| Motif | TIGD4.H14RSNP.0.SGI.D |
| Gene (human) | TIGD4 (GeneCards) |
| Gene synonyms (human) | |
| Gene (mouse) | Tigd4 |
| Gene synonyms (mouse) | |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 0 |
| Quality | D |
| Motif | TIGD4.H14RSNP.0.SGI.D |
| Gene (human) | TIGD4 (GeneCards) |
| Gene synonyms (human) | |
| Gene (mouse) | Tigd4 |
| Gene synonyms (mouse) | |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 0 |
| Quality | D |
| Motif length | 18 |
| Consensus | dACCCCGTTAvTAhSMMM |
| GC content | 50.47% |
| Information content (bits; total / per base) | 20.709 / 1.15 |
| Data sources | HT-SELEX + Genomic HT-SELEX + SMiLe-Seq |
| Aligned words | 9267 |
| Previous names |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| overall, 5 experiments | median | 0.916 | 0.918 | 0.707 | 0.735 | 0.595 | 0.634 |
| best | 1.0 | 1.0 | 1.0 | 1.0 | 0.996 | 0.995 | |
| Lysate, 2 experiments | median | 1.0 | 1.0 | 1.0 | 1.0 | 0.947 | 0.954 |
| best | 1.0 | 1.0 | 1.0 | 1.0 | 0.996 | 0.995 | |
| IVT, 1 experiments | median | 0.873 | 0.879 | 0.664 | 0.7 | 0.567 | 0.61 |
| best | 0.873 | 0.879 | 0.664 | 0.7 | 0.567 | 0.61 | |
| GFPIVT, 2 experiments | median | 0.912 | 0.915 | 0.702 | 0.731 | 0.594 | 0.632 |
| best | 0.916 | 0.918 | 0.707 | 0.735 | 0.595 | 0.634 | |
| Genomic HT-SELEX benchmarking | Centrality | pseudo-auROC | auROC | auPR | |
|---|---|---|---|---|---|
| overall, 3 experiments | median | 113.658 | 0.765 | 0.775 | 0.779 |
| best | 473.0 | 0.949 | 0.95 | 0.924 | |
| Lysate, 2 experiments | median | 121.515 | 0.883 | 0.894 | 0.881 |
| best | 473.0 | 0.949 | 0.95 | 0.924 | |
| GFPIVT, 1 experiments | median | 18.081 | 0.544 | 0.631 | 0.568 |
| best | 19.77 | 0.639 | 0.724 | 0.691 | |
| SMiLE-Seq benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Overall, 3 experiments | median | 0.966 | 0.959 | 0.824 | 0.825 | 0.68 | 0.703 |
| best | 0.998 | 0.998 | 0.983 | 0.979 | 0.849 | 0.861 | |
| TF superclass | Helix-turn-helix domains {3} (TFClass) |
| TF class | Other {3.0} (TFClass) |
| TF family | CENPB {3.0.256} (TFClass) |
| TF subfamily | {3.0.256.0} (TFClass) |
| TFClass ID | TFClass: 3.0.256.0.3 |
| HGNC | |
| MGI | |
| EntrezGene (human) | |
| EntrezGene (mouse) | |
| UniProt ID (human) | TIGD4_HUMAN |
| UniProt ID (mouse) | TIGD4_MOUSE |
| UniProt AC (human) | Q8IY51 (TFClass) |
| UniProt AC (mouse) | Q8BUZ3 (TFClass) |
| GRECO-DB-TF | no |
| ChIP-Seq | 0 human, 0 mouse |
| HT-SELEX | 5 overall: 2 Lysate, 1 IVT, 2 GFPIVT |
| Genomic HT-SELEX | 3 overall: 2 Lysate, 0 IVT, 1 GFPIVT |
| SMiLE-Seq | 3 |
| PBM | 0 |
| PCM | TIGD4.H14RSNP.0.SGI.D.pcm |
| PWM | TIGD4.H14RSNP.0.SGI.D.pwm |
