ZN500.H14INVIVO.0.PSGI.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ZN500.H14INVIVO.0.PSGI.A
Gene (human)	ZNF500 (GeneCards)
Gene synonyms (human)	KIAA0557, ZKSCAN18
Gene (mouse)
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	A

Motif length	15
Consensus	bbGTCYMCAChnbhb
GC content	62.92%
Information content (bits; total / per base)	10.993 / 0.733
Data sources	ChIP-Seq + HT-SELEX + Genomic HT-SELEX + SMiLe-Seq
Aligned words	500
Previous names

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	Centrality, median	Centrality, best
Overall	2 (2)	0.728	0.74	0.584	0.595	0.685	0.714	23.228	26.0

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
GFPIVT, 1 experiments	median	0.999	0.998	0.973	0.971	0.797	0.823
GFPIVT, 1 experiments	best	0.999	0.998	0.973	0.971	0.797	0.823

Genomic HT-SELEX benchmarking		Centrality	pseudo-auROC	auROC	auPR
overall, 2 experiments	median	14.953	0.7	0.728	0.608
overall, 2 experiments	best	118.824	0.884	0.84	0.741
Lysate, 1 experiments	median	6.071	0.565	0.637	0.517
Lysate, 1 experiments	best	6.071	0.565	0.637	0.517
GFPIVT, 1 experiments	median	21.208	0.835	0.819	0.699
GFPIVT, 1 experiments	best	118.824	0.884	0.84	0.741

SMiLE-Seq benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 1 experiments	median	0.989	0.981	0.952	0.94	0.814	0.821
Overall, 1 experiments	best	0.989	0.981	0.952	0.94	0.814	0.821

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	More than 3 adjacent zinc fingers {2.3.3} (TFClass)
TF subfamily	ZNF500-like {2.3.3.19} (TFClass)
TFClass ID	TFClass: 2.3.3.19.1
HGNC	HGNC:23716
MGI
EntrezGene (human)	GeneID:26048 (SSTAR profile)
EntrezGene (mouse)
UniProt ID (human)	ZN500_HUMAN
UniProt ID (mouse)
UniProt AC (human)	O60304 (TFClass)
UniProt AC (mouse)
GRECO-DB-TF	yes

ChIP-Seq	2 human, 0 mouse
HT-SELEX	1 overall: 0 Lysate, 0 IVT, 1 GFPIVT
Genomic HT-SELEX	2 overall: 1 Lysate, 0 IVT, 1 GFPIVT
SMiLE-Seq	1
PBM	0

PCM	ZN500.H14INVIVO.0.PSGI.A.pcm
PWM	ZN500.H14INVIVO.0.PSGI.A.pwm
PFM	ZN500.H14INVIVO.0.PSGI.A.pfm
Threshold to P-value map	ZN500.H14INVIVO.0.PSGI.A.thr
Motif in other formats
JASPAR format	ZN500.H14INVIVO.0.PSGI.A_jaspar_format.txt
MEME format	ZN500.H14INVIVO.0.PSGI.A_meme_format.meme
Transfac format	ZN500.H14INVIVO.0.PSGI.A_transfac_format.txt
Homer format	ZN500.H14INVIVO.0.PSGI.A_homer_format_0.001.txt ZN500.H14INVIVO.0.PSGI.A_homer_format_0.0005.txt ZN500.H14INVIVO.0.PSGI.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	38.0	161.0	225.0	76.0
02	42.0	283.0	64.0	111.0
03	32.0	36.0	415.0	17.0
04	17.0	38.0	42.0	403.0
05	2.0	449.0	10.0	39.0
06	8.0	236.0	1.0	255.0
07	312.0	111.0	17.0	60.0
08	18.0	408.0	51.0	23.0
09	436.0	3.0	39.0	22.0
10	11.0	461.0	21.0	7.0
11	41.0	245.0	34.0	180.0
12	90.0	128.0	140.0	142.0
13	65.0	239.0	115.0	81.0
14	57.0	338.0	48.0	57.0
15	47.0	288.0	73.0	92.0

PFM

	A	C	G	T
01	0.076	0.322	0.45	0.152
02	0.084	0.566	0.128	0.222
03	0.064	0.072	0.83	0.034
04	0.034	0.076	0.084	0.806
05	0.004	0.898	0.02	0.078
06	0.016	0.472	0.002	0.51
07	0.624	0.222	0.034	0.12
08	0.036	0.816	0.102	0.046
09	0.872	0.006	0.078	0.044
10	0.022	0.922	0.042	0.014
11	0.082	0.49	0.068	0.36
12	0.18	0.256	0.28	0.284
13	0.13	0.478	0.23	0.162
14	0.114	0.676	0.096	0.114
15	0.094	0.576	0.146	0.184

PWM

	A	C	G	T
01	-1.163	0.25	0.582	-0.49
02	-1.067	0.81	-0.658	-0.117
03	-1.328	-1.215	1.191	-1.92
04	-1.92	-1.163	-1.067	1.162
05	-3.573	1.27	-2.394	-1.138
06	-2.584	0.63	-3.903	0.707
07	0.907	-0.117	-1.92	-0.721
08	-1.868	1.174	-0.879	-1.64
09	1.241	-3.325	-1.138	-1.681
10	-2.311	1.296	-1.725	-2.694
11	-1.09	0.667	-1.27	0.361
12	-0.324	0.023	0.112	0.126
13	-0.643	0.642	-0.082	-0.427
14	-0.771	0.987	-0.938	-0.771
15	-0.958	0.828	-0.529	-0.302

Standard thresholds

P-value	Threshold
0.001	4.52241
0.0005	5.37291
0.0001	7.14591