| Motif | USF2.H14CORE.0.PSM.A |
| Gene (human) | USF2 (GeneCards) |
| Gene synonyms (human) | BHLHB12 |
| Gene (mouse) | Usf2 |
| Gene synonyms (mouse) | |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 0 |
| Quality | A |
| Motif | USF2.H14CORE.0.PSM.A |
| Gene (human) | USF2 (GeneCards) |
| Gene synonyms (human) | BHLHB12 |
| Gene (mouse) | Usf2 |
| Gene synonyms (mouse) | |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 0 |
| Quality | A |
| Motif length | 18 |
| Consensus | nnnnndGTCACGTGvbvn |
| GC content | 59.9% |
| Information content (bits; total / per base) | 15.549 / 0.864 |
| Data sources | ChIP-Seq + HT-SELEX + Methyl-HT-SELEX |
| Aligned words | 823 |
| Previous names | USF2.H12CORE.0.PSM.A |
| ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Human | 14 (93) | 0.984 | 0.995 | 0.966 | 0.988 | 0.978 | 0.994 | 6.069 | 6.92 | 695.638 | 847.215 |
| Mouse | 5 (33) | 0.971 | 0.993 | 0.95 | 0.979 | 0.967 | 0.994 | 5.993 | 6.702 | 515.699 | 870.149 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Overall, 4 experiments | median | 0.999 | 0.998 | 0.997 | 0.995 | 0.949 | 0.951 |
| best | 0.999 | 0.999 | 0.998 | 0.997 | 0.997 | 0.995 | |
| Methyl HT-SELEX, 2 experiments | median | 0.999 | 0.998 | 0.997 | 0.995 | 0.949 | 0.951 |
| best | 0.999 | 0.998 | 0.998 | 0.997 | 0.997 | 0.995 | |
| Non-Methyl HT-SELEX, 2 experiments | median | 0.999 | 0.998 | 0.954 | 0.957 | 0.862 | 0.879 |
| best | 0.999 | 0.999 | 0.998 | 0.997 | 0.997 | 0.995 | |
| rSNP benchmarking, ADASTRA | odds-ratio | -log-Fisher's P | Pearson r | Kendall tau |
|---|---|---|---|---|
| # | 3.678 | 3.672 | 0.173 | 0.12 |
| rSNP benchmarking, SNP-SELEX | auROC | auPRC | Pearson r | Kendall tau |
|---|---|---|---|---|
| batch 2 | 0.928 | 0.589 | 0.847 | 0.62 |
| TF superclass | Basic domains {1} (TFClass) |
| TF class | Basic helix-loop-helix factors (bHLH) {1.2} (TFClass) |
| TF family | bHLH-ZIP {1.2.6} (TFClass) |
| TF subfamily | USF {1.2.6.2} (TFClass) |
| TFClass ID | TFClass: 1.2.6.2.2 |
| HGNC | HGNC:12594 |
| MGI | MGI:99961 |
| EntrezGene (human) | GeneID:7392 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:22282 (SSTAR profile) |
| UniProt ID (human) | USF2_HUMAN |
| UniProt ID (mouse) | USF2_MOUSE |
| UniProt AC (human) | Q15853 (TFClass) |
| UniProt AC (mouse) | Q64705 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 14 human, 5 mouse |
| HT-SELEX | 2 |
| Methyl-HT-SELEX | 2 |
| Genomic HT-SELEX | 0 overall: 0 Lysate, 0 IVT, 0 GFPIVT |
| SMiLE-Seq | 0 |
| PBM | 0 |
| PCM | USF2.H14CORE.0.PSM.A.pcm |
| PWM | USF2.H14CORE.0.PSM.A.pwm |
