ZN362.H14RSNP.0.PSGI.D motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ZN362.H14RSNP.0.PSGI.D
Gene (human)	ZNF362 (GeneCards)
Gene synonyms (human)
Gene (mouse)
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	D

Motif length	11
Consensus	RAAAAAAAYnn
GC content	19.1%
Information content (bits; total / per base)	14.881 / 1.353
Data sources	ChIP-Seq + HT-SELEX + Genomic HT-SELEX + SMiLe-Seq
Aligned words	9557
Previous names

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	Centrality, median	Centrality, best
Overall	2 (4)	0.925	0.928	0.794	0.802	0.917	0.924	176.038	233.432

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
overall, 4 experiments	median	0.979	0.966	0.972	0.954	0.966	0.944
overall, 4 experiments	best	0.985	0.977	0.979	0.966	0.972	0.955
Lysate, 2 experiments	median	0.982	0.972	0.976	0.96	0.968	0.949
Lysate, 2 experiments	best	0.985	0.977	0.979	0.966	0.972	0.955
IVT, 1 experiments	median	0.923	0.913	0.66	0.71	0.559	0.612
IVT, 1 experiments	best	0.923	0.913	0.66	0.71	0.559	0.612
GFPIVT, 1 experiments	median	0.979	0.966	0.972	0.953	0.967	0.944
GFPIVT, 1 experiments	best	0.979	0.966	0.972	0.953	0.967	0.944

Genomic HT-SELEX benchmarking		Centrality	pseudo-auROC	auROC	auPR
overall, 4 experiments	median	61.796	0.92	0.907	0.856
overall, 4 experiments	best	89.009	0.942	0.94	0.884
Lysate, 2 experiments	median	64.992	0.931	0.924	0.831
Lysate, 2 experiments	best	68.187	0.942	0.94	0.884
IVT, 1 experiments	median	31.215	0.874	0.818	0.695
IVT, 1 experiments	best	31.215	0.874	0.818	0.695
GFPIVT, 1 experiments	median	65.548	0.923	0.914	0.869
GFPIVT, 1 experiments	best	89.009	0.927	0.927	0.881

SMiLE-Seq benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 3 experiments	median	0.7	0.686	0.577	0.593	0.533	0.551
Overall, 3 experiments	best	0.945	0.91	0.94	0.898	0.784	0.792

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	More than 3 adjacent zinc fingers {2.3.3} (TFClass)
TF subfamily	ZNF362-like {2.3.3.37} (TFClass)
TFClass ID	TFClass: 2.3.3.37.1
HGNC	HGNC:18079
MGI
EntrezGene (human)	GeneID:149076 (SSTAR profile)
EntrezGene (mouse)
UniProt ID (human)	ZN362_HUMAN
UniProt ID (mouse)
UniProt AC (human)	Q5T0B9 (TFClass)
UniProt AC (mouse)
GRECO-DB-TF	yes

ChIP-Seq	2 human, 0 mouse
HT-SELEX	4 overall: 2 Lysate, 1 IVT, 1 GFPIVT
Genomic HT-SELEX	4 overall: 2 Lysate, 1 IVT, 1 GFPIVT
SMiLE-Seq	3
PBM	0

PCM	ZN362.H14RSNP.0.PSGI.D.pcm
PWM	ZN362.H14RSNP.0.PSGI.D.pwm
PFM	ZN362.H14RSNP.0.PSGI.D.pfm
Threshold to P-value map	ZN362.H14RSNP.0.PSGI.D.thr
Motif in other formats
JASPAR format	ZN362.H14RSNP.0.PSGI.D_jaspar_format.txt
MEME format	ZN362.H14RSNP.0.PSGI.D_meme_format.meme
Transfac format	ZN362.H14RSNP.0.PSGI.D_transfac_format.txt
Homer format	ZN362.H14RSNP.0.PSGI.D_homer_format_0.001.txt ZN362.H14RSNP.0.PSGI.D_homer_format_0.0005.txt ZN362.H14RSNP.0.PSGI.D_homer_format_0.0001.txt

PCM

	A	C	G	T
01	6217.0	241.0	1596.0	1503.0
02	8935.0	43.0	332.0	247.0
03	9538.0	3.0	10.0	6.0
04	9554.0	1.0	0.0	2.0
05	9557.0	0.0	0.0	0.0
06	9556.0	0.0	1.0	0.0
07	9481.0	69.0	4.0	3.0
08	9555.0	0.0	2.0	0.0
09	32.0	6190.0	1604.0	1731.0
10	2721.75	1318.75	3238.75	2277.75
11	1469.25	3094.25	2336.25	2657.25

PFM

	A	C	G	T
01	0.651	0.025	0.167	0.157
02	0.935	0.004	0.035	0.026
03	0.998	0.0	0.001	0.001
04	1.0	0.0	0.0	0.0
05	1.0	0.0	0.0	0.0
06	1.0	0.0	0.0	0.0
07	0.992	0.007	0.0	0.0
08	1.0	0.0	0.0	0.0
09	0.003	0.648	0.168	0.181
10	0.285	0.138	0.339	0.238
11	0.154	0.324	0.244	0.278

PWM

	A	C	G	T
01	0.956	-2.285	-0.403	-0.463
02	1.318	-3.967	-1.968	-2.261
03	1.384	-6.114	-5.271	-5.664
04	1.385	-6.588	-6.951	-6.323
05	1.386	-6.951	-6.951	-6.951
06	1.385	-6.951	-6.588	-6.951
07	1.378	-3.513	-5.941	-6.114
08	1.385	-6.951	-6.323	-6.951
09	-4.245	0.951	-0.398	-0.322
10	0.13	-0.594	0.304	-0.048
11	-0.486	0.258	-0.022	0.106

Standard thresholds

P-value	Threshold
0.001	0.20208
0.0005	2.004865
0.0001	5.749885