| Motif | ZBT8A.H14INVITRO.0.PSGI.A |
| Gene (human) | ZBTB8A (GeneCards) |
| Gene synonyms (human) | |
| Gene (mouse) | Zbtb8a |
| Gene synonyms (mouse) | |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 0 |
| Quality | A |
| Motif | ZBT8A.H14INVITRO.0.PSGI.A |
| Gene (human) | ZBTB8A (GeneCards) |
| Gene synonyms (human) | |
| Gene (mouse) | Zbtb8a |
| Gene synonyms (mouse) | |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 0 |
| Quality | A |
| Motif length | 21 |
| Consensus | nhKACGCCCWWWWdnSSSbnn |
| GC content | 54.05% |
| Information content (bits; total / per base) | 17.571 / 0.837 |
| Data sources | ChIP-Seq + HT-SELEX + Genomic HT-SELEX + SMiLe-Seq |
| Aligned words | 1798 |
| Previous names |
| ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | Centrality, median | Centrality, best |
|---|---|---|---|---|---|---|---|---|---|
| Overall | 3 (3) | 0.785 | 0.794 | 0.58 | 0.611 | 0.497 | 0.508 | 24.678 | 31.585 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| overall, 3 experiments | median | 0.999 | 0.998 | 0.925 | 0.927 | 0.74 | 0.773 |
| best | 1.0 | 1.0 | 1.0 | 0.999 | 0.996 | 0.995 | |
| Lysate, 2 experiments | median | 1.0 | 0.999 | 0.963 | 0.963 | 0.868 | 0.884 |
| best | 1.0 | 1.0 | 1.0 | 0.999 | 0.996 | 0.995 | |
| IVT, 1 experiments | median | 0.948 | 0.936 | 0.819 | 0.811 | 0.68 | 0.697 |
| best | 0.948 | 0.936 | 0.819 | 0.811 | 0.68 | 0.697 | |
| Genomic HT-SELEX benchmarking | Centrality | pseudo-auROC | auROC | auPR | |
|---|---|---|---|---|---|
| Lysate, 2 experiments | median | 8.045 | 0.611 | 0.744 | 0.644 |
| best | 74.77 | 0.691 | 0.848 | 0.732 | |
| SMiLE-Seq benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Overall, 1 experiments | median | 0.568 | 0.545 | 0.549 | 0.533 | 0.533 | 0.524 |
| best | 0.568 | 0.545 | 0.549 | 0.533 | 0.533 | 0.524 | |
| TF superclass | Zinc-coordinating DNA-binding domains {2} (TFClass) |
| TF class | C2H2 zinc finger factors {2.3} (TFClass) |
| TF family | Other with up to three adjacent zinc fingers {2.3.2} (TFClass) |
| TF subfamily | BTB-POZ {2.3.2.1} (TFClass) |
| TFClass ID | TFClass: 2.3.2.1.255 |
| HGNC | |
| MGI | |
| EntrezGene (human) | |
| EntrezGene (mouse) | |
| UniProt ID (human) | ZBT8A_HUMAN |
| UniProt ID (mouse) | ZBT8A_MOUSE |
| UniProt AC (human) | Q96BR9 (TFClass) |
| UniProt AC (mouse) | Q9CWH1 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 3 human, 0 mouse |
| HT-SELEX | 3 overall: 2 Lysate, 1 IVT, 0 GFPIVT |
| Genomic HT-SELEX | 2 overall: 2 Lysate, 0 IVT, 0 GFPIVT |
| SMiLE-Seq | 1 |
| PBM | 0 |
| PCM | ZBT8A.H14INVITRO.0.PSGI.A.pcm |
| PWM | ZBT8A.H14INVITRO.0.PSGI.A.pwm |
| PFM | ZBT8A.H14INVITRO.0.PSGI.A.pfm |
| Threshold to P-value map | ZBT8A.H14INVITRO.0.PSGI.A.thr |
| Motif in other formats | |
| JASPAR format | ZBT8A.H14INVITRO.0.PSGI.A_jaspar_format.txt |