| PFM | USF2.H14CORE.0.PSM.A.pfm |
| Threshold to P-value map | USF2.H14CORE.0.PSM.A.thr |
| Motif in other formats | |
| JASPAR format | USF2.H14CORE.0.PSM.A_jaspar_format.txt |
| MEME format | USF2.H14CORE.0.PSM.A_meme_format.meme |
| Transfac format | USF2.H14CORE.0.PSM.A_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 174.0 | 202.0 | 295.0 | 152.0 |
| 02 | 152.0 | 243.0 | 258.0 | 170.0 |
| 03 | 129.0 | 270.0 | 238.0 | 186.0 |
| 04 | 136.0 | 274.0 | 239.0 | 174.0 |
| 05 | 165.0 | 222.0 | 291.0 | 145.0 |
| 06 | 257.0 | 65.0 | 362.0 | 139.0 |
| 07 | 84.0 | 10.0 | 728.0 | 1.0 |
| 08 | 6.0 | 10.0 | 13.0 | 794.0 |
| 09 | 0.0 | 823.0 | 0.0 | 0.0 |
| 10 | 820.0 | 0.0 | 1.0 | 2.0 |
| 11 | 1.0 | 781.0 | 7.0 | 34.0 |
| 12 | 70.0 | 1.0 | 752.0 | 0.0 |
| 13 | 3.0 | 1.0 | 2.0 | 817.0 |
| 14 | 0.0 | 0.0 | 822.0 | 1.0 |
| 15 | 388.0 | 95.0 | 272.0 | 68.0 |
| 16 | 39.0 | 348.0 | 167.0 | 269.0 |
| 17 | 112.0 | 379.0 | 247.0 | 85.0 |
| 18 | 198.0 | 247.0 | 208.0 | 170.0 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.211 | 0.245 | 0.358 | 0.185 |
| 02 | 0.185 | 0.295 | 0.313 | 0.207 |
| 03 | 0.157 | 0.328 | 0.289 | 0.226 |
| 04 | 0.165 | 0.333 | 0.29 | 0.211 |
| 05 | 0.2 | 0.27 | 0.354 | 0.176 |
| 06 | 0.312 | 0.079 | 0.44 | 0.169 |
| 07 | 0.102 | 0.012 | 0.885 | 0.001 |
| 08 | 0.007 | 0.012 | 0.016 | 0.965 |
| 09 | 0.0 | 1.0 | 0.0 | 0.0 |
| 10 | 0.996 | 0.0 | 0.001 | 0.002 |
| 11 | 0.001 | 0.949 | 0.009 | 0.041 |
| 12 | 0.085 | 0.001 | 0.914 | 0.0 |
| 13 | 0.004 | 0.001 | 0.002 | 0.993 |
| 14 | 0.0 | 0.0 | 0.999 | 0.001 |
| 15 | 0.471 | 0.115 | 0.33 | 0.083 |
| 16 | 0.047 | 0.423 | 0.203 | 0.327 |
| 17 | 0.136 | 0.461 | 0.3 | 0.103 |
| 18 | 0.241 | 0.3 | 0.253 | 0.207 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | -0.166 | -0.018 | 0.358 | -0.3 |
| 02 | -0.3 | 0.165 | 0.225 | -0.189 |
| 03 | -0.462 | 0.27 | 0.145 | -0.1 |
| 04 | -0.41 | 0.284 | 0.149 | -0.166 |
| 05 | -0.219 | 0.075 | 0.344 | -0.347 |
| 06 | 0.221 | -1.135 | 0.561 | -0.388 |
| 07 | -0.884 | -2.877 | 1.258 | -4.35 |
| 08 | -3.296 | -2.877 | -2.648 | 1.344 |
| 09 | -4.817 | 1.38 | -4.817 | -4.817 |
| 10 | 1.377 | -4.817 | -4.35 | -4.032 |
| 11 | -4.35 | 1.328 | -3.174 | -1.76 |
| 12 | -1.063 | -4.35 | 1.29 | -4.817 |
| 13 | -3.792 | -4.35 | -4.032 | 1.373 |
| 14 | -4.817 | -4.817 | 1.379 | -4.35 |
| 15 | 0.631 | -0.763 | 0.277 | -1.091 |
| 16 | -1.629 | 0.522 | -0.207 | 0.266 |
| 17 | -0.601 | 0.607 | 0.181 | -0.873 |
| 18 | -0.038 | 0.181 | 0.011 | -0.189 |
| P-value | Threshold |
|---|---|
| 0.001 | 1.83116 |
| 0.0005 | 3.30381 |
| 0.0001 | 6.17401 |