ZN292.H14INVIVO.0.PSG.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ZN292.H14INVIVO.0.PSG.A
Gene (human)	ZNF292 (GeneCards)
Gene synonyms (human)	KIAA0530
Gene (mouse)	Zfp292
Gene synonyms (mouse)	Zfp15
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	A

Motif length	18
Consensus	bYbvhdGCTGCWKhbbbb
GC content	57.46%
Information content (bits; total / per base)	12.233 / 0.68
Data sources	ChIP-Seq + HT-SELEX + Genomic HT-SELEX
Aligned words	190
Previous names

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	Centrality, median	Centrality, best
Overall	2 (2)	0.793	0.828	0.674	0.728	0.703	0.723	6.242	7.276

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
overall, 3 experiments	median	0.636	0.587	0.613	0.572	0.593	0.559
overall, 3 experiments	best	0.933	0.886	0.899	0.851	0.823	0.786
IVT, 1 experiments	median	0.63	0.581	0.613	0.57	0.593	0.559
IVT, 1 experiments	best	0.63	0.581	0.613	0.57	0.593	0.559
GFPIVT, 2 experiments	median	0.785	0.736	0.756	0.712	0.704	0.672
GFPIVT, 2 experiments	best	0.933	0.886	0.899	0.851	0.823	0.786

Genomic HT-SELEX benchmarking		Centrality	pseudo-auROC	auROC	auPR
overall, 3 experiments	median	0.0	0.4	0.492	0.368
overall, 3 experiments	best	47.678	0.617	0.701	0.526
IVT, 1 experiments	median	0.0	0.4	0.391	0.287
IVT, 1 experiments	best	0.0	0.4	0.391	0.287
GFPIVT, 2 experiments	median	6.829	0.434	0.549	0.406
GFPIVT, 2 experiments	best	47.678	0.617	0.701	0.526

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	Multiple dispersed zinc fingers {2.3.4} (TFClass)
TF subfamily	RLF-like {2.3.4.7} (TFClass)
TFClass ID	TFClass: 2.3.4.7.2
HGNC	HGNC:18410
MGI	MGI:1353423
EntrezGene (human)	GeneID:23036 (SSTAR profile)
EntrezGene (mouse)	GeneID:30046 (SSTAR profile)
UniProt ID (human)	ZN292_HUMAN
UniProt ID (mouse)	ZN292_MOUSE
UniProt AC (human)	O60281 (TFClass)
UniProt AC (mouse)	Q9Z2U2 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	2 human, 0 mouse
HT-SELEX	3 overall: 0 Lysate, 1 IVT, 2 GFPIVT
Genomic HT-SELEX	3 overall: 0 Lysate, 1 IVT, 2 GFPIVT
SMiLE-Seq	0
PBM	0

PCM	ZN292.H14INVIVO.0.PSG.A.pcm
PWM	ZN292.H14INVIVO.0.PSG.A.pwm
PFM	ZN292.H14INVIVO.0.PSG.A.pfm
Threshold to P-value map	ZN292.H14INVIVO.0.PSG.A.thr
Motif in other formats
JASPAR format	ZN292.H14INVIVO.0.PSG.A_jaspar_format.txt
MEME format	ZN292.H14INVIVO.0.PSG.A_meme_format.meme
Transfac format	ZN292.H14INVIVO.0.PSG.A_transfac_format.txt
Homer format	ZN292.H14INVIVO.0.PSG.A_homer_format_0.001.txt ZN292.H14INVIVO.0.PSG.A_homer_format_0.0005.txt ZN292.H14INVIVO.0.PSG.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	14.0	64.0	33.0	79.0
02	8.0	61.0	19.0	102.0
03	15.0	70.0	37.0	68.0
04	20.0	105.0	46.0	19.0
05	53.0	92.0	14.0	31.0
06	44.0	8.0	89.0	49.0
07	3.0	6.0	159.0	22.0
08	1.0	178.0	8.0	3.0
09	14.0	1.0	0.0	175.0
10	0.0	3.0	182.0	5.0
11	2.0	177.0	4.0	7.0
12	58.0	13.0	3.0	116.0
13	5.0	7.0	119.0	59.0
14	34.0	46.0	22.0	88.0
15	9.0	55.0	82.0	44.0
16	9.0	35.0	59.0	87.0
17	8.0	73.0	25.0	84.0
18	19.0	34.0	36.0	101.0

PFM

	A	C	G	T
01	0.074	0.337	0.174	0.416
02	0.042	0.321	0.1	0.537
03	0.079	0.368	0.195	0.358
04	0.105	0.553	0.242	0.1
05	0.279	0.484	0.074	0.163
06	0.232	0.042	0.468	0.258
07	0.016	0.032	0.837	0.116
08	0.005	0.937	0.042	0.016
09	0.074	0.005	0.0	0.921
10	0.0	0.016	0.958	0.026
11	0.011	0.932	0.021	0.037
12	0.305	0.068	0.016	0.611
13	0.026	0.037	0.626	0.311
14	0.179	0.242	0.116	0.463
15	0.047	0.289	0.432	0.232
16	0.047	0.184	0.311	0.458
17	0.042	0.384	0.132	0.442
18	0.1	0.179	0.189	0.532

PWM

	A	C	G	T
01	-1.159	0.291	-0.352	0.498
02	-1.657	0.244	-0.877	0.75
03	-1.096	0.379	-0.242	0.351
04	-0.829	0.778	-0.031	-0.877
05	0.107	0.648	-1.159	-0.413
06	-0.074	-1.657	0.615	0.03
07	-2.427	-1.898	1.189	-0.739
08	-3.05	1.301	-1.657	-2.427
09	-1.159	-3.05	-3.617	1.284
10	-3.617	-2.427	1.323	-2.046
11	-2.69	1.296	-2.218	-1.77
12	0.195	-1.227	-2.427	0.877
13	-2.046	-1.77	0.902	0.212
14	-0.324	-0.031	-0.739	0.604
15	-1.555	0.143	0.535	-0.074
16	-1.555	-0.296	0.212	0.593
17	-1.657	0.42	-0.618	0.558
18	-0.877	-0.324	-0.269	0.74

Standard thresholds

P-value	Threshold
0.001	4.32181
0.0005	5.24216
0.0001	7.15186