ZN395.H14RSNP.0.PSGI.D motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ZN395.H14RSNP.0.PSGI.D
Gene (human)	ZNF395 (GeneCards)
Gene synonyms (human)
Gene (mouse)
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	D

Motif length	10
Consensus	SCGGCCGGCn
GC content	88.6%
Information content (bits; total / per base)	13.299 / 1.33
Data sources	ChIP-Seq + HT-SELEX + Genomic HT-SELEX + SMiLe-Seq
Aligned words	916
Previous names

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	Centrality, median	Centrality, best
Overall	1 (2)	0.837	0.841	0.71	0.714	0.625	0.643	24.325	40.796

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
overall, 5 experiments	median	1.0	1.0	0.999	0.998	0.935	0.948
overall, 5 experiments	best	1.0	1.0	1.0	1.0	0.998	0.997
Lysate, 2 experiments	median	1.0	1.0	0.999	0.998	0.811	0.851
Lysate, 2 experiments	best	1.0	1.0	0.999	0.998	0.812	0.851
IVT, 1 experiments	median	0.999	0.998	0.997	0.996	0.985	0.982
IVT, 1 experiments	best	0.999	0.998	0.997	0.996	0.985	0.982
GFPIVT, 2 experiments	median	1.0	1.0	1.0	1.0	0.967	0.972
GFPIVT, 2 experiments	best	1.0	1.0	1.0	1.0	0.998	0.997

Genomic HT-SELEX benchmarking		Centrality	pseudo-auROC	auROC	auPR
overall, 5 experiments	median	305.194	0.812	0.916	0.882
overall, 5 experiments	best	558.745	0.895	0.959	0.938
Lysate, 2 experiments	median	431.651	0.836	0.938	0.885
Lysate, 2 experiments	best	558.108	0.859	0.959	0.929
IVT, 1 experiments	median	197.076	0.678	0.883	0.784
IVT, 1 experiments	best	197.076	0.678	0.883	0.784
GFPIVT, 2 experiments	median	266.546	0.811	0.923	0.892
GFPIVT, 2 experiments	best	558.745	0.895	0.952	0.938

SMiLE-Seq benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 2 experiments	median	0.722	0.698	0.63	0.62	0.572	0.575
Overall, 2 experiments	best	0.776	0.748	0.674	0.657	0.596	0.599

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	Other with up to three adjacent zinc fingers {2.3.2} (TFClass)
TF subfamily	CR1-CR2 {2.3.2.255} (TFClass)
TFClass ID	TFClass: 2.3.2.255.2
HGNC
MGI
EntrezGene (human)
EntrezGene (mouse)
UniProt ID (human)	ZN395_HUMAN
UniProt ID (mouse)
UniProt AC (human)	Q9H8N7 (TFClass)
UniProt AC (mouse)
GRECO-DB-TF	yes

ChIP-Seq	1 human, 0 mouse
HT-SELEX	5 overall: 2 Lysate, 1 IVT, 2 GFPIVT
Genomic HT-SELEX	5 overall: 2 Lysate, 1 IVT, 2 GFPIVT
SMiLE-Seq	2
PBM	0

PCM	ZN395.H14RSNP.0.PSGI.D.pcm
PWM	ZN395.H14RSNP.0.PSGI.D.pwm
PFM	ZN395.H14RSNP.0.PSGI.D.pfm
Threshold to P-value map	ZN395.H14RSNP.0.PSGI.D.thr
Motif in other formats
JASPAR format	ZN395.H14RSNP.0.PSGI.D_jaspar_format.txt
MEME format	ZN395.H14RSNP.0.PSGI.D_meme_format.meme
Transfac format	ZN395.H14RSNP.0.PSGI.D_transfac_format.txt
Homer format	ZN395.H14RSNP.0.PSGI.D_homer_format_0.001.txt ZN395.H14RSNP.0.PSGI.D_homer_format_0.0005.txt ZN395.H14RSNP.0.PSGI.D_homer_format_0.0001.txt

PCM

	A	C	G	T
01	14.0	646.0	236.0	20.0
02	60.0	825.0	15.0	16.0
03	33.0	5.0	746.0	132.0
04	22.0	151.0	741.0	2.0
05	6.0	902.0	1.0	7.0
06	2.0	910.0	2.0	2.0
07	2.0	3.0	908.0	3.0
08	0.0	37.0	878.0	1.0
09	10.0	740.0	26.0	140.0
10	338.0	140.0	204.0	234.0

PFM

	A	C	G	T
01	0.015	0.705	0.258	0.022
02	0.066	0.901	0.016	0.017
03	0.036	0.005	0.814	0.144
04	0.024	0.165	0.809	0.002
05	0.007	0.985	0.001	0.008
06	0.002	0.993	0.002	0.002
07	0.002	0.003	0.991	0.003
08	0.0	0.04	0.959	0.001
09	0.011	0.808	0.028	0.153
10	0.369	0.153	0.223	0.255

PWM

	A	C	G	T
01	-2.687	1.032	0.03	-2.364
02	-1.319	1.276	-2.625	-2.567
03	-1.894	-3.538	1.176	-0.546
04	-2.275	-0.413	1.169	-4.131
05	-3.399	1.365	-4.446	-3.277
06	-4.131	1.374	-4.131	-4.131
07	-4.131	-3.893	1.372	-3.893
08	-4.908	-1.785	1.338	-4.446
09	-2.981	1.168	-2.12	-0.487
10	0.387	-0.487	-0.115	0.021

Standard thresholds

P-value	Threshold
0.001	3.387815
0.0005	4.58028
0.0001	6.99656