ZN251.H14INVIVO.0.PSGI.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ZN251.H14INVIVO.0.PSGI.A
Gene (human)	ZNF251 (GeneCards)
Gene synonyms (human)
Gene (mouse)
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	A

Motif length	21
Consensus	hbKCdSTbARCRChbhnnYhb
GC content	54.52%
Information content (bits; total / per base)	12.349 / 0.588
Data sources	ChIP-Seq + HT-SELEX + Genomic HT-SELEX + SMiLe-Seq
Aligned words	174
Previous names

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	Centrality, median	Centrality, best
Overall	2 (4)	0.964	0.967	0.948	0.951	0.903	0.919	322.273	334.06

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
GFPIVT, 2 experiments	median	1.0	1.0	0.999	0.999	0.994	0.993
GFPIVT, 2 experiments	best	1.0	1.0	0.999	0.999	0.996	0.995

Genomic HT-SELEX benchmarking		Centrality	pseudo-auROC	auROC	auPR
GFPIVT, 2 experiments	median	688.013	0.865	0.944	0.937
GFPIVT, 2 experiments	best	900.658	0.967	0.983	0.976

SMiLE-Seq benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 1 experiments	median	0.827	0.784	0.679	0.673	0.586	0.602
Overall, 1 experiments	best	0.827	0.784	0.679	0.673	0.586	0.602

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	Multiple dispersed zinc fingers {2.3.4} (TFClass)
TF subfamily	Unclassified {2.3.4.0} (TFClass)
TFClass ID	TFClass: 2.3.4.0.52
HGNC	HGNC:13045
MGI
EntrezGene (human)	GeneID:90987 (SSTAR profile)
EntrezGene (mouse)
UniProt ID (human)	ZN251_HUMAN
UniProt ID (mouse)
UniProt AC (human)	Q9BRH9 (TFClass)
UniProt AC (mouse)
GRECO-DB-TF	yes

ChIP-Seq	2 human, 0 mouse
HT-SELEX	2 overall: 0 Lysate, 0 IVT, 2 GFPIVT
Genomic HT-SELEX	2 overall: 0 Lysate, 0 IVT, 2 GFPIVT
SMiLE-Seq	1
PBM	0

PCM	ZN251.H14INVIVO.0.PSGI.A.pcm
PWM	ZN251.H14INVIVO.0.PSGI.A.pwm
PFM	ZN251.H14INVIVO.0.PSGI.A.pfm
Threshold to P-value map	ZN251.H14INVIVO.0.PSGI.A.thr
Motif in other formats
JASPAR format	ZN251.H14INVIVO.0.PSGI.A_jaspar_format.txt
MEME format	ZN251.H14INVIVO.0.PSGI.A_meme_format.meme
Transfac format	ZN251.H14INVIVO.0.PSGI.A_transfac_format.txt
Homer format	ZN251.H14INVIVO.0.PSGI.A_homer_format_0.001.txt ZN251.H14INVIVO.0.PSGI.A_homer_format_0.0005.txt ZN251.H14INVIVO.0.PSGI.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	29.0	32.0	21.0	92.0
02	24.0	29.0	34.0	87.0
03	10.0	12.0	99.0	53.0
04	4.0	154.0	10.0	6.0
05	87.0	20.0	40.0	27.0
06	1.0	108.0	49.0	16.0
07	4.0	7.0	1.0	162.0
08	15.0	28.0	30.0	101.0
09	140.0	0.0	27.0	7.0
10	40.0	8.0	121.0	5.0
11	4.0	164.0	3.0	3.0
12	44.0	6.0	121.0	3.0
13	7.0	149.0	6.0	12.0
14	40.0	77.0	18.0	39.0
15	10.0	55.0	59.0	50.0
16	38.0	22.0	17.0	97.0
17	35.0	51.0	33.0	55.0
18	25.0	41.0	44.0	64.0
19	18.0	115.0	16.0	25.0
20	43.0	64.0	16.0	51.0
21	23.0	46.0	39.0	66.0

PFM

	A	C	G	T
01	0.167	0.184	0.121	0.529
02	0.138	0.167	0.195	0.5
03	0.057	0.069	0.569	0.305
04	0.023	0.885	0.057	0.034
05	0.5	0.115	0.23	0.155
06	0.006	0.621	0.282	0.092
07	0.023	0.04	0.006	0.931
08	0.086	0.161	0.172	0.58
09	0.805	0.0	0.155	0.04
10	0.23	0.046	0.695	0.029
11	0.023	0.943	0.017	0.017
12	0.253	0.034	0.695	0.017
13	0.04	0.856	0.034	0.069
14	0.23	0.443	0.103	0.224
15	0.057	0.316	0.339	0.287
16	0.218	0.126	0.098	0.557
17	0.201	0.293	0.19	0.316
18	0.144	0.236	0.253	0.368
19	0.103	0.661	0.092	0.144
20	0.247	0.368	0.092	0.293
21	0.132	0.264	0.224	0.379

PWM

	A	C	G	T
01	-0.391	-0.297	-0.698	0.734
02	-0.572	-0.391	-0.238	0.679
03	-1.378	-1.215	0.806	0.192
04	-2.136	1.243	-1.378	-1.816
05	0.679	-0.744	-0.081	-0.459
06	-2.974	0.892	0.116	-0.952
07	-2.136	-1.687	-2.974	1.294
08	-1.011	-0.425	-0.359	0.826
09	1.149	-3.548	-0.459	-1.687
10	-0.081	-1.573	1.004	-1.963
11	-2.136	1.306	-2.346	-2.346
12	0.011	-1.816	1.004	-2.346
13	-1.687	1.211	-1.816	-1.215
14	-0.081	0.558	-0.842	-0.106
15	-1.378	0.229	0.297	0.136
16	-0.131	-0.654	-0.896	0.786
17	-0.21	0.155	-0.267	0.229
18	-0.533	-0.057	0.011	0.377
19	-0.842	0.954	-0.952	-0.533
20	-0.011	0.377	-0.952	0.155
21	-0.612	0.054	-0.106	0.407

Standard thresholds

P-value	Threshold
0.001	4.32506
0.0005	5.21211
0.0001	7.07361