ZN454.H14INVIVO.0.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ZN454.H14INVIVO.0.P.B
Gene (human)	ZNF454 (GeneCards)
Gene synonyms (human)
Gene (mouse)
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	31
Consensus	RRRAYTCACCWGTRAAvCCATCWGGKCCWRG
GC content	50.9%
Information content (bits; total / per base)	35.276 / 1.138
Data sources	ChIP-Seq
Aligned words	167
Previous names	ZN454.H12INVIVO.0.P.B

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	2 (7)	0.626	0.893	0.593	0.892	0.507	0.903	5.258	13.411	52.292	106.77

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 2 experiments	median	0.434	0.463	0.449	0.471	0.463	0.477
Overall, 2 experiments	best	0.437	0.466	0.451	0.472	0.463	0.478
Methyl HT-SELEX, 1 experiments	median	0.437	0.466	0.451	0.472	0.463	0.478
Methyl HT-SELEX, 1 experiments	best	0.437	0.466	0.451	0.472	0.463	0.478
Non-Methyl HT-SELEX, 1 experiments	median	0.431	0.461	0.448	0.469	0.463	0.476
Non-Methyl HT-SELEX, 1 experiments	best	0.431	0.461	0.448	0.469	0.463	0.476

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	More than 3 adjacent zinc fingers {2.3.3} (TFClass)
TF subfamily	Unclassified {2.3.3.0} (TFClass)
TFClass ID	TFClass: 2.3.3.0.125
HGNC	HGNC:21200
MGI
EntrezGene (human)	GeneID:285676 (SSTAR profile)
EntrezGene (mouse)
UniProt ID (human)	ZN454_HUMAN
UniProt ID (mouse)
UniProt AC (human)	Q8N9F8 (TFClass)
UniProt AC (mouse)
GRECO-DB-TF	yes

ChIP-Seq	2 human, 0 mouse
HT-SELEX	1
Methyl-HT-SELEX	1
Genomic HT-SELEX	0 overall: 0 Lysate, 0 IVT, 0 GFPIVT
SMiLE-Seq	0
PBM	0

PCM	ZN454.H14INVIVO.0.P.B.pcm
PWM	ZN454.H14INVIVO.0.P.B.pwm
PFM	ZN454.H14INVIVO.0.P.B.pfm
Threshold to P-value map	ZN454.H14INVIVO.0.P.B.thr
Motif in other formats
JASPAR format	ZN454.H14INVIVO.0.P.B_jaspar_format.txt
MEME format	ZN454.H14INVIVO.0.P.B_meme_format.meme
Transfac format	ZN454.H14INVIVO.0.P.B_transfac_format.txt
Homer format	ZN454.H14INVIVO.0.P.B_homer_format_0.001.txt ZN454.H14INVIVO.0.P.B_homer_format_0.0005.txt ZN454.H14INVIVO.0.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	120.0	10.0	20.0	17.0
02	36.0	7.0	111.0	13.0
03	122.0	10.0	30.0	5.0
04	135.0	9.0	10.0	13.0
05	15.0	19.0	9.0	124.0
06	3.0	12.0	4.0	148.0
07	9.0	144.0	1.0	13.0
08	133.0	5.0	13.0	16.0
09	2.0	149.0	9.0	7.0
10	2.0	147.0	3.0	15.0
11	91.0	28.0	3.0	45.0
12	33.0	0.0	134.0	0.0
13	4.0	3.0	5.0	155.0
14	95.0	5.0	67.0	0.0
15	151.0	10.0	2.0	4.0
16	157.0	0.0	9.0	1.0
17	71.0	32.0	49.0	15.0
18	1.0	164.0	2.0	0.0
19	5.0	141.0	0.0	21.0
20	137.0	13.0	12.0	5.0
21	1.0	20.0	6.0	140.0
22	10.0	139.0	1.0	17.0
23	58.0	1.0	23.0	85.0
24	6.0	0.0	160.0	1.0
25	7.0	1.0	153.0	6.0
26	10.0	4.0	108.0	45.0
27	1.0	165.0	0.0	1.0
28	1.0	158.0	1.0	7.0
29	19.0	18.0	4.0	126.0
30	26.0	2.0	127.0	12.0
31	21.0	0.0	143.0	3.0

PFM

	A	C	G	T
01	0.719	0.06	0.12	0.102
02	0.216	0.042	0.665	0.078
03	0.731	0.06	0.18	0.03
04	0.808	0.054	0.06	0.078
05	0.09	0.114	0.054	0.743
06	0.018	0.072	0.024	0.886
07	0.054	0.862	0.006	0.078
08	0.796	0.03	0.078	0.096
09	0.012	0.892	0.054	0.042
10	0.012	0.88	0.018	0.09
11	0.545	0.168	0.018	0.269
12	0.198	0.0	0.802	0.0
13	0.024	0.018	0.03	0.928
14	0.569	0.03	0.401	0.0
15	0.904	0.06	0.012	0.024
16	0.94	0.0	0.054	0.006
17	0.425	0.192	0.293	0.09
18	0.006	0.982	0.012	0.0
19	0.03	0.844	0.0	0.126
20	0.82	0.078	0.072	0.03
21	0.006	0.12	0.036	0.838
22	0.06	0.832	0.006	0.102
23	0.347	0.006	0.138	0.509
24	0.036	0.0	0.958	0.006
25	0.042	0.006	0.916	0.036
26	0.06	0.024	0.647	0.269
27	0.006	0.988	0.0	0.006
28	0.006	0.946	0.006	0.042
29	0.114	0.108	0.024	0.754
30	0.156	0.012	0.76	0.072
31	0.126	0.0	0.856	0.018

PWM

	A	C	G	T
01	1.036	-1.339	-0.704	-0.856
02	-0.143	-1.648	0.959	-1.103
03	1.053	-1.339	-0.319	-1.925
04	1.153	-1.432	-1.339	-1.103
05	-0.972	-0.752	-1.432	1.069
06	-2.308	-1.176	-2.098	1.244
07	-1.432	1.217	-2.938	-1.103
08	1.138	-1.925	-1.103	-0.912
09	-2.574	1.251	-1.432	-1.648
10	-2.574	1.237	-2.308	-0.972
11	0.763	-0.385	-2.308	0.073
12	-0.227	-3.515	1.145	-3.515
13	-2.098	-2.308	-1.925	1.29
14	0.805	-1.925	0.462	-3.515
15	1.264	-1.339	-2.574	-2.098
16	1.302	-3.515	-1.432	-2.938
17	0.519	-0.257	0.156	-0.972
18	-2.938	1.346	-2.574	-3.515
19	-1.925	1.196	-3.515	-0.658
20	1.167	-1.103	-1.176	-1.925
21	-2.938	-0.704	-1.777	1.189
22	-1.339	1.182	-2.938	-0.856
23	0.32	-2.938	-0.572	0.696
24	-1.777	-3.515	1.321	-2.938
25	-1.648	-2.938	1.277	-1.777
26	-1.339	-2.098	0.932	0.073
27	-2.938	1.352	-3.515	-2.938
28	-2.938	1.309	-2.938	-1.648
29	-0.752	-0.803	-2.098	1.084
30	-0.456	-2.574	1.092	-1.176
31	-0.658	-3.515	1.21	-2.308

Standard thresholds

P-value	Threshold
0.001	-5.66714
0.0005	-3.98784
0.0001	-0.37694