ZFTA.H14INVIVO.0.PSGIB.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ZFTA.H14INVIVO.0.PSGIB.A
Gene (human)	ZFTA (GeneCards)
Gene synonyms (human)
Gene (mouse)	Zfta
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	A

Motif length	11
Consensus	hGTGGCCCCbv
GC content	76.4%
Information content (bits; total / per base)	14.337 / 1.303
Data sources	ChIP-Seq + HT-SELEX + Genomic HT-SELEX + SMiLe-Seq + PBM
Aligned words	500
Previous names

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	Centrality, median	Centrality, best
Overall	2 (2)	0.976	0.978	0.938	0.941	0.906	0.937	292.321	356.721

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
GFPIVT, 1 experiments	median	0.998	0.997	0.946	0.949	0.718	0.772
GFPIVT, 1 experiments	best	0.998	0.997	0.946	0.949	0.718	0.772

Genomic HT-SELEX benchmarking		Centrality	pseudo-auROC	auROC	auPR
overall, 3 experiments	median	293.745	0.919	0.948	0.911
overall, 3 experiments	best	647.284	0.945	0.978	0.941
Lysate, 2 experiments	median	251.202	0.81	0.858	0.855
Lysate, 2 experiments	best	375.745	0.876	0.911	0.896
GFPIVT, 1 experiments	median	411.041	0.939	0.962	0.928
GFPIVT, 1 experiments	best	647.284	0.945	0.978	0.941

SMiLE-Seq benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 1 experiments	median	0.995	0.993	0.989	0.984	0.872	0.883
Overall, 1 experiments	best	0.995	0.993	0.989	0.984	0.872	0.883

PBM benchmarking		auROC, QNZS	auPR, QNZS	auROC, SD	auPR, SD
Overall, 4 experiments	median	0.863	0.502	0.899	0.496
Overall, 4 experiments	best	0.91	0.506	0.971	0.574

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	BED zinc finger {2.3.5} (TFClass)
TF subfamily	{2.3.5.0} (TFClass)
TFClass ID	TFClass: 2.3.5.0.257
HGNC
MGI
EntrezGene (human)
EntrezGene (mouse)
UniProt ID (human)	ZFTA_HUMAN
UniProt ID (mouse)	ZFTA_MOUSE
UniProt AC (human)	C9JLR9 (TFClass)
UniProt AC (mouse)	Q4VA45 (TFClass)
GRECO-DB-TF	no

ChIP-Seq	2 human, 0 mouse
HT-SELEX	1 overall: 0 Lysate, 0 IVT, 1 GFPIVT
Genomic HT-SELEX	3 overall: 2 Lysate, 0 IVT, 1 GFPIVT
SMiLE-Seq	1
PBM	4

PCM	ZFTA.H14INVIVO.0.PSGIB.A.pcm
PWM	ZFTA.H14INVIVO.0.PSGIB.A.pwm
PFM	ZFTA.H14INVIVO.0.PSGIB.A.pfm
Threshold to P-value map	ZFTA.H14INVIVO.0.PSGIB.A.thr
Motif in other formats
JASPAR format	ZFTA.H14INVIVO.0.PSGIB.A_jaspar_format.txt
MEME format	ZFTA.H14INVIVO.0.PSGIB.A_meme_format.meme
Transfac format	ZFTA.H14INVIVO.0.PSGIB.A_transfac_format.txt
Homer format	ZFTA.H14INVIVO.0.PSGIB.A_homer_format_0.001.txt ZFTA.H14INVIVO.0.PSGIB.A_homer_format_0.0005.txt ZFTA.H14INVIVO.0.PSGIB.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	80.0	134.0	50.0	236.0
02	0.0	7.0	462.0	31.0
03	1.0	0.0	99.0	400.0
04	1.0	0.0	499.0	0.0
05	0.0	0.0	500.0	0.0
06	0.0	498.0	0.0	2.0
07	0.0	500.0	0.0	0.0
08	0.0	500.0	0.0	0.0
09	2.0	360.0	9.0	129.0
10	77.0	151.0	90.0	182.0
11	113.0	97.0	246.0	44.0

PFM

	A	C	G	T
01	0.16	0.268	0.1	0.472
02	0.0	0.014	0.924	0.062
03	0.002	0.0	0.198	0.8
04	0.002	0.0	0.998	0.0
05	0.0	0.0	1.0	0.0
06	0.0	0.996	0.0	0.004
07	0.0	1.0	0.0	0.0
08	0.0	1.0	0.0	0.0
09	0.004	0.72	0.018	0.258
10	0.154	0.302	0.18	0.364
11	0.226	0.194	0.492	0.088

PWM

	A	C	G	T
01	-0.439	0.069	-0.898	0.63
02	-4.4	-2.694	1.298	-1.358
03	-3.903	-4.4	-0.23	1.155
04	-3.903	-4.4	1.375	-4.4
05	-4.4	-4.4	1.377	-4.4
06	-4.4	1.373	-4.4	-3.573
07	-4.4	1.377	-4.4	-4.4
08	-4.4	1.377	-4.4	-4.4
09	-3.573	1.05	-2.484	0.031
10	-0.477	0.187	-0.324	0.372
11	-0.1	-0.25	0.671	-1.022

Standard thresholds

P-value	Threshold
0.001	2.68227
0.0005	3.986395
0.0001	6.496725