| MEME format | ZBT8A.H14INVITRO.0.PSGI.A_meme_format.meme |
| Transfac format | ZBT8A.H14INVITRO.0.PSGI.A_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 455.25 | 354.25 | 429.25 | 559.25 |
| 02 | 287.0 | 314.0 | 199.0 | 998.0 |
| 03 | 279.0 | 87.0 | 364.0 | 1068.0 |
| 04 | 1687.0 | 5.0 | 94.0 | 12.0 |
| 05 | 6.0 | 1785.0 | 0.0 | 7.0 |
| 06 | 0.0 | 0.0 | 1798.0 | 0.0 |
| 07 | 0.0 | 1798.0 | 0.0 | 0.0 |
| 08 | 0.0 | 1798.0 | 0.0 | 0.0 |
| 09 | 0.0 | 1784.0 | 0.0 | 14.0 |
| 10 | 307.0 | 65.0 | 46.0 | 1380.0 |
| 11 | 999.0 | 75.0 | 48.0 | 676.0 |
| 12 | 865.0 | 117.0 | 24.0 | 792.0 |
| 13 | 487.0 | 49.0 | 100.0 | 1162.0 |
| 14 | 605.0 | 176.0 | 186.0 | 831.0 |
| 15 | 648.0 | 270.0 | 492.0 | 388.0 |
| 16 | 219.0 | 277.0 | 1114.0 | 188.0 |
| 17 | 149.0 | 361.0 | 1146.0 | 142.0 |
| 18 | 102.0 | 821.0 | 778.0 | 97.0 |
| 19 | 165.0 | 1004.0 | 436.0 | 193.0 |
| 20 | 247.75 | 611.75 | 528.75 | 409.75 |
| 21 | 371.25 | 553.25 | 319.25 | 554.25 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.253 | 0.197 | 0.239 | 0.311 |
| 02 | 0.16 | 0.175 | 0.111 | 0.555 |
| 03 | 0.155 | 0.048 | 0.202 | 0.594 |
| 04 | 0.938 | 0.003 | 0.052 | 0.007 |
| 05 | 0.003 | 0.993 | 0.0 | 0.004 |
| 06 | 0.0 | 0.0 | 1.0 | 0.0 |
| 07 | 0.0 | 1.0 | 0.0 | 0.0 |
| 08 | 0.0 | 1.0 | 0.0 | 0.0 |
| 09 | 0.0 | 0.992 | 0.0 | 0.008 |
| 10 | 0.171 | 0.036 | 0.026 | 0.768 |
| 11 | 0.556 | 0.042 | 0.027 | 0.376 |
| 12 | 0.481 | 0.065 | 0.013 | 0.44 |
| 13 | 0.271 | 0.027 | 0.056 | 0.646 |
| 14 | 0.336 | 0.098 | 0.103 | 0.462 |
| 15 | 0.36 | 0.15 | 0.274 | 0.216 |
| 16 | 0.122 | 0.154 | 0.62 | 0.105 |
| 17 | 0.083 | 0.201 | 0.637 | 0.079 |
| 18 | 0.057 | 0.457 | 0.433 | 0.054 |
| 19 | 0.092 | 0.558 | 0.242 | 0.107 |
| 20 | 0.138 | 0.34 | 0.294 | 0.228 |
| 21 | 0.206 | 0.308 | 0.178 | 0.308 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.013 | -0.237 | -0.046 | 0.218 |
| 02 | -0.446 | -0.357 | -0.81 | 0.795 |
| 03 | -0.474 | -1.625 | -0.21 | 0.863 |
| 04 | 1.32 | -4.185 | -1.549 | -3.482 |
| 05 | -4.049 | 1.376 | -5.484 | -3.929 |
| 06 | -5.484 | -5.484 | 1.383 | -5.484 |
| 07 | -5.484 | 1.383 | -5.484 | -5.484 |
| 08 | -5.484 | 1.383 | -5.484 | -5.484 |
| 09 | -5.484 | 1.375 | -5.484 | -3.348 |
| 10 | -0.379 | -1.909 | -2.244 | 1.119 |
| 11 | 0.796 | -1.77 | -2.203 | 0.407 |
| 12 | 0.653 | -1.334 | -2.859 | 0.565 |
| 13 | 0.08 | -2.183 | -1.489 | 0.947 |
| 14 | 0.296 | -0.931 | -0.877 | 0.613 |
| 15 | 0.364 | -0.507 | 0.09 | -0.146 |
| 16 | -0.715 | -0.482 | 0.905 | -0.866 |
| 17 | -1.096 | -0.218 | 0.933 | -1.143 |
| 18 | -1.469 | 0.601 | 0.547 | -1.518 |
| 19 | -0.995 | 0.801 | -0.03 | -0.84 |
| 20 | -0.592 | 0.307 | 0.162 | -0.092 |
| 21 | -0.19 | 0.207 | -0.34 | 0.209 |
| P-value | Threshold |
|---|---|
| 0.001 | 0.52546 |
| 0.0005 | 2.09956 |
| 0.0001 | 5.38036 |