ZN140.H14INVITRO.1.SM.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ZN140.H14INVITRO.1.SM.B
Gene (human)	ZNF140 (GeneCards)
Gene synonyms (human)
Gene (mouse)
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	B

Motif length	15
Consensus	nhRCAATTCCGCKCn
GC content	53.61%
Information content (bits; total / per base)	18.017 / 1.201
Data sources	HT-SELEX + Methyl-HT-SELEX
Aligned words	348
Previous names	ZN140.H12INVITRO.1.SM.B

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	2 (11)	0.679	0.871	0.663	0.868	0.709	0.905	4.117	6.437	140.456	402.602

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 2 experiments	median	0.739	0.759	0.605	0.632	0.551	0.575
Overall, 2 experiments	best	0.789	0.81	0.622	0.657	0.555	0.588
Methyl HT-SELEX, 1 experiments	median	0.789	0.81	0.622	0.657	0.555	0.588
Methyl HT-SELEX, 1 experiments	best	0.789	0.81	0.622	0.657	0.555	0.588
Non-Methyl HT-SELEX, 1 experiments	median	0.689	0.708	0.588	0.607	0.547	0.563
Non-Methyl HT-SELEX, 1 experiments	best	0.689	0.708	0.588	0.607	0.547	0.563

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	More than 3 adjacent zinc fingers {2.3.3} (TFClass)
TF subfamily	ZNF302-like {2.3.3.44} (TFClass)
TFClass ID	TFClass: 2.3.3.44.4
HGNC	HGNC:12925
MGI
EntrezGene (human)	GeneID:7699 (SSTAR profile)
EntrezGene (mouse)
UniProt ID (human)	ZN140_HUMAN
UniProt ID (mouse)
UniProt AC (human)	P52738 (TFClass)
UniProt AC (mouse)
GRECO-DB-TF	yes

ChIP-Seq	2 human, 0 mouse
HT-SELEX	1
Methyl-HT-SELEX	1
Genomic HT-SELEX	0 overall: 0 Lysate, 0 IVT, 0 GFPIVT
SMiLE-Seq	0
PBM	0

PCM	ZN140.H14INVITRO.1.SM.B.pcm
PWM	ZN140.H14INVITRO.1.SM.B.pwm
PFM	ZN140.H14INVITRO.1.SM.B.pfm
Threshold to P-value map	ZN140.H14INVITRO.1.SM.B.thr
Motif in other formats
JASPAR format	ZN140.H14INVITRO.1.SM.B_jaspar_format.txt
MEME format	ZN140.H14INVITRO.1.SM.B_meme_format.meme
Transfac format	ZN140.H14INVITRO.1.SM.B_transfac_format.txt
Homer format	ZN140.H14INVITRO.1.SM.B_homer_format_0.001.txt ZN140.H14INVITRO.1.SM.B_homer_format_0.0005.txt ZN140.H14INVITRO.1.SM.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	68.5	98.5	75.5	105.5
02	136.75	62.75	46.75	101.75
03	107.0	27.0	206.0	8.0
04	4.0	328.0	9.0	7.0
05	301.0	28.0	1.0	18.0
06	323.0	13.0	8.0	4.0
07	0.0	0.0	0.0	348.0
08	0.0	0.0	0.0	348.0
09	1.0	346.0	0.0	1.0
10	0.0	346.0	0.0	2.0
11	7.0	15.0	322.0	4.0
12	11.0	317.0	0.0	20.0
13	7.0	24.0	47.0	270.0
14	22.0	281.0	18.0	27.0
15	102.5	107.5	71.5	66.5

PFM

	A	C	G	T
01	0.197	0.283	0.217	0.303
02	0.393	0.18	0.134	0.292
03	0.307	0.078	0.592	0.023
04	0.011	0.943	0.026	0.02
05	0.865	0.08	0.003	0.052
06	0.928	0.037	0.023	0.011
07	0.0	0.0	0.0	1.0
08	0.0	0.0	0.0	1.0
09	0.003	0.994	0.0	0.003
10	0.0	0.994	0.0	0.006
11	0.02	0.043	0.925	0.011
12	0.032	0.911	0.0	0.057
13	0.02	0.069	0.135	0.776
14	0.063	0.807	0.052	0.078
15	0.295	0.309	0.205	0.191

PWM

	A	C	G	T
01	-0.235	0.122	-0.139	0.19
02	0.446	-0.32	-0.607	0.154
03	0.204	-1.134	0.852	-2.235
04	-2.785	1.315	-2.135	-2.347
05	1.229	-1.099	-3.581	-1.514
06	1.3	-1.811	-2.235	-2.785
07	-4.102	-4.102	-4.102	1.374
08	-4.102	-4.102	-4.102	1.374
09	-3.581	1.368	-4.102	-3.581
10	-4.102	1.368	-4.102	-3.24
11	-2.347	-1.681	1.296	-2.785
12	-1.96	1.281	-4.102	-1.416
13	-2.347	-1.245	-0.602	1.121
14	-1.327	1.161	-1.514	-1.134
15	0.161	0.208	-0.193	-0.264

Standard thresholds

P-value	Threshold
0.001	1.46711
0.0005	2.83391
0.0001	5.67346