TAL1.H14RSNP.1.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	TAL1.H14RSNP.1.P.B
Gene (human)	TAL1 (GeneCards)
Gene synonyms (human)	BHLHA17, SCL, TCL5
Gene (mouse)	Tal1
Gene synonyms (mouse)	Scl, Tal-1
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	B

Motif length	14
Consensus	dvhdvSAGMWRdbv
GC content	49.4%
Information content (bits; total / per base)	7.455 / 0.533
Data sources	ChIP-Seq
Aligned words	1015
Previous names	TAL1.H12RSNP.1.P.B

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	27 (163)	0.716	0.755	0.534	0.58	0.714	0.74	1.853	2.001	35.18	65.77
Mouse	33 (190)	0.701	0.755	0.511	0.58	0.704	0.745	1.789	2.017	29.262	55.167

rSNP benchmarking, ADASTRA	odds-ratio	-log-Fisher's P	Pearson r	Kendall tau
#	2.107	3.339	0.142	0.114

TF superclass	Basic domains {1} (TFClass)
TF class	Basic helix-loop-helix factors (bHLH) {1.2} (TFClass)
TF family	Tal-related {1.2.3} (TFClass)
TF subfamily	TAL-HEN {1.2.3.1} (TFClass)
TFClass ID	TFClass: 1.2.3.1.1
HGNC	HGNC:11556
MGI	MGI:98480
EntrezGene (human)	GeneID:6886 (SSTAR profile)
EntrezGene (mouse)	GeneID:21349 (SSTAR profile)
UniProt ID (human)	TAL1_HUMAN
UniProt ID (mouse)	TAL1_MOUSE
UniProt AC (human)	P17542 (TFClass)
UniProt AC (mouse)	P22091 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	27 human, 33 mouse
HT-SELEX	0
Methyl-HT-SELEX	0
Genomic HT-SELEX	0 overall: 0 Lysate, 0 IVT, 0 GFPIVT
SMiLE-Seq	0
PBM	0

PCM	TAL1.H14RSNP.1.P.B.pcm
PWM	TAL1.H14RSNP.1.P.B.pwm
PFM	TAL1.H14RSNP.1.P.B.pfm
Threshold to P-value map	TAL1.H14RSNP.1.P.B.thr
Motif in other formats
JASPAR format	TAL1.H14RSNP.1.P.B_jaspar_format.txt
MEME format	TAL1.H14RSNP.1.P.B_meme_format.meme
Transfac format	TAL1.H14RSNP.1.P.B_transfac_format.txt
Homer format	TAL1.H14RSNP.1.P.B_homer_format_0.001.txt TAL1.H14RSNP.1.P.B_homer_format_0.0005.txt TAL1.H14RSNP.1.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	347.0	89.0	404.0	175.0
02	206.0	249.0	458.0	102.0
03	467.0	192.0	153.0	203.0
04	397.0	116.0	314.0	188.0
05	409.0	102.0	417.0	87.0
06	78.0	730.0	198.0	9.0
07	803.0	4.0	11.0	197.0
08	1.0	37.0	969.0	8.0
09	560.0	312.0	136.0	7.0
10	289.0	32.0	9.0	685.0
11	429.0	36.0	527.0	23.0
12	442.0	48.0	284.0	241.0
13	117.0	198.0	497.0	203.0
14	408.0	210.0	288.0	109.0

PFM

	A	C	G	T
01	0.342	0.088	0.398	0.172
02	0.203	0.245	0.451	0.1
03	0.46	0.189	0.151	0.2
04	0.391	0.114	0.309	0.185
05	0.403	0.1	0.411	0.086
06	0.077	0.719	0.195	0.009
07	0.791	0.004	0.011	0.194
08	0.001	0.036	0.955	0.008
09	0.552	0.307	0.134	0.007
10	0.285	0.032	0.009	0.675
11	0.423	0.035	0.519	0.023
12	0.435	0.047	0.28	0.237
13	0.115	0.195	0.49	0.2
14	0.402	0.207	0.284	0.107

PWM

	A	C	G	T
01	0.311	-1.035	0.463	-0.369
02	-0.207	-0.019	0.587	-0.901
03	0.607	-0.277	-0.501	-0.221
04	0.445	-0.775	0.212	-0.298
05	0.475	-0.901	0.494	-1.058
06	-1.164	1.052	-0.246	-3.17
07	1.147	-3.797	-2.999	-0.251
08	-4.539	-1.887	1.335	-3.268
09	0.788	0.205	-0.618	-3.376
10	0.129	-2.025	-3.17	0.989
11	0.522	-1.913	0.727	-2.335
12	0.552	-1.637	0.112	-0.051
13	-0.766	-0.246	0.669	-0.221
14	0.472	-0.188	0.126	-0.836

Standard thresholds

P-value	Threshold
0.001	5.14791
0.0005	5.76546
0.0001	6.94171