MotifTFE3.H14INVITRO.0.PSM.A
Gene (human)TFE3
(GeneCards)
Gene synonyms (human)BHLHE33
Gene (mouse)Tfe3
Gene synonyms (mouse)Tcfe3
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
A
Motif length11
ConsensusnRTCACGTGvn
GC content58.97%
Information content (bits; total / per base)13.767 / 1.252
Data sourcesChIP-Seq + HT-SELEX + Methyl-HT-SELEX
Aligned words9372
Previous namesTFE3.H12INVITRO.0.PSM.A

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 1 (7) 0.793 0.802 0.7 0.717 0.759 0.773 2.557 2.653 241.0 269.509
Mouse 9 (60) 0.992 0.997 0.982 0.992 0.986 0.995 5.591 5.95 546.261 1107.824

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.98 0.973 0.896 0.895 0.815 0.822
best 0.996 0.993 0.995 0.991 0.992 0.986
Methyl HT-SELEX, 1 experiments median 0.996 0.993 0.982 0.976 0.966 0.952
best 0.996 0.993 0.982 0.976 0.966 0.952
Non-Methyl HT-SELEX, 3 experiments median 0.964 0.954 0.81 0.814 0.665 0.692
best 0.996 0.992 0.995 0.991 0.992 0.986

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 1 0.963 0.84 0.929 0.554
batch 2 0.655 0.334 0.627 0.419
TF superclassBasic domains {1} (TFClass)
TF classBasic helix-loop-helix factors (bHLH) {1.2} (TFClass)
TF familybHLH-ZIP {1.2.6} (TFClass)
TF subfamilyTFE3 {1.2.6.1} (TFClass)
TFClass IDTFClass: 1.2.6.1.1
HGNCHGNC:11752
MGIMGI:98511
EntrezGene (human)GeneID:7030
(SSTAR profile)
EntrezGene (mouse)GeneID:209446
(SSTAR profile)
UniProt ID (human)TFE3_HUMAN
UniProt ID (mouse)TFE3_MOUSE
UniProt AC (human)P19532
(TFClass)
UniProt AC (mouse)Q64092
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 1 human, 9 mouse
HT-SELEX 3
Methyl-HT-SELEX 1
Genomic HT-SELEX 0 overall: 0 Lysate, 0 IVT, 0 GFPIVT
SMiLE-Seq 0
PBM 0
PCM
ACGT
012364.02294.02913.01801.0
023615.0770.04932.055.0
0319.0313.01603.07437.0
040.09372.00.00.0
059372.00.00.00.0
060.09372.00.00.0
072.00.09370.00.0
088.093.00.09271.0
094.01.09333.034.0
101916.53680.52437.51337.5
111966.02156.02151.03099.0
PFM
ACGT
010.2520.2450.3110.192
020.3860.0820.5260.006
030.0020.0330.1710.794
040.01.00.00.0
051.00.00.00.0
060.01.00.00.0
070.00.01.00.0
080.0010.010.00.989
090.00.00.9960.004
100.2040.3930.260.143
110.210.230.230.331
PWM
ACGT
010.009-0.0210.218-0.263
020.433-1.1110.744-3.712
03-4.702-2.007-0.3791.154
04-6.9331.386-6.933-6.933
051.386-6.933-6.933-6.933
06-6.9331.386-6.933-6.933
07-6.305-6.9331.385-6.933
08-5.429-3.203-6.9331.375
09-5.922-6.571.381-4.169
10-0.2010.4510.04-0.56
11-0.175-0.083-0.0850.279
Standard thresholds
P-value Threshold
0.001 1.03459
0.0005 2.24969
0.0001 6.734945