ZN536.H14INVIVO.0.SGI.D motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ZN536.H14INVIVO.0.SGI.D
Gene (human)	ZNF536 (GeneCards)
Gene synonyms (human)	KIAA0390
Gene (mouse)	Znf536
Gene synonyms (mouse)	Kiaa0390, Zfp536
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	D

Motif length	8
Consensus	nWTAAGdn
GC content	28.7%
Information content (bits; total / per base)	8.119 / 1.015
Data sources	HT-SELEX + Genomic HT-SELEX + SMiLe-Seq
Aligned words	6492
Previous names

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
overall, 3 experiments	median	0.722	0.714	0.601	0.614	0.546	0.563
overall, 3 experiments	best	0.932	0.902	0.871	0.834	0.755	0.744
IVT, 2 experiments	median	0.645	0.623	0.585	0.575	0.543	0.546
IVT, 2 experiments	best	0.722	0.714	0.601	0.614	0.546	0.563
GFPIVT, 1 experiments	median	0.932	0.902	0.871	0.834	0.755	0.744
GFPIVT, 1 experiments	best	0.932	0.902	0.871	0.834	0.755	0.744

Genomic HT-SELEX benchmarking		Centrality	pseudo-auROC	auROC	auPR
overall, 2 experiments	median	70.273	0.657	0.773	0.786
overall, 2 experiments	best	93.244	0.787	0.955	0.946
IVT, 1 experiments	median	93.244	0.527	0.59	0.625
IVT, 1 experiments	best	93.244	0.527	0.59	0.625
GFPIVT, 1 experiments	median	47.301	0.787	0.955	0.946
GFPIVT, 1 experiments	best	47.301	0.787	0.955	0.946

SMiLE-Seq benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 4 experiments	median	0.634	0.595	0.581	0.563	0.55	0.542
Overall, 4 experiments	best	0.731	0.675	0.654	0.621	0.592	0.581

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	Multiple dispersed zinc fingers {2.3.4} (TFClass)
TF subfamily	ZNF219-like {2.3.4.2} (TFClass)
TFClass ID	TFClass: 2.3.4.2.2
HGNC	HGNC:29025
MGI	MGI:1926102
EntrezGene (human)	GeneID:9745 (SSTAR profile)
EntrezGene (mouse)	GeneID:243937 (SSTAR profile)
UniProt ID (human)	ZN536_HUMAN
UniProt ID (mouse)	ZN536_MOUSE
UniProt AC (human)	O15090 (TFClass)
UniProt AC (mouse)	Q8K083 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 0 mouse
HT-SELEX	3 overall: 0 Lysate, 2 IVT, 1 GFPIVT
Genomic HT-SELEX	2 overall: 0 Lysate, 1 IVT, 1 GFPIVT
SMiLE-Seq	4
PBM	0

PCM	ZN536.H14INVIVO.0.SGI.D.pcm
PWM	ZN536.H14INVIVO.0.SGI.D.pwm
PFM	ZN536.H14INVIVO.0.SGI.D.pfm
Threshold to P-value map	ZN536.H14INVIVO.0.SGI.D.thr
Motif in other formats
JASPAR format	ZN536.H14INVIVO.0.SGI.D_jaspar_format.txt
MEME format	ZN536.H14INVIVO.0.SGI.D_meme_format.meme
Transfac format	ZN536.H14INVIVO.0.SGI.D_transfac_format.txt
Homer format	ZN536.H14INVIVO.0.SGI.D_homer_format_0.001.txt ZN536.H14INVIVO.0.SGI.D_homer_format_0.0005.txt ZN536.H14INVIVO.0.SGI.D_homer_format_0.0001.txt

PCM

	A	C	G	T
01	1931.0	1060.0	1694.0	1807.0
02	818.0	508.0	127.0	5039.0
03	0.0	0.0	0.0	6492.0
04	6492.0	0.0	0.0	0.0
05	6492.0	0.0	0.0	0.0
06	1474.0	0.0	4759.0	259.0
07	1588.25	651.25	2599.25	1653.25
08	1431.25	1760.25	1749.25	1551.25

PFM

	A	C	G	T
01	0.297	0.163	0.261	0.278
02	0.126	0.078	0.02	0.776
03	0.0	0.0	0.0	1.0
04	1.0	0.0	0.0	0.0
05	1.0	0.0	0.0	0.0
06	0.227	0.0	0.733	0.04
07	0.245	0.1	0.4	0.255
08	0.22	0.271	0.269	0.239

PWM

	A	C	G	T
01	0.174	-0.425	0.043	0.107
02	-0.684	-1.159	-2.532	1.132
03	-6.607	-6.607	-6.607	1.385
04	1.385	-6.607	-6.607	-6.607
05	1.385	-6.607	-6.607	-6.607
06	-0.096	-6.607	1.075	-1.828
07	-0.022	-0.911	0.47	0.018
08	-0.126	0.081	0.075	-0.045

Standard thresholds

P-value	Threshold
0.001	5.57311
0.0005	6.37246
0.0001	6.926435