| Motif | ZN454.H14CORE.0.P.B |
| Gene (human) | ZNF454 (GeneCards) |
| Gene synonyms (human) | |
| Gene (mouse) | |
| Gene synonyms (mouse) | |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 0 |
| Quality | B |
| Motif | ZN454.H14CORE.0.P.B |
| Gene (human) | ZNF454 (GeneCards) |
| Gene synonyms (human) | |
| Gene (mouse) | |
| Gene synonyms (mouse) | |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 0 |
| Quality | B |
| Motif length | 23 |
| Consensus | CYvhYdGRdSMYRRWKCYWTTYb |
| GC content | 53.46% |
| Information content (bits; total / per base) | 17.377 / 0.756 |
| Data sources | ChIP-Seq |
| Aligned words | 71 |
| Previous names | ZN454.H12CORE.0.P.B |
| ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Human | 2 (7) | 0.68 | 0.815 | 0.541 | 0.794 | 0.834 | 0.842 | 5.539 | 6.052 | 31.959 | 81.125 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Overall, 2 experiments | median | 0.543 | 0.531 | 0.526 | 0.521 | 0.512 | 0.512 |
| best | 0.627 | 0.582 | 0.587 | 0.56 | 0.552 | 0.541 | |
| Methyl HT-SELEX, 1 experiments | median | 0.46 | 0.479 | 0.465 | 0.481 | 0.471 | 0.484 |
| best | 0.46 | 0.479 | 0.465 | 0.481 | 0.471 | 0.484 | |
| Non-Methyl HT-SELEX, 1 experiments | median | 0.627 | 0.582 | 0.587 | 0.56 | 0.552 | 0.541 |
| best | 0.627 | 0.582 | 0.587 | 0.56 | 0.552 | 0.541 | |
| TF superclass | Zinc-coordinating DNA-binding domains {2} (TFClass) |
| TF class | C2H2 zinc finger factors {2.3} (TFClass) |
| TF family | More than 3 adjacent zinc fingers {2.3.3} (TFClass) |
| TF subfamily | Unclassified {2.3.3.0} (TFClass) |
| TFClass ID | TFClass: 2.3.3.0.125 |
| HGNC | HGNC:21200 |
| MGI | |
| EntrezGene (human) | GeneID:285676 (SSTAR profile) |
| EntrezGene (mouse) | |
| UniProt ID (human) | ZN454_HUMAN |
| UniProt ID (mouse) | |
| UniProt AC (human) | Q8N9F8 (TFClass) |
| UniProt AC (mouse) | |
| GRECO-DB-TF | yes |
| ChIP-Seq | 2 human, 0 mouse |
| HT-SELEX | 1 |
| Methyl-HT-SELEX | 1 |
| Genomic HT-SELEX | 0 overall: 0 Lysate, 0 IVT, 0 GFPIVT |
| SMiLE-Seq | 0 |
| PBM | 0 |
| PCM | ZN454.H14CORE.0.P.B.pcm |
| PWM | ZN454.H14CORE.0.P.B.pwm |
| PFM | ZN454.H14CORE.0.P.B.pfm |
| Threshold to P-value map | ZN454.H14CORE.0.P.B.thr |
| Motif in other formats | |
| JASPAR format | ZN454.H14CORE.0.P.B_jaspar_format.txt |
| MEME format | ZN454.H14CORE.0.P.B_meme_format.meme |
| Transfac format | ZN454.H14CORE.0.P.B_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 5.0 | 57.0 | 1.0 | 8.0 |
| 02 | 5.0 | 49.0 | 4.0 | 13.0 |
| 03 | 37.0 | 20.0 | 8.0 | 6.0 |
| 04 | 9.0 | 9.0 | 3.0 | 50.0 |
| 05 | 5.0 | 48.0 | 1.0 | 17.0 |
