ZN131.H14INVIVO.0.PSGI.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ZN131.H14INVIVO.0.PSGI.A
Gene (human)	ZNF131 (GeneCards)
Gene synonyms (human)
Gene (mouse)	Znf131
Gene synonyms (mouse)	Zfp131
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	A

Motif length	8
Consensus	ShGCGMCd
GC content	80.5%
Information content (bits; total / per base)	9.798 / 1.225
Data sources	ChIP-Seq + HT-SELEX + Genomic HT-SELEX + SMiLe-Seq
Aligned words	997
Previous names

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	Centrality, median	Centrality, best
Overall	2 (2)	0.842	0.847	0.688	0.699	0.542	0.555	37.914	38.208

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
overall, 4 experiments	median	0.973	0.96	0.929	0.909	0.839	0.831
overall, 4 experiments	best	0.991	0.982	0.982	0.972	0.954	0.939
Lysate, 1 experiments	median	0.991	0.982	0.982	0.972	0.954	0.939
Lysate, 1 experiments	best	0.991	0.982	0.982	0.972	0.954	0.939
IVT, 1 experiments	median	0.617	0.606	0.565	0.561	0.537	0.538
IVT, 1 experiments	best	0.617	0.606	0.565	0.561	0.537	0.538
GFPIVT, 2 experiments	median	0.973	0.96	0.929	0.909	0.839	0.831
GFPIVT, 2 experiments	best	0.979	0.968	0.963	0.944	0.933	0.908

Genomic HT-SELEX benchmarking		Centrality	pseudo-auROC	auROC	auPR
overall, 3 experiments	median	110.824	0.611	0.801	0.644
overall, 3 experiments	best	193.745	0.673	0.83	0.672
Lysate, 1 experiments	median	110.824	0.649	0.828	0.662
Lysate, 1 experiments	best	193.745	0.673	0.83	0.672
GFPIVT, 2 experiments	median	78.882	0.596	0.741	0.608
GFPIVT, 2 experiments	best	180.409	0.611	0.801	0.653

SMiLE-Seq benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 3 experiments	median	0.899	0.851	0.857	0.803	0.754	0.729
Overall, 3 experiments	best	0.914	0.858	0.884	0.828	0.828	0.781

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	More than 3 adjacent zinc fingers {2.3.3} (TFClass)
TF subfamily	Unclassified {2.3.3.0} (TFClass)
TFClass ID	TFClass: 2.3.3.0.34
HGNC	HGNC:12915
MGI	MGI:1919715
EntrezGene (human)	GeneID:7690 (SSTAR profile)
EntrezGene (mouse)	GeneID:72465 (SSTAR profile)
UniProt ID (human)	ZN131_HUMAN
UniProt ID (mouse)	ZN131_MOUSE
UniProt AC (human)	P52739 (TFClass)
UniProt AC (mouse)	Q8K3J5 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	2 human, 0 mouse
HT-SELEX	4 overall: 1 Lysate, 1 IVT, 2 GFPIVT
Genomic HT-SELEX	3 overall: 1 Lysate, 0 IVT, 2 GFPIVT
SMiLE-Seq	3
PBM	0

PCM	ZN131.H14INVIVO.0.PSGI.A.pcm
PWM	ZN131.H14INVIVO.0.PSGI.A.pwm
PFM	ZN131.H14INVIVO.0.PSGI.A.pfm
Threshold to P-value map	ZN131.H14INVIVO.0.PSGI.A.thr
Motif in other formats
JASPAR format	ZN131.H14INVIVO.0.PSGI.A_jaspar_format.txt
MEME format	ZN131.H14INVIVO.0.PSGI.A_meme_format.meme
Transfac format	ZN131.H14INVIVO.0.PSGI.A_transfac_format.txt
Homer format	ZN131.H14INVIVO.0.PSGI.A_homer_format_0.001.txt ZN131.H14INVIVO.0.PSGI.A_homer_format_0.0005.txt ZN131.H14INVIVO.0.PSGI.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	83.0	383.0	527.0	4.0
02	112.0	414.0	102.0	369.0
03	1.0	2.0	994.0	0.0
04	1.0	984.0	1.0	11.0
05	6.0	1.0	988.0	2.0
06	498.0	488.0	3.0	8.0
07	3.0	993.0	0.0	1.0
08	294.0	80.0	461.0	162.0

PFM

	A	C	G	T
01	0.083	0.384	0.529	0.004
02	0.112	0.415	0.102	0.37
03	0.001	0.002	0.997	0.0
04	0.001	0.987	0.001	0.011
05	0.006	0.001	0.991	0.002
06	0.499	0.489	0.003	0.008
07	0.003	0.996	0.0	0.001
08	0.295	0.08	0.462	0.162

PWM

	A	C	G	T
01	-1.086	0.427	0.745	-3.78
02	-0.792	0.505	-0.884	0.39
03	-4.522	-4.21	1.378	-4.979
04	-4.522	1.368	-4.522	-2.982
05	-3.481	-4.522	1.372	-4.21
06	0.689	0.668	-3.972	-3.251
07	-3.972	1.377	-4.979	-4.522
08	0.164	-1.122	0.612	-0.427

Standard thresholds

P-value	Threshold
0.001	5.114425
0.0005	6.308165
0.0001	7.61147