ZN362.H14INVIVO.0.PSGI.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ZN362.H14INVIVO.0.PSGI.A
Gene (human)	ZNF362 (GeneCards)
Gene synonyms (human)
Gene (mouse)
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	A

Motif length	19
Consensus	nnKAAAAAAAAAMnvhhnh
GC content	23.12%
Information content (bits; total / per base)	18.249 / 0.96
Data sources	ChIP-Seq + HT-SELEX + Genomic HT-SELEX + SMiLe-Seq
Aligned words	423
Previous names

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	Centrality, median	Centrality, best
Overall	2 (4)	0.966	0.968	0.904	0.912	0.989	0.992	234.765	300.387

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
overall, 4 experiments	median	0.926	0.868	0.938	0.879	0.934	0.881
overall, 4 experiments	best	0.94	0.878	0.949	0.898	0.939	0.893
Lysate, 2 experiments	median	0.931	0.863	0.942	0.886	0.935	0.884
Lysate, 2 experiments	best	0.94	0.878	0.949	0.898	0.939	0.893
IVT, 1 experiments	median	0.89	0.873	0.644	0.688	0.554	0.6
IVT, 1 experiments	best	0.89	0.873	0.644	0.688	0.554	0.6
GFPIVT, 1 experiments	median	0.929	0.863	0.941	0.884	0.937	0.886
GFPIVT, 1 experiments	best	0.929	0.863	0.941	0.884	0.937	0.886

Genomic HT-SELEX benchmarking		Centrality	pseudo-auROC	auROC	auPR
overall, 4 experiments	median	63.208	0.967	0.923	0.8
overall, 4 experiments	best	102.523	0.988	0.933	0.859
Lysate, 2 experiments	median	67.223	0.986	0.927	0.81
Lysate, 2 experiments	best	71.237	0.988	0.93	0.82
IVT, 1 experiments	median	35.495	0.906	0.876	0.787
IVT, 1 experiments	best	35.495	0.906	0.876	0.787
GFPIVT, 1 experiments	median	75.66	0.962	0.915	0.815
GFPIVT, 1 experiments	best	102.523	0.967	0.933	0.859

SMiLE-Seq benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 3 experiments	median	0.672	0.656	0.566	0.579	0.521	0.541
Overall, 3 experiments	best	0.924	0.85	0.909	0.85	0.739	0.742

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	More than 3 adjacent zinc fingers {2.3.3} (TFClass)
TF subfamily	ZNF362-like {2.3.3.37} (TFClass)
TFClass ID	TFClass: 2.3.3.37.1
HGNC	HGNC:18079
MGI
EntrezGene (human)	GeneID:149076 (SSTAR profile)
EntrezGene (mouse)
UniProt ID (human)	ZN362_HUMAN
UniProt ID (mouse)
UniProt AC (human)	Q5T0B9 (TFClass)
UniProt AC (mouse)
GRECO-DB-TF	yes

ChIP-Seq	2 human, 0 mouse
HT-SELEX	4 overall: 2 Lysate, 1 IVT, 1 GFPIVT
Genomic HT-SELEX	4 overall: 2 Lysate, 1 IVT, 1 GFPIVT
SMiLE-Seq	3
PBM	0

PCM	ZN362.H14INVIVO.0.PSGI.A.pcm
PWM	ZN362.H14INVIVO.0.PSGI.A.pwm
PFM	ZN362.H14INVIVO.0.PSGI.A.pfm
Threshold to P-value map	ZN362.H14INVIVO.0.PSGI.A.thr
Motif in other formats
JASPAR format	ZN362.H14INVIVO.0.PSGI.A_jaspar_format.txt
MEME format	ZN362.H14INVIVO.0.PSGI.A_meme_format.meme
Transfac format	ZN362.H14INVIVO.0.PSGI.A_transfac_format.txt
Homer format	ZN362.H14INVIVO.0.PSGI.A_homer_format_0.001.txt ZN362.H14INVIVO.0.PSGI.A_homer_format_0.0005.txt ZN362.H14INVIVO.0.PSGI.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	112.5	90.5	111.5	108.5
02	78.75	130.75	92.75	120.75
03	0.0	102.0	167.0	154.0
04	422.0	0.0	1.0	0.0
05	404.0	8.0	2.0	9.0
06	418.0	1.0	0.0	4.0
07	423.0	0.0	0.0	0.0
08	423.0	0.0	0.0	0.0
09	423.0	0.0	0.0	0.0
10	422.0	0.0	1.0	0.0
11	412.0	8.0	2.0	1.0
12	348.0	50.0	15.0	10.0
13	272.0	74.0	45.0	32.0
14	217.0	88.0	59.0	59.0
15	170.0	93.0	81.0	79.0
16	173.0	87.0	74.0	89.0
17	202.0	73.0	63.0	85.0
18	178.5	109.5	67.5	67.5
19	174.75	93.75	67.75	86.75

PFM

	A	C	G	T
01	0.266	0.214	0.264	0.257
02	0.186	0.309	0.219	0.285
03	0.0	0.241	0.395	0.364
04	0.998	0.0	0.002	0.0
05	0.955	0.019	0.005	0.021
06	0.988	0.002	0.0	0.009
07	1.0	0.0	0.0	0.0
08	1.0	0.0	0.0	0.0
09	1.0	0.0	0.0	0.0
10	0.998	0.0	0.002	0.0
11	0.974	0.019	0.005	0.002
12	0.823	0.118	0.035	0.024
13	0.643	0.175	0.106	0.076
14	0.513	0.208	0.139	0.139
15	0.402	0.22	0.191	0.187
16	0.409	0.206	0.175	0.21
17	0.478	0.173	0.149	0.201
18	0.422	0.259	0.16	0.16
19	0.413	0.222	0.16	0.205

PWM

	A	C	G	T
01	0.061	-0.153	0.052	0.025
02	-0.29	0.21	-0.129	0.131
03	-4.262	-0.036	0.452	0.371
04	1.373	-4.262	-3.754	-4.262
05	1.33	-2.423	-3.419	-2.323
06	1.364	-3.754	-4.262	-2.968
07	1.376	-4.262	-4.262	-4.262
08	1.376	-4.262	-4.262	-4.262
09	1.376	-4.262	-4.262	-4.262
10	1.373	-4.262	-3.754	-4.262
11	1.349	-2.423	-3.419	-3.754
12	1.181	-0.733	-1.871	-2.232
13	0.936	-0.351	-0.836	-1.163
14	0.712	-0.181	-0.572	-0.572
15	0.469	-0.127	-0.262	-0.287
16	0.487	-0.192	-0.351	-0.17
17	0.64	-0.364	-0.508	-0.215
18	0.518	0.034	-0.441	-0.441
19	0.497	-0.119	-0.437	-0.195

Standard thresholds

P-value	Threshold
0.001	0.54551
0.0005	2.02381
0.0001	5.21466