| 06 | 17.0 | 9.0 | 14.0 | 31.0 |
| 07 | 0.0 | 9.0 | 60.0 | 2.0 |
| 08 | 13.0 | 1.0 | 48.0 | 9.0 |
| 09 | 11.0 | 6.0 | 41.0 | 13.0 |
| 10 | 1.0 | 47.0 | 22.0 | 1.0 |
| 11 | 19.0 | 44.0 | 0.0 | 8.0 |
| 12 | 2.0 | 14.0 | 5.0 | 50.0 |
| 13 | 15.0 | 2.0 | 47.0 | 7.0 |
| 14 | 23.0 | 2.0 | 45.0 | 1.0 |
| 15 | 30.0 | 2.0 | 6.0 | 33.0 |
| 16 | 3.0 | 1.0 | 40.0 | 27.0 |
| 17 | 6.0 | 58.0 | 3.0 | 4.0 |
| 18 | 1.0 | 50.0 | 3.0 | 17.0 |
| 19 | 29.0 | 1.0 | 2.0 | 39.0 |
| 20 | 3.0 | 1.0 | 1.0 | 66.0 |
| 21 | 2.0 | 13.0 | 0.0 | 56.0 |
| 22 | 0.0 | 22.0 | 6.0 | 43.0 |
| 23 | 5.0 | 21.0 | 27.0 | 18.0 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.07 | 0.803 | 0.014 | 0.113 |
| 02 | 0.07 | 0.69 | 0.056 | 0.183 |
| 03 | 0.521 | 0.282 | 0.113 | 0.085 |
| 04 | 0.127 | 0.127 | 0.042 | 0.704 |
| 05 | 0.07 | 0.676 | 0.014 | 0.239 |
| 06 | 0.239 | 0.127 | 0.197 | 0.437 |
| 07 | 0.0 | 0.127 | 0.845 | 0.028 |
| 08 | 0.183 | 0.014 | 0.676 | 0.127 |
| 09 | 0.155 | 0.085 | 0.577 | 0.183 |
| 10 | 0.014 | 0.662 | 0.31 | 0.014 |
| 11 | 0.268 | 0.62 | 0.0 | 0.113 |
| 12 | 0.028 | 0.197 | 0.07 | 0.704 |
| 13 | 0.211 | 0.028 | 0.662 | 0.099 |
| 14 | 0.324 | 0.028 | 0.634 | 0.014 |
| 15 | 0.423 | 0.028 | 0.085 | 0.465 |
| 16 | 0.042 | 0.014 | 0.563 | 0.38 |
| 17 | 0.085 | 0.817 | 0.042 | 0.056 |
| 18 | 0.014 | 0.704 | 0.042 | 0.239 |
| 19 | 0.408 | 0.014 | 0.028 | 0.549 |
| 20 | 0.042 | 0.014 | 0.014 | 0.93 |
| 21 | 0.028 | 0.183 | 0.0 | 0.789 |
| 22 | 0.0 | 0.31 | 0.085 | 0.606 |
| 23 | 0.07 | 0.296 | 0.38 | 0.254 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | -1.132 | 1.127 | -2.209 | -0.73 |
| 02 | -1.132 | 0.979 | -1.312 | -0.291 |
| 03 | 0.705 | 0.113 | -0.73 | -0.979 |
| 04 | -0.626 | -0.626 | -1.532 | 0.998 |
| 05 | -1.132 | 0.958 | -2.209 | -0.041 |
| 06 | -0.041 | -0.626 | -0.222 | 0.533 |
| 07 | -2.871 | -0.626 | 1.177 | -1.814 |
| 08 | -0.291 | -2.209 | 0.958 | -0.626 |
| 09 | -0.444 | -0.979 | 0.805 | -0.291 |
| 10 | -2.209 | 0.938 | 0.204 | -2.209 |
| 11 | 0.064 | 0.873 | -2.871 | -0.73 |
| 12 | -1.814 | -0.222 | -1.132 | 0.998 |
| 13 | -0.158 | -1.814 | 0.938 | -0.847 |
| 14 | 0.246 | -1.814 | 0.895 | -2.209 |
| 15 | 0.501 | -1.814 | -0.979 | 0.594 |
| 16 | -1.532 | -2.209 | 0.78 | 0.4 |
| 17 | -0.979 | 1.144 | -1.532 | -1.312 |
| 18 | -2.209 | 0.998 | -1.532 | -0.041 |
| 19 | 0.469 | -2.209 | -1.814 | 0.756 |
| 20 | -1.532 | -2.209 | -2.209 | 1.271 |
| 21 | -1.814 | -0.291 | -2.871 | 1.11 |
| 22 | -2.871 | 0.204 | -0.979 | 0.851 |
| 23 | -1.132 | 0.159 | 0.4 | 0.013 |
| P-value | Threshold |
|---|---|
| 0.001 | 3.32276 |
| 0.0005 | 4.35676 |
| 0.0001 | 6.54831 |