ZIC5.H14INVIVO.0.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ZIC5.H14INVIVO.0.P.B
Gene (human)	ZIC5 (GeneCards)
Gene synonyms (human)
Gene (mouse)	Zic5
Gene synonyms (mouse)	Opr
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	15
Consensus	dCnCMGCRGGRGGYS
GC content	75.67%
Information content (bits; total / per base)	16.144 / 1.076
Data sources	ChIP-Seq
Aligned words	1000
Previous names	ZIC5.H12INVIVO.0.P.B

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	9 (61)	0.946	0.98	0.908	0.965	0.911	0.965	3.884	5.297	410.469	529.495

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 2 experiments	median	0.96	0.963	0.768	0.803	0.609	0.669
Overall, 2 experiments	best	1.0	1.0	0.862	0.884	0.654	0.718
Methyl HT-SELEX, 1 experiments	median	1.0	1.0	0.862	0.884	0.654	0.718
Methyl HT-SELEX, 1 experiments	best	1.0	1.0	0.862	0.884	0.654	0.718
Non-Methyl HT-SELEX, 1 experiments	median	0.92	0.926	0.675	0.722	0.565	0.619
Non-Methyl HT-SELEX, 1 experiments	best	0.92	0.926	0.675	0.722	0.565	0.619

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	More than 3 adjacent zinc fingers {2.3.3} (TFClass)
TF subfamily	GLI-like {2.3.3.1} (TFClass)
TFClass ID	TFClass: 2.3.3.1.11
HGNC	HGNC:20322
MGI	MGI:1929518
EntrezGene (human)	GeneID:85416 (SSTAR profile)
EntrezGene (mouse)	GeneID:65100 (SSTAR profile)
UniProt ID (human)	ZIC5_HUMAN
UniProt ID (mouse)	ZIC5_MOUSE
UniProt AC (human)	Q96T25 (TFClass)
UniProt AC (mouse)	Q7TQ40 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	9 human, 0 mouse
HT-SELEX	1
Methyl-HT-SELEX	1
Genomic HT-SELEX	0 overall: 0 Lysate, 0 IVT, 0 GFPIVT
SMiLE-Seq	0
PBM	0

PCM	ZIC5.H14INVIVO.0.P.B.pcm
PWM	ZIC5.H14INVIVO.0.P.B.pwm
PFM	ZIC5.H14INVIVO.0.P.B.pfm
Threshold to P-value map	ZIC5.H14INVIVO.0.P.B.thr
Motif in other formats
JASPAR format	ZIC5.H14INVIVO.0.P.B_jaspar_format.txt
MEME format	ZIC5.H14INVIVO.0.P.B_meme_format.meme
Transfac format	ZIC5.H14INVIVO.0.P.B_transfac_format.txt
Homer format	ZIC5.H14INVIVO.0.P.B_homer_format_0.001.txt ZIC5.H14INVIVO.0.P.B_homer_format_0.0005.txt ZIC5.H14INVIVO.0.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	216.0	103.0	457.0	224.0
02	103.0	826.0	70.0	1.0
03	385.0	193.0	241.0	181.0
04	2.0	987.0	3.0	8.0
05	691.0	187.0	76.0	46.0
06	49.0	54.0	895.0	2.0
07	3.0	946.0	1.0	50.0
08	613.0	1.0	376.0	10.0
09	3.0	1.0	978.0	18.0
10	1.0	3.0	995.0	1.0
11	194.0	23.0	696.0	87.0
12	60.0	32.0	863.0	45.0
13	36.0	28.0	878.0	58.0
14	4.0	462.0	135.0	399.0
15	117.0	645.0	196.0	42.0

PFM

	A	C	G	T
01	0.216	0.103	0.457	0.224
02	0.103	0.826	0.07	0.001
03	0.385	0.193	0.241	0.181
04	0.002	0.987	0.003	0.008
05	0.691	0.187	0.076	0.046
06	0.049	0.054	0.895	0.002
07	0.003	0.946	0.001	0.05
08	0.613	0.001	0.376	0.01
09	0.003	0.001	0.978	0.018
10	0.001	0.003	0.995	0.001
11	0.194	0.023	0.696	0.087
12	0.06	0.032	0.863	0.045
13	0.036	0.028	0.878	0.058
14	0.004	0.462	0.135	0.399
15	0.117	0.645	0.196	0.042

PWM

	A	C	G	T
01	-0.145	-0.877	0.6	-0.109
02	-0.877	1.19	-1.255	-4.525
03	0.429	-0.257	-0.036	-0.32
04	-4.213	1.368	-3.975	-3.253
05	1.012	-0.288	-1.175	-1.663
06	-1.602	-1.508	1.27	-4.213
07	-3.975	1.326	-4.525	-1.582
08	0.893	-4.525	0.406	-3.066
09	-3.975	-4.525	1.359	-2.546
10	-4.525	-3.975	1.376	-4.525
11	-0.252	-2.32	1.019	-1.043
12	-1.406	-2.01	1.234	-1.684
13	-1.898	-2.136	1.251	-1.439
14	-3.783	0.611	-0.61	0.465
15	-0.752	0.944	-0.241	-1.75

Standard thresholds

P-value	Threshold
0.001	2.24106
0.0005	3.53206
0.0001	6.21636