| PFM | TIGD4.H14RSNP.0.SGI.D.pfm |
| Threshold to P-value map | TIGD4.H14RSNP.0.SGI.D.thr |
| Motif in other formats | |
| JASPAR format | TIGD4.H14RSNP.0.SGI.D_jaspar_format.txt |
| MEME format | TIGD4.H14RSNP.0.SGI.D_meme_format.meme |
| Transfac format | TIGD4.H14RSNP.0.SGI.D_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 4740.25 | 905.25 | 2508.25 | 1113.25 |
| 02 | 7631.0 | 1037.0 | 547.0 | 52.0 |
| 03 | 115.0 | 9112.0 | 3.0 | 37.0 |
| 04 | 2.0 | 8714.0 | 0.0 | 551.0 |
| 05 | 3.0 | 8671.0 | 4.0 | 589.0 |
| 06 | 1.0 | 7884.0 | 1309.0 | 73.0 |
| 07 | 23.0 | 219.0 | 8996.0 | 29.0 |
| 08 | 1948.0 | 58.0 | 22.0 | 7239.0 |
| 09 | 0.0 | 2.0 | 0.0 | 9265.0 |
| 10 | 9248.0 | 1.0 | 2.0 | 16.0 |
| 11 | 4579.0 | 865.0 | 3285.0 | 538.0 |
| 12 | 64.0 | 966.0 | 323.0 | 7914.0 |
| 13 | 6718.0 | 16.0 | 2526.0 | 7.0 |
| 14 | 1109.0 | 5170.0 | 981.0 | 2007.0 |
| 15 | 724.0 | 2678.0 | 5831.0 | 34.0 |
| 16 | 7279.0 | 1068.0 | 634.0 | 286.0 |
| 17 | 5433.25 | 2630.25 | 485.25 | 718.25 |
| 18 | 1360.0 | 5814.0 | 927.0 | 1166.0 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.512 | 0.098 | 0.271 | 0.12 |
| 02 | 0.823 | 0.112 | 0.059 | 0.006 |
| 03 | 0.012 | 0.983 | 0.0 | 0.004 |
| 04 | 0.0 | 0.94 | 0.0 | 0.059 |
| 05 | 0.0 | 0.936 | 0.0 | 0.064 |
| 06 | 0.0 | 0.851 | 0.141 | 0.008 |
| 07 | 0.002 | 0.024 | 0.971 | 0.003 |
| 08 | 0.21 | 0.006 | 0.002 | 0.781 |
| 09 | 0.0 | 0.0 | 0.0 | 1.0 |
| 10 | 0.998 | 0.0 | 0.0 | 0.002 |
| 11 | 0.494 | 0.093 | 0.354 | 0.058 |
| 12 | 0.007 | 0.104 | 0.035 | 0.854 |
| 13 | 0.725 | 0.002 | 0.273 | 0.001 |
| 14 | 0.12 | 0.558 | 0.106 | 0.217 |
| 15 | 0.078 | 0.289 | 0.629 | 0.004 |
| 16 | 0.785 | 0.115 | 0.068 | 0.031 |
| 17 | 0.586 | 0.284 | 0.052 | 0.078 |
| 18 | 0.147 | 0.627 | 0.1 | 0.126 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.715 | -0.938 | 0.079 | -0.732 |
| 02 | 1.191 | -0.803 | -1.44 | -3.755 |
| 03 | -2.984 | 1.369 | -6.084 | -4.078 |
| 04 | -6.294 | 1.324 | -6.923 | -1.433 |
| 05 | -6.084 | 1.319 | -5.911 | -1.367 |
| 06 | -6.56 | 1.224 | -0.57 | -3.428 |
| 07 | -4.519 | -2.349 | 1.356 | -4.306 |
| 08 | -0.173 | -3.65 | -4.559 | 1.139 |
| 09 | -6.923 | -6.294 | -6.923 | 1.385 |
| 10 | 1.384 | -6.56 | -6.294 | -4.843 |
| 11 | 0.681 | -0.984 | 0.349 | -1.457 |
| 12 | -3.555 | -0.873 | -1.964 | 1.228 |
| 13 | 1.064 | -4.843 | 0.086 | -5.521 |
| 14 | -0.736 | 0.802 | -0.858 | -0.143 |
| 15 | -1.161 | 0.145 | 0.922 | -4.158 |
| 16 | 1.144 | -0.773 | -1.293 | -2.085 |
| 17 | 0.852 | 0.127 | -1.56 | -1.169 |
| 18 | -0.532 | 0.92 | -0.914 | -0.686 |
| P-value | Threshold |
|---|---|
| 0.001 | -2.21209 |
| 0.0005 | -0.37669 |
| 0.0001 | 3.43696 |