ZN470.H14INVIVO.0.PSG.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ZN470.H14INVIVO.0.PSG.A
Gene (human)	ZNF470 (GeneCards)
Gene synonyms (human)	CZF1
Gene (mouse)
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	A

Motif length	16
Consensus	TCKTCTTCTGKTWvCT
GC content	39.24%
Information content (bits; total / per base)	21.35 / 1.334
Data sources	ChIP-Seq + HT-SELEX + Genomic HT-SELEX
Aligned words	9505
Previous names

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	Centrality, median	Centrality, best
Overall	2 (4)	0.872	0.939	0.843	0.915	0.882	0.949	87.984	208.886

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
GFPIVT, 2 experiments	median	0.874	0.881	0.801	0.815	0.723	0.745
GFPIVT, 2 experiments	best	1.0	0.999	0.998	0.997	0.905	0.918

Genomic HT-SELEX benchmarking		Centrality	pseudo-auROC	auROC	auPR
GFPIVT, 2 experiments	median	72.424	0.676	0.604	0.593
GFPIVT, 2 experiments	best	538.041	0.875	0.865	0.83

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	More than 3 adjacent zinc fingers {2.3.3} (TFClass)
TF subfamily	Unclassified {2.3.3.0} (TFClass)
TFClass ID	TFClass: 2.3.3.0.208
HGNC	HGNC:22220
MGI
EntrezGene (human)	GeneID:388566 (SSTAR profile)
EntrezGene (mouse)
UniProt ID (human)	ZN470_HUMAN
UniProt ID (mouse)
UniProt AC (human)	Q6ECI4 (TFClass)
UniProt AC (mouse)
GRECO-DB-TF	yes

ChIP-Seq	2 human, 0 mouse
HT-SELEX	2 overall: 0 Lysate, 0 IVT, 2 GFPIVT
Genomic HT-SELEX	2 overall: 0 Lysate, 0 IVT, 2 GFPIVT
SMiLE-Seq	0
PBM	0

PCM	ZN470.H14INVIVO.0.PSG.A.pcm
PWM	ZN470.H14INVIVO.0.PSG.A.pwm
PFM	ZN470.H14INVIVO.0.PSG.A.pfm
Threshold to P-value map	ZN470.H14INVIVO.0.PSG.A.thr
Motif in other formats
JASPAR format	ZN470.H14INVIVO.0.PSG.A_jaspar_format.txt
MEME format	ZN470.H14INVIVO.0.PSG.A_meme_format.meme
Transfac format	ZN470.H14INVIVO.0.PSG.A_transfac_format.txt
Homer format	ZN470.H14INVIVO.0.PSG.A_homer_format_0.001.txt ZN470.H14INVIVO.0.PSG.A_homer_format_0.0005.txt ZN470.H14INVIVO.0.PSG.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	173.0	99.0	94.0	9139.0
02	37.0	8430.0	35.0	1003.0
03	965.0	506.0	1087.0	6947.0
04	14.0	3.0	6.0	9482.0
05	0.0	9387.0	0.0	118.0
06	205.0	42.0	539.0	8719.0
07	12.0	3.0	2.0	9488.0
08	1.0	9207.0	1.0	296.0
09	303.0	38.0	443.0	8721.0
10	31.0	10.0	9429.0	35.0
11	633.0	55.0	3896.0	4921.0
12	86.0	722.0	272.0	8425.0
13	2387.0	1651.0	323.0	5144.0
14	4190.0	1951.0	2345.0	1019.0
15	233.25	7909.25	265.25	1097.25
16	557.75	448.75	473.75	8024.75

PFM

	A	C	G	T
01	0.018	0.01	0.01	0.961
02	0.004	0.887	0.004	0.106
03	0.102	0.053	0.114	0.731
04	0.001	0.0	0.001	0.998
05	0.0	0.988	0.0	0.012
06	0.022	0.004	0.057	0.917
07	0.001	0.0	0.0	0.998
08	0.0	0.969	0.0	0.031
09	0.032	0.004	0.047	0.918
10	0.003	0.001	0.992	0.004
11	0.067	0.006	0.41	0.518
12	0.009	0.076	0.029	0.886
13	0.251	0.174	0.034	0.541
14	0.441	0.205	0.247	0.107
15	0.025	0.832	0.028	0.115
16	0.059	0.047	0.05	0.844

PWM

	A	C	G	T
01	-2.608	-3.156	-3.207	1.346
02	-4.103	1.266	-4.156	-0.861
03	-0.9	-1.543	-0.781	1.072
04	-4.984	-6.108	-5.659	1.383
05	-6.946	1.373	-6.946	-2.984
06	-2.44	-3.983	-1.48	1.299
07	-5.115	-6.108	-6.318	1.384
08	-6.583	1.354	-6.583	-2.076
09	-2.053	-4.078	-1.676	1.3
10	-4.269	-5.265	1.378	-4.156
11	-1.32	-3.726	0.494	0.727
12	-3.294	-1.189	-2.16	1.265
13	0.005	-0.364	-1.99	0.772
14	0.567	-0.197	-0.013	-0.845
15	-2.312	1.202	-2.185	-0.772
16	-1.446	-1.663	-1.609	1.216

Standard thresholds

P-value	Threshold
0.001	-2.26004
0.0005	-0.49529
0.0001	3.20376