TF2L1.H14RSNP.1.P.D motif - HOmo sapiens COmprehensive MOdel COllection

Motif	TF2L1.H14RSNP.1.P.D
Gene (human)	TFCP2L1 (GeneCards)
Gene synonyms (human)	CRTR1, LBP9
Gene (mouse)	Tfcp2l1
Gene synonyms (mouse)	Crtr1, Tcfcp2l1
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	D

Motif length	9
Consensus	vRWCCRGYY
GC content	53.58%
Information content (bits; total / per base)	8.848 / 0.983
Data sources	ChIP-Seq
Aligned words	994
Previous names	TF2L1.H12RSNP.1.P.D

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Mouse	2 (14)	0.818	0.869	0.674	0.742	0.748	0.792	1.988	2.241	103.812	360.155

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 4 experiments	median	0.951	0.921	0.928	0.891	0.882	0.846
Overall, 4 experiments	best	0.957	0.931	0.934	0.901	0.902	0.86
Methyl HT-SELEX, 2 experiments	median	0.954	0.926	0.932	0.897	0.896	0.857
Methyl HT-SELEX, 2 experiments	best	0.957	0.931	0.934	0.901	0.902	0.86
Non-Methyl HT-SELEX, 2 experiments	median	0.937	0.902	0.91	0.868	0.864	0.821
Non-Methyl HT-SELEX, 2 experiments	best	0.95	0.921	0.925	0.889	0.876	0.838

TF superclass	Immunoglobulin fold {6} (TFClass)
TF class	Grainyhead domain factors {6.7} (TFClass)
TF family	CP2-related {6.7.2} (TFClass)
TF subfamily	{6.7.2.0} (TFClass)
TFClass ID	TFClass: 6.7.2.0.2
HGNC	HGNC:17925
MGI	MGI:2444691
EntrezGene (human)	GeneID:29842 (SSTAR profile)
EntrezGene (mouse)	GeneID:81879 (SSTAR profile)
UniProt ID (human)	TF2L1_HUMAN
UniProt ID (mouse)	TF2L1_MOUSE
UniProt AC (human)	Q9NZI6 (TFClass)
UniProt AC (mouse)	Q3UNW5 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 2 mouse
HT-SELEX	2
Methyl-HT-SELEX	2
Genomic HT-SELEX	0 overall: 0 Lysate, 0 IVT, 0 GFPIVT
SMiLE-Seq	0
PBM	0

PCM	TF2L1.H14RSNP.1.P.D.pcm
PWM	TF2L1.H14RSNP.1.P.D.pwm
PFM	TF2L1.H14RSNP.1.P.D.pfm
Threshold to P-value map	TF2L1.H14RSNP.1.P.D.thr
Motif in other formats
JASPAR format	TF2L1.H14RSNP.1.P.D_jaspar_format.txt
MEME format	TF2L1.H14RSNP.1.P.D_meme_format.meme
Transfac format	TF2L1.H14RSNP.1.P.D_transfac_format.txt
Homer format	TF2L1.H14RSNP.1.P.D_homer_format_0.001.txt TF2L1.H14RSNP.1.P.D_homer_format_0.0005.txt TF2L1.H14RSNP.1.P.D_homer_format_0.0001.txt

PCM

	A	C	G	T
01	419.0	109.0	404.0	62.0
02	751.0	29.0	147.0	67.0
03	526.0	11.0	222.0	235.0
04	1.0	975.0	11.0	7.0
05	20.0	955.0	2.0	17.0
06	685.0	2.0	204.0	103.0
07	2.0	10.0	982.0	0.0
08	137.0	311.0	34.0	512.0
09	84.0	340.0	45.0	525.0

PFM

	A	C	G	T
01	0.422	0.11	0.406	0.062
02	0.756	0.029	0.148	0.067
03	0.529	0.011	0.223	0.236
04	0.001	0.981	0.011	0.007
05	0.02	0.961	0.002	0.017
06	0.689	0.002	0.205	0.104
07	0.002	0.01	0.988	0.0
08	0.138	0.313	0.034	0.515
09	0.085	0.342	0.045	0.528

PWM

	A	C	G	T
01	0.52	-0.815	0.483	-1.368
02	1.101	-2.097	-0.52	-1.292
03	0.746	-2.979	-0.112	-0.055
04	-4.52	1.362	-2.979	-3.356
05	-2.444	1.341	-4.207	-2.592
06	1.01	-4.207	-0.196	-0.871
07	-4.207	-3.061	1.369	-4.977
08	-0.59	0.223	-1.946	0.719
09	-1.071	0.312	-1.678	0.744

Standard thresholds

P-value	Threshold
0.001	5.15061
0.0005	5.95192
0.0001	7.266715