ZN493.H14RSNP.0.PSGI.D motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ZN493.H14RSNP.0.PSGI.D
Gene (human)	ZNF493 (GeneCards)
Gene synonyms (human)
Gene (mouse)
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	D

Motif length	26
Consensus	nhhnddnYWhCCRKRMCAGTGCCChh
GC content	57.64%
Information content (bits; total / per base)	21.855 / 0.841
Data sources	ChIP-Seq + HT-SELEX + Genomic HT-SELEX + SMiLe-Seq
Aligned words	1339
Previous names

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	Centrality, median	Centrality, best
Overall	3 (4)	0.96	0.986	0.957	0.984	0.956	0.995	51.553	129.699

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
GFPIVT, 2 experiments	median	0.878	0.887	0.807	0.82	0.778	0.789
GFPIVT, 2 experiments	best	1.0	1.0	1.0	1.0	0.998	0.998

Genomic HT-SELEX benchmarking		Centrality	pseudo-auROC	auROC	auPR
GFPIVT, 2 experiments	median	542.738	0.934	0.946	0.94
GFPIVT, 2 experiments	best	974.721	0.97	0.985	0.975

SMiLE-Seq benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 2 experiments	median	0.898	0.889	0.822	0.817	0.716	0.724
Overall, 2 experiments	best	0.997	0.997	0.968	0.964	0.825	0.839

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	More than 3 adjacent zinc fingers {2.3.3} (TFClass)
TF subfamily	Unclassified {2.3.3.0} (TFClass)
TFClass ID	TFClass: 2.3.3.0.229
HGNC	HGNC:23708
MGI
EntrezGene (human)	GeneID:284443 (SSTAR profile)
EntrezGene (mouse)
UniProt ID (human)	ZN493_HUMAN
UniProt ID (mouse)
UniProt AC (human)	Q6ZR52 (TFClass)
UniProt AC (mouse)
GRECO-DB-TF	yes

ChIP-Seq	3 human, 0 mouse
HT-SELEX	2 overall: 0 Lysate, 0 IVT, 2 GFPIVT
Genomic HT-SELEX	2 overall: 0 Lysate, 0 IVT, 2 GFPIVT
SMiLE-Seq	2
PBM	0

PCM	ZN493.H14RSNP.0.PSGI.D.pcm
PWM	ZN493.H14RSNP.0.PSGI.D.pwm
PFM	ZN493.H14RSNP.0.PSGI.D.pfm
Threshold to P-value map	ZN493.H14RSNP.0.PSGI.D.thr
Motif in other formats
JASPAR format	ZN493.H14RSNP.0.PSGI.D_jaspar_format.txt
MEME format	ZN493.H14RSNP.0.PSGI.D_meme_format.meme
Transfac format	ZN493.H14RSNP.0.PSGI.D_transfac_format.txt
Homer format	ZN493.H14RSNP.0.PSGI.D_homer_format_0.001.txt ZN493.H14RSNP.0.PSGI.D_homer_format_0.0005.txt ZN493.H14RSNP.0.PSGI.D_homer_format_0.0001.txt

PCM

	A	C	G	T
01	307.75	230.75	524.75	275.75
02	250.5	635.5	216.5	236.5
03	197.0	789.0	131.0	222.0
04	251.0	233.0	522.0	333.0
05	565.0	122.0	442.0	210.0
06	340.0	122.0	630.0	247.0
07	238.0	236.0	496.0	369.0
08	168.0	901.0	73.0	197.0
09	837.0	162.0	74.0	266.0
10	184.0	326.0	143.0	686.0
11	53.0	1224.0	22.0	40.0
12	31.0	1214.0	31.0	63.0
13	629.0	31.0	541.0	138.0
14	187.0	26.0	870.0	256.0
15	893.0	142.0	233.0	71.0
16	772.0	357.0	14.0	196.0
17	6.0	1235.0	5.0	93.0
18	1293.0	8.0	28.0	10.0
19	3.0	1.0	1330.0	5.0
20	1.0	0.0	1.0	1337.0
21	40.0	2.0	1111.0	186.0
22	3.0	1333.0	2.0	1.0
23	10.0	1306.0	8.0	15.0
24	15.0	1209.0	15.0	100.0
25	722.25	148.25	118.25	350.25
26	310.75	338.75	151.75	537.75

PFM

	A	C	G	T
01	0.23	0.172	0.392	0.206
02	0.187	0.475	0.162	0.177
03	0.147	0.589	0.098	0.166
04	0.187	0.174	0.39	0.249
05	0.422	0.091	0.33	0.157
06	0.254	0.091	0.471	0.184
07	0.178	0.176	0.37	0.276
08	0.125	0.673	0.055	0.147
09	0.625	0.121	0.055	0.199
10	0.137	0.243	0.107	0.512
11	0.04	0.914	0.016	0.03
12	0.023	0.907	0.023	0.047
13	0.47	0.023	0.404	0.103
14	0.14	0.019	0.65	0.191
15	0.667	0.106	0.174	0.053
16	0.577	0.267	0.01	0.146
17	0.004	0.922	0.004	0.069
18	0.966	0.006	0.021	0.007
19	0.002	0.001	0.993	0.004
20	0.001	0.0	0.001	0.999
21	0.03	0.001	0.83	0.139
22	0.002	0.996	0.001	0.001
23	0.007	0.975	0.006	0.011
24	0.011	0.903	0.011	0.075
25	0.539	0.111	0.088	0.262
26	0.232	0.253	0.113	0.402

PWM

	A	C	G	T
01	-0.084	-0.37	0.448	-0.193
02	-0.288	0.638	-0.433	-0.345
03	-0.526	0.854	-0.93	-0.408
04	-0.286	-0.36	0.442	-0.005
05	0.521	-1.0	0.277	-0.463
06	0.015	-1.0	0.63	-0.302
07	-0.339	-0.347	0.391	0.097
08	-0.684	0.987	-1.504	-0.526
09	0.913	-0.72	-1.491	-0.229
10	-0.594	-0.026	-0.843	0.715
11	-1.815	1.293	-2.649	-2.086
12	-2.328	1.284	-2.328	-1.647
13	0.628	-2.328	0.478	-0.879
14	-0.578	-2.494	0.952	-0.267
15	0.978	-0.85	-0.36	-1.531
16	0.833	0.064	-3.059	-0.531
17	-3.765	1.302	-3.902	-1.267
18	1.347	-3.536	-2.424	-3.351
19	-4.25	-4.789	1.376	-3.902
20	-4.789	-5.231	-4.789	1.381
21	-2.086	-4.484	1.196	-0.583
22	-4.25	1.378	-4.484	-4.789
23	-3.351	1.357	-3.536	-2.997
24	-2.997	1.28	-2.997	-1.196
25	0.766	-0.808	-1.031	0.045
26	-0.074	0.012	-0.785	0.472

Standard thresholds

P-value	Threshold
0.001	-0.97234
0.0005	0.57761
0.0001	3.85601