MotifZN646.H14CORE.0.PSG.A
Gene (human)ZNF646
(GeneCards)
Gene synonyms (human)KIAA0296
Gene (mouse)Zfp646
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
A
Motif length25
ConsensusTGTGTGTGYdTGTGTGTGTGTGTGK
GC content49.94%
Information content (bits; total / per base)31.021 / 1.241
Data sourcesChIP-Seq + HT-SELEX + Genomic HT-SELEX
Aligned words446
Previous names

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best Centrality, median Centrality, best
Overall 2 (2) 0.865 0.912 0.766 0.835 0.807 0.843 56.337 112.602

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
overall, 4 experiments median 0.921 0.886 0.846 0.808 0.764 0.734
best 0.939 0.922 0.87 0.831 0.785 0.752
IVT, 1 experiments median 0.914 0.877 0.856 0.813 0.785 0.748
best 0.914 0.877 0.856 0.813 0.785 0.748
GFPIVT, 3 experiments median 0.928 0.894 0.836 0.803 0.749 0.72
best 0.939 0.922 0.87 0.831 0.778 0.752

Genomic HT-SELEX benchmarking Centrality pseudo-auROC auROC auPR
overall, 5 experiments median 45.222 0.965 0.896 0.763
best 314.26 0.979 0.931 0.819
IVT, 2 experiments median 80.362 0.889 0.852 0.702
best 128.086 0.965 0.896 0.748
GFPIVT, 3 experiments median 45.222 0.965 0.906 0.78
best 314.26 0.979 0.931 0.819
TF superclassZinc-coordinating DNA-binding domains {2} (TFClass)
TF classC2H2 zinc finger factors {2.3} (TFClass)
TF familyMultiple dispersed zinc fingers {2.3.4} (TFClass)
TF subfamilyUnclassified {2.3.4.0} (TFClass)
TFClass IDTFClass: 2.3.4.0.13
HGNCHGNC:29004
MGIMGI:3665412
EntrezGene (human)GeneID:9726
(SSTAR profile)
EntrezGene (mouse)GeneID:233905
(SSTAR profile)
UniProt ID (human)ZN646_HUMAN
UniProt ID (mouse)ZN646_MOUSE
UniProt AC (human)O15015
(TFClass)
UniProt AC (mouse)Q6NV66
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 2 human, 0 mouse
HT-SELEX 4 overall: 0 Lysate, 1 IVT, 3 GFPIVT
Genomic HT-SELEX 5 overall: 0 Lysate, 2 IVT, 3 GFPIVT
SMiLE-Seq 0
PBM 0
PCM
ACGT
016.010.022.0408.0
025.06.0433.02.0
033.04.04.0435.0
047.03.0433.03.0
051.09.03.0433.0
065.06.0430.05.0
073.05.010.0428.0
085.051.0380.010.0
0915.0251.049.0131.0
10213.038.0118.077.0
118.024.051.0363.0
1213.010.0371.052.0
1311.019.041.0375.0
1417.025.0372.032.0
1517.026.025.0378.0
1618.016.0382.030.0
1713.030.023.0380.0
1837.030.0370.09.0
197.051.019.0369.0
2034.034.0366.012.0
214.062.018.0362.0
2237.014.0385.010.0
235.026.023.0392.0
2429.013.0380.024.0
254.041.056.0345.0
PFM
ACGT
010.0130.0220.0490.915
020.0110.0130.9710.004
030.0070.0090.0090.975
040.0160.0070.9710.007
050.0020.020.0070.971
060.0110.0130.9640.011
070.0070.0110.0220.96
080.0110.1140.8520.022
090.0340.5630.110.294
100.4780.0850.2650.173
110.0180.0540.1140.814
120.0290.0220.8320.117
130.0250.0430.0920.841
140.0380.0560.8340.072
150.0380.0580.0560.848
160.040.0360.8570.067
170.0290.0670.0520.852
180.0830.0670.830.02
190.0160.1140.0430.827
200.0760.0760.8210.027
210.0090.1390.040.812
220.0830.0310.8630.022
230.0110.0580.0520.879
240.0650.0290.8520.054
250.0090.0920.1260.774
PWM
ACGT
01-2.709-2.283-1.571.287
02-2.852-2.7091.347-3.468
03-3.218-3.018-3.0181.351
04-2.585-3.2181.347-3.218
05-3.801-2.374-3.2181.347
06-2.852-2.7091.34-2.852
07-3.218-2.852-2.2831.335
08-2.852-0.7661.217-2.283
09-1.9230.804-0.8050.159
100.641-1.0510.056-0.364
11-2.474-1.488-0.7661.171
12-2.052-2.2831.193-0.747
13-2.2-1.706-0.9781.203
14-1.808-1.451.195-1.215
15-1.808-1.413-1.451.211
16-1.756-1.8641.222-1.277
17-2.052-1.277-1.5281.217
18-1.076-1.2771.19-2.374
19-2.585-0.766-1.7061.187
20-1.157-1.1571.179-2.123
21-3.018-0.576-1.7561.168
22-1.076-1.9851.23-2.283
23-2.852-1.413-1.5281.248
24-1.309-2.0521.217-1.488
25-3.018-0.978-0.6751.12
Standard thresholds
P-value Threshold
0.001 -4.23039
0.0005 -2.63014
0.0001 0.81576