ZN226.H14INVIVO.0.PSGI.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ZN226.H14INVIVO.0.PSGI.A
Gene (human)	ZNF226 (GeneCards)
Gene synonyms (human)
Gene (mouse)
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	A

Motif length	25
Consensus	vRWnWKAWWhAWRGGMARnMhvndv
GC content	36.88%
Information content (bits; total / per base)	16.518 / 0.661
Data sources	ChIP-Seq + HT-SELEX + Genomic HT-SELEX + SMiLe-Seq
Aligned words	95
Previous names

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	Centrality, median	Centrality, best
Overall	1 (2)	0.722	0.749	0.718	0.744	0.785	0.813	29.368	41.409

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
GFPIVT, 2 experiments	median	0.909	0.914	0.809	0.829	0.73	0.755
GFPIVT, 2 experiments	best	0.999	0.999	0.995	0.993	0.922	0.924

Genomic HT-SELEX benchmarking		Centrality	pseudo-auROC	auROC	auPR
GFPIVT, 2 experiments	median	289.281	0.807	0.758	0.706
GFPIVT, 2 experiments	best	377.678	0.817	0.78	0.747

SMiLE-Seq benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 1 experiments	median	0.602	0.588	0.534	0.543	0.508	0.521
Overall, 1 experiments	best	0.602	0.588	0.534	0.543	0.508	0.521

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	More than 3 adjacent zinc fingers {2.3.3} (TFClass)
TF subfamily	ZNF222-like {2.3.3.47} (TFClass)
TFClass ID	TFClass: 2.3.3.47.13
HGNC	HGNC:13019
MGI
EntrezGene (human)	GeneID:7769 (SSTAR profile)
EntrezGene (mouse)
UniProt ID (human)	ZN226_HUMAN
UniProt ID (mouse)
UniProt AC (human)	Q9NYT6 (TFClass)
UniProt AC (mouse)
GRECO-DB-TF	yes

ChIP-Seq	1 human, 0 mouse
HT-SELEX	2 overall: 0 Lysate, 0 IVT, 2 GFPIVT
Genomic HT-SELEX	2 overall: 0 Lysate, 0 IVT, 2 GFPIVT
SMiLE-Seq	1
PBM	0

PCM	ZN226.H14INVIVO.0.PSGI.A.pcm
PWM	ZN226.H14INVIVO.0.PSGI.A.pwm
PFM	ZN226.H14INVIVO.0.PSGI.A.pfm
Threshold to P-value map	ZN226.H14INVIVO.0.PSGI.A.thr
Motif in other formats
JASPAR format	ZN226.H14INVIVO.0.PSGI.A_jaspar_format.txt
MEME format	ZN226.H14INVIVO.0.PSGI.A_meme_format.meme
Transfac format	ZN226.H14INVIVO.0.PSGI.A_transfac_format.txt
Homer format	ZN226.H14INVIVO.0.PSGI.A_homer_format_0.001.txt ZN226.H14INVIVO.0.PSGI.A_homer_format_0.0005.txt ZN226.H14INVIVO.0.PSGI.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	64.0	13.0	13.0	5.0
02	66.0	4.0	22.0	3.0
03	20.0	6.0	8.0	61.0
04	31.0	22.0	15.0	27.0
05	55.0	4.0	5.0	31.0
06	8.0	4.0	71.0	12.0
07	81.0	6.0	8.0	0.0
08	9.0	6.0	5.0	75.0
09	65.0	3.0	8.0	19.0
10	39.0	35.0	7.0	14.0
11	86.0	2.0	6.0	1.0
12	16.0	12.0	9.0	58.0
13	56.0	0.0	33.0	6.0
14	8.0	0.0	86.0	1.0
15	11.0	1.0	83.0	0.0
16	65.0	22.0	2.0	6.0
17	82.0	1.0	12.0	0.0
18	55.0	8.0	22.0	10.0
19	27.0	38.0	3.0	27.0
20	24.0	54.0	5.0	12.0
21	14.0	41.0	13.0	27.0
22	48.0	24.0	12.0	11.0
23	24.0	41.0	6.0	24.0
24	48.0	7.0	17.0	23.0
25	34.0	13.0	38.0	10.0

PFM

	A	C	G	T
01	0.674	0.137	0.137	0.053
02	0.695	0.042	0.232	0.032
03	0.211	0.063	0.084	0.642
04	0.326	0.232	0.158	0.284
05	0.579	0.042	0.053	0.326
06	0.084	0.042	0.747	0.126
07	0.853	0.063	0.084	0.0
08	0.095	0.063	0.053	0.789
09	0.684	0.032	0.084	0.2
10	0.411	0.368	0.074	0.147
11	0.905	0.021	0.063	0.011
12	0.168	0.126	0.095	0.611
13	0.589	0.0	0.347	0.063
14	0.084	0.0	0.905	0.011
15	0.116	0.011	0.874	0.0
16	0.684	0.232	0.021	0.063
17	0.863	0.011	0.126	0.0
18	0.579	0.084	0.232	0.105
19	0.284	0.4	0.032	0.284
20	0.253	0.568	0.053	0.126
21	0.147	0.432	0.137	0.284
22	0.505	0.253	0.126	0.116
23	0.253	0.432	0.063	0.253
24	0.505	0.074	0.179	0.242
25	0.358	0.137	0.4	0.105

PWM

	A	C	G	T
01	0.962	-0.566	-0.566	-1.4
02	0.992	-1.578	-0.073	-1.794
03	-0.163	-1.249	-1.002	0.915
04	0.256	-0.073	-0.433	0.123
05	0.813	-1.578	-1.4	0.256
06	-1.002	-1.578	1.064	-0.639
07	1.194	-1.249	-1.002	-3.085
08	-0.898	-1.249	-1.4	1.118
09	0.977	-1.794	-1.002	-0.212
10	0.478	0.373	-1.118	-0.497
11	1.253	-2.071	-1.249	-2.454
12	-0.373	-0.639	-0.898	0.865
13	0.831	-3.085	0.316	-1.249
14	-1.002	-3.085	1.253	-2.454
15	-0.718	-2.454	1.218	-3.085
16	0.977	-0.073	-2.071	-1.249
17	1.206	-2.454	-0.639	-3.085
18	0.813	-1.002	-0.073	-0.804
19	0.123	0.453	-1.794	0.123
20	0.01	0.795	-1.4	-0.639
21	-0.497	0.527	-0.566	0.123
22	0.68	0.01	-0.639	-0.718
23	0.01	0.527	-1.249	0.01
24	0.68	-1.118	-0.316	-0.031
25	0.345	-0.566	0.453	-0.804

Standard thresholds

P-value	Threshold
0.001	3.44461
0.0005	4.45911
0.0001	6.61051