ZBT8A.H14INVIVO.0.PSGI.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ZBT8A.H14INVIVO.0.PSGI.A
Gene (human)	ZBTB8A (GeneCards)
Gene synonyms (human)
Gene (mouse)	Zbtb8a
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	A

Motif length	8
Consensus	RCGCCCKb
GC content	85.28%
Information content (bits; total / per base)	10.671 / 1.334
Data sources	ChIP-Seq + HT-SELEX + Genomic HT-SELEX + SMiLe-Seq
Aligned words	997
Previous names

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	Centrality, median	Centrality, best
Overall	3 (3)	0.83	0.84	0.693	0.696	0.603	0.616	55.745	77.046

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
overall, 3 experiments	median	0.87	0.791	0.832	0.766	0.685	0.678
overall, 3 experiments	best	0.93	0.881	0.944	0.895	0.934	0.887
Lysate, 2 experiments	median	0.9	0.836	0.888	0.831	0.81	0.783
Lysate, 2 experiments	best	0.93	0.881	0.944	0.895	0.934	0.887
IVT, 1 experiments	median	0.783	0.705	0.729	0.67	0.642	0.619
IVT, 1 experiments	best	0.783	0.705	0.729	0.67	0.642	0.619

Genomic HT-SELEX benchmarking		Centrality	pseudo-auROC	auROC	auPR
Lysate, 2 experiments	median	14.117	0.568	0.709	0.593
Lysate, 2 experiments	best	165.092	0.661	0.784	0.617

SMiLE-Seq benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 1 experiments	median	0.549	0.534	0.54	0.526	0.53	0.52
Overall, 1 experiments	best	0.549	0.534	0.54	0.526	0.53	0.52

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	Other with up to three adjacent zinc fingers {2.3.2} (TFClass)
TF subfamily	BTB-POZ {2.3.2.1} (TFClass)
TFClass ID	TFClass: 2.3.2.1.255
HGNC
MGI
EntrezGene (human)
EntrezGene (mouse)
UniProt ID (human)	ZBT8A_HUMAN
UniProt ID (mouse)	ZBT8A_MOUSE
UniProt AC (human)	Q96BR9 (TFClass)
UniProt AC (mouse)	Q9CWH1 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	3 human, 0 mouse
HT-SELEX	3 overall: 2 Lysate, 1 IVT, 0 GFPIVT
Genomic HT-SELEX	2 overall: 2 Lysate, 0 IVT, 0 GFPIVT
SMiLE-Seq	1
PBM	0

PCM	ZBT8A.H14INVIVO.0.PSGI.A.pcm
PWM	ZBT8A.H14INVIVO.0.PSGI.A.pwm
PFM	ZBT8A.H14INVIVO.0.PSGI.A.pfm
Threshold to P-value map	ZBT8A.H14INVIVO.0.PSGI.A.thr
Motif in other formats
JASPAR format	ZBT8A.H14INVIVO.0.PSGI.A_jaspar_format.txt
MEME format	ZBT8A.H14INVIVO.0.PSGI.A_meme_format.meme
Transfac format	ZBT8A.H14INVIVO.0.PSGI.A_transfac_format.txt
Homer format	ZBT8A.H14INVIVO.0.PSGI.A_homer_format_0.001.txt ZBT8A.H14INVIVO.0.PSGI.A_homer_format_0.0005.txt ZBT8A.H14INVIVO.0.PSGI.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	149.0	107.0	711.0	30.0
02	133.0	849.0	0.0	15.0
03	1.0	1.0	993.0	2.0
04	3.0	994.0	0.0	0.0
05	0.0	997.0	0.0	0.0
06	1.0	987.0	0.0	9.0
07	238.0	2.0	357.0	400.0
08	72.0	496.0	308.0	121.0

PFM

	A	C	G	T
01	0.149	0.107	0.713	0.03
02	0.133	0.852	0.0	0.015
03	0.001	0.001	0.996	0.002
04	0.003	0.997	0.0	0.0
05	0.0	1.0	0.0	0.0
06	0.001	0.99	0.0	0.009
07	0.239	0.002	0.358	0.401
08	0.072	0.497	0.309	0.121

PWM

	A	C	G	T
01	-0.51	-0.837	1.044	-2.068
02	-0.622	1.221	-4.979	-2.708
03	-4.522	-4.522	1.377	-4.21
04	-3.972	1.378	-4.979	-4.979
05	-4.979	1.381	-4.979	-4.979
06	-4.522	1.371	-4.979	-3.153
07	-0.046	-4.21	0.357	0.47
08	-1.225	0.685	0.21	-0.715

Standard thresholds

P-value	Threshold
0.001	4.58264
0.0005	5.766815
0.0001	7.496935