ZN142.H14INVIVO.0.PSGI.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ZN142.H14INVIVO.0.PSGI.A
Gene (human)	ZNF142 (GeneCards)
Gene synonyms (human)	KIAA0236
Gene (mouse)	Znf142
Gene synonyms (mouse)	Kiaa0236, Zfp142
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	A

Motif length	12
Consensus	SCGGGCGGGCSS
GC content	92.5%
Information content (bits; total / per base)	15.857 / 1.321
Data sources	ChIP-Seq + HT-SELEX + Genomic HT-SELEX + SMiLe-Seq
Aligned words	987
Previous names

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	Centrality, median	Centrality, best
Overall	2 (4)	0.886	0.892	0.807	0.813	0.667	0.689	84.611	93.013

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
GFPIVT, 2 experiments	median	0.819	0.817	0.762	0.764	0.683	0.694
GFPIVT, 2 experiments	best	0.987	0.977	0.964	0.949	0.846	0.847

Genomic HT-SELEX benchmarking		Centrality	pseudo-auROC	auROC	auPR
GFPIVT, 1 experiments	median	173.094	0.894	0.911	0.833
GFPIVT, 1 experiments	best	173.585	0.902	0.913	0.835

SMiLE-Seq benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 1 experiments	median	0.882	0.841	0.749	0.73	0.633	0.644
Overall, 1 experiments	best	0.882	0.841	0.749	0.73	0.633	0.644

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	Multiple dispersed zinc fingers {2.3.4} (TFClass)
TF subfamily	Unclassified {2.3.4.0} (TFClass)
TFClass ID	TFClass: 2.3.4.0.37
HGNC	HGNC:12927
MGI	MGI:1924514
EntrezGene (human)	GeneID:7701 (SSTAR profile)
EntrezGene (mouse)	GeneID:77264 (SSTAR profile)
UniProt ID (human)	ZN142_HUMAN
UniProt ID (mouse)	ZN142_MOUSE
UniProt AC (human)	P52746 (TFClass)
UniProt AC (mouse)	G5E869 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	2 human, 0 mouse
HT-SELEX	2 overall: 0 Lysate, 0 IVT, 2 GFPIVT
Genomic HT-SELEX	1 overall: 0 Lysate, 0 IVT, 1 GFPIVT
SMiLE-Seq	1
PBM	0

PCM	ZN142.H14INVIVO.0.PSGI.A.pcm
PWM	ZN142.H14INVIVO.0.PSGI.A.pwm
PFM	ZN142.H14INVIVO.0.PSGI.A.pfm
Threshold to P-value map	ZN142.H14INVIVO.0.PSGI.A.thr
Motif in other formats
JASPAR format	ZN142.H14INVIVO.0.PSGI.A_jaspar_format.txt
MEME format	ZN142.H14INVIVO.0.PSGI.A_meme_format.meme
Transfac format	ZN142.H14INVIVO.0.PSGI.A_transfac_format.txt
Homer format	ZN142.H14INVIVO.0.PSGI.A_homer_format_0.001.txt ZN142.H14INVIVO.0.PSGI.A_homer_format_0.0005.txt ZN142.H14INVIVO.0.PSGI.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	33.0	124.0	750.0	80.0
02	25.0	912.0	15.0	35.0
03	16.0	9.0	947.0	15.0
04	12.0	136.0	819.0	20.0
05	20.0	40.0	861.0	66.0
06	128.0	851.0	3.0	5.0
07	11.0	3.0	968.0	5.0
08	0.0	10.0	972.0	5.0
09	3.0	21.0	956.0	7.0
10	90.0	850.0	4.0	43.0
11	93.0	109.0	693.0	92.0
12	42.0	488.0	415.0	42.0

PFM

	A	C	G	T
01	0.033	0.126	0.76	0.081
02	0.025	0.924	0.015	0.035
03	0.016	0.009	0.959	0.015
04	0.012	0.138	0.83	0.02
05	0.02	0.041	0.872	0.067
06	0.13	0.862	0.003	0.005
07	0.011	0.003	0.981	0.005
08	0.0	0.01	0.985	0.005
09	0.003	0.021	0.969	0.007
10	0.091	0.861	0.004	0.044
11	0.094	0.11	0.702	0.093
12	0.043	0.494	0.42	0.043

PWM

	A	C	G	T
01	-1.968	-0.681	1.107	-1.112
02	-2.23	1.302	-2.699	-1.912
03	-2.64	-3.143	1.34	-2.699
04	-2.896	-0.59	1.195	-2.437
05	-2.437	-1.784	1.245	-1.3
06	-0.65	1.233	-3.963	-3.61
07	-2.972	-3.963	1.362	-3.61
08	-4.971	-3.054	1.366	-3.61
09	-3.963	-2.392	1.349	-3.349
10	-0.997	1.232	-3.771	-1.715
11	-0.964	-0.808	1.028	-0.975
12	-1.737	0.679	0.517	-1.737

Standard thresholds

P-value	Threshold
0.001	2.50262
0.0005	3.72585
0.0001	6.2863