt AC (mouse)	Q6NV66 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	2 human, 0 mouse
HT-SELEX	4 overall: 0 Lysate, 1 IVT, 3 GFPIVT
Genomic HT-SELEX	5 overall: 0 Lysate, 2 IVT, 3 GFPIVT
SMiLE-Seq	0
PBM	0

PCM	ZN646.H14INVITRO.0.PSG.A.pcm
PWM	ZN646.H14INVITRO.0.PSG.A.pwm
PFM	ZN646.H14INVITRO.0.PSG.A.pfm
Threshold to P-value map	ZN646.H14INVITRO.0.PSG.A.thr
Motif in other formats
JASPAR format	ZN646.H14INVITRO.0.PSG.A_jaspar_format.txt
MEME format	ZN646.H14INVITRO.0.PSG.A_meme_format.meme
Transfac format	ZN646.H14INVITRO.0.PSG.A_transfac_format.txt
Homer format	ZN646.H14INVITRO.0.PSG.A_homer_format_0.001.txt ZN646.H14INVITRO.0.PSG.A_homer_format_0.0005.txt ZN646.H14INVITRO.0.PSG.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	3438.0	245.0	2661.0	3101.0
02	10.0	1.0	51.0	9383.0
03	2.0	2.0	1.0	9440.0
04	0.0	0.0	9445.0	0.0
05	0.0	21.0	0.0	9424.0
06	0.0	0.0	9445.0	0.0
07	5.0	49.0	63.0	9328.0
08	276.0	304.0	8789.0	76.0
09	113.0	14.0	96.0	9222.0
10	796.0	8050.0	204.0	395.0
11	65.0	8512.0	177.0	691.0
12	5757.0	460.0	2056.0	1172.0
13	1227.5	2978.5	669.5	4569.5
14	1991.75	1718.75	3635.75	2098.75

PFM

	A	C	G	T
01	0.364	0.026	0.282	0.328
02	0.001	0.0	0.005	0.993
03	0.0	0.0	0.0	0.999
04	0.0	0.0	1.0	0.0
05	0.0	0.002	0.0	0.998
06	0.0	0.0	1.0	0.0
07	0.001	0.005	0.007	0.988
08	0.029	0.032	0.931	0.008
09	0.012	0.001	0.01	0.976
10	0.084	0.852	0.022	0.042
11	0.007	0.901	0.019	0.073
12	0.61	0.049	0.218	0.124
13	0.13	0.315	0.071	0.484
14	0.211	0.182	0.385	0.222

PWM

	A	C	G	T
01	0.375	-2.257	0.119	0.272
02	-5.259	-6.578	-3.792	1.379
03	-6.312	-6.312	-6.578	1.385
04	-6.94	-6.94	1.386	-6.94
05	-6.94	-4.62	-6.94	1.383
06	-6.94	-6.94	1.386	-6.94
07	-5.782	-3.83	-3.589	1.373
08	-2.139	-2.043	1.314	-3.408
09	-3.02	-4.977	-3.18	1.362
10	-1.085	1.226	-2.439	-1.783
11	-3.559	1.282	-2.579	-1.226
12	0.891	-1.632	-0.138	-0.699
13	-0.653	0.232	-1.258	0.66
14	-0.17	-0.317	0.431	-0.118

Standard thresholds

P-value	Threshold
0.001	-2.23619
0.0005	-0.32324
0.0001	3.662575