TSH2.H14CORE.0.SG.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	TSH2.H14CORE.0.SG.A
Gene (human)	TSHZ2 (GeneCards)
Gene synonyms (human)	C20orf17, TSH2, ZNF218
Gene (mouse)	Tshz2
Gene synonyms (mouse)	Kiaa4248, Sdccag33l, Tsh2, Zfp218, Znf218
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	A

Motif length	15
Consensus	CATCRAATGGAATCR
GC content	39.63%
Information content (bits; total / per base)	25.836 / 1.722
Data sources	HT-SELEX + Genomic HT-SELEX
Aligned words	303
Previous names

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
IVT, 1 experiments	median	0.574	0.551	0.551	0.536	0.533	0.525
IVT, 1 experiments	best	0.574	0.551	0.551	0.536	0.533	0.525

Genomic HT-SELEX benchmarking		Centrality	pseudo-auROC	auROC	auPR
IVT, 1 experiments	median	16.553	0.971	0.65	0.483
IVT, 1 experiments	best	16.553	0.971	0.65	0.483

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Homeo domain factors {3.1} (TFClass)
TF family	HD-ZF {3.1.8} (TFClass)
TF subfamily	TSHZ {3.1.8.2} (TFClass)
TFClass ID	TFClass: 3.1.8.2.2
HGNC	HGNC:13010
MGI	MGI:2153084
EntrezGene (human)	GeneID:128553 (SSTAR profile)
EntrezGene (mouse)	GeneID:228911 (SSTAR profile)
UniProt ID (human)	TSH2_HUMAN
UniProt ID (mouse)	TSH2_MOUSE
UniProt AC (human)	Q9NRE2 (TFClass)
UniProt AC (mouse)	Q68FE9 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 0 mouse
HT-SELEX	1 overall: 0 Lysate, 1 IVT, 0 GFPIVT
Genomic HT-SELEX	1 overall: 0 Lysate, 1 IVT, 0 GFPIVT
SMiLE-Seq	0
PBM	0

PCM	TSH2.H14CORE.0.SG.A.pcm
PWM	TSH2.H14CORE.0.SG.A.pwm
PFM	TSH2.H14CORE.0.SG.A.pfm
Threshold to P-value map	TSH2.H14CORE.0.SG.A.thr
Motif in other formats
JASPAR format	TSH2.H14CORE.0.SG.A_jaspar_format.txt
MEME format	TSH2.H14CORE.0.SG.A_meme_format.meme
Transfac format	TSH2.H14CORE.0.SG.A_transfac_format.txt
Homer format	TSH2.H14CORE.0.SG.A_homer_format_0.001.txt TSH2.H14CORE.0.SG.A_homer_format_0.0005.txt TSH2.H14CORE.0.SG.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	36.0	261.0	4.0	2.0
02	303.0	0.0	0.0	0.0
03	0.0	0.0	2.0	301.0
04	0.0	301.0	1.0	1.0
05	171.0	1.0	131.0	0.0
06	301.0	0.0	1.0	1.0
07	296.0	1.0	5.0	1.0
08	0.0	1.0	0.0	302.0
09	1.0	4.0	298.0	0.0
10	5.0	0.0	298.0	0.0
11	302.0	0.0	0.0	1.0
12	278.0	23.0	1.0	1.0
13	4.0	2.0	0.0	297.0
14	1.0	298.0	2.0	2.0
15	137.0	1.0	165.0	0.0

PFM

	A	C	G	T
01	0.119	0.861	0.013	0.007
02	1.0	0.0	0.0	0.0
03	0.0	0.0	0.007	0.993
04	0.0	0.993	0.003	0.003
05	0.564	0.003	0.432	0.0
06	0.993	0.0	0.003	0.003
07	0.977	0.003	0.017	0.003
08	0.0	0.003	0.0	0.997
09	0.003	0.013	0.983	0.0
10	0.017	0.0	0.983	0.0
11	0.997	0.0	0.0	0.003
12	0.917	0.076	0.003	0.003
13	0.013	0.007	0.0	0.98
14	0.003	0.983	0.007	0.007
15	0.452	0.003	0.545	0.0

PWM

	A	C	G	T
01	-0.724	1.224	-2.654	-3.114
02	1.372	-3.99	-3.99	-3.99
03	-3.99	-3.99	-3.114	1.366
04	-3.99	1.366	-3.459	-3.459
05	0.804	-3.459	0.54	-3.99
06	1.366	-3.99	-3.459	-3.459
07	1.349	-3.459	-2.485	-3.459
08	-3.99	-3.459	-3.99	1.369
09	-3.459	-2.654	1.356	-3.99
10	-2.485	-3.99	1.356	-3.99
11	1.369	-3.99	-3.99	-3.459
12	1.287	-1.15	-3.459	-3.459
13	-2.654	-3.114	-3.99	1.352
14	-3.459	1.356	-3.114	-3.114
15	0.584	-3.459	0.768	-3.99

Standard thresholds

P-value	Threshold
0.001	-4.49299
0.0005	-2.66109
0.0001	1.02507