| Motif | SRF.H14CORE.0.PSM.A |
| Gene (human) | SRF (GeneCards) |
| Gene synonyms (human) | |
| Gene (mouse) | Srf |
| Gene synonyms (mouse) | |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 0 |
| Quality | A |
| Motif | SRF.H14CORE.0.PSM.A |
| Gene (human) | SRF (GeneCards) |
| Gene synonyms (human) | |
| Gene (mouse) | Srf |
| Gene synonyms (mouse) | |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 0 |
| Quality | A |
| Motif length | 17 |
| Consensus | hbnCCWTWTWTGGnhdd |
| GC content | 41.52% |
| Information content (bits; total / per base) | 14.735 / 0.867 |
| Data sources | ChIP-Seq + HT-SELEX + Methyl-HT-SELEX |
| Aligned words | 948 |
| Previous names | SRF.H12CORE.0.PSM.A |
| ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Human | 21 (147) | 0.823 | 0.986 | 0.821 | 0.973 | 0.793 | 0.979 | 4.267 | 6.2 | 441.432 | 960.367 |
| Mouse | 19 (113) | 0.914 | 0.98 | 0.902 | 0.966 | 0.891 | 0.975 | 4.869 | 6.587 | 274.051 | 697.62 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Overall, 5 experiments | median | 0.656 | 0.69 | 0.556 | 0.589 | 0.517 | 0.546 |
| best | 0.988 | 0.978 | 0.982 | 0.969 | 0.944 | 0.93 | |
| Methyl HT-SELEX, 1 experiments | median | 0.988 | 0.978 | 0.982 | 0.969 | 0.944 | 0.93 |
| best | 0.988 | 0.978 | 0.982 | 0.969 | 0.944 | 0.93 | |
| Non-Methyl HT-SELEX, 4 experiments | median | 0.619 | 0.643 | 0.545 | 0.568 | 0.516 | 0.536 |
| best | 0.981 | 0.964 | 0.971 | 0.953 | 0.931 | 0.91 | |
| rSNP benchmarking, ADASTRA | odds-ratio | -log-Fisher's P | Pearson r | Kendall tau |
|---|---|---|---|---|
| # | 5.769 | 6.179 | 0.409 | 0.262 |
| rSNP benchmarking, SNP-SELEX | auROC | auPRC | Pearson r | Kendall tau |
|---|---|---|---|---|
| batch 2 | 0.821 | 0.08 | 0.75 | 0.333 |
| TF superclass | alpha-Helices exposed by beta-structures {5} (TFClass) |
| TF class | MADS box factors {5.1} (TFClass) |
| TF family | Responders to external signals {5.1.2} (TFClass) |
| TF subfamily | {5.1.2.0} (TFClass) |
| TFClass ID | TFClass: 5.1.2.0.1 |
| HGNC | HGNC:11291 |
| MGI | MGI:106658 |
| EntrezGene (human) | GeneID:6722 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:20807 (SSTAR profile) |
| UniProt ID (human) | SRF_HUMAN |
| UniProt ID (mouse) | SRF_MOUSE |
| UniProt AC (human) | P11831 (TFClass) |
| UniProt AC (mouse) | Q9JM73 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 21 human, 19 mouse |
| HT-SELEX | 4 |
| Methyl-HT-SELEX | 1 |
| Genomic HT-SELEX | 0 overall: 0 Lysate, 0 IVT, 0 GFPIVT |
| SMiLE-Seq | 0 |
| PBM | 0 |
| PCM | SRF.H14CORE.0.PSM.A.pcm |
| PWM | SRF.H14CORE.0.PSM.A.pwm |
| PFM | SRF.H14CORE.0.PSM.A.pfm |
| Threshold to P-value map | SRF.H14CORE.0.PSM.A.thr |
| Motif in other formats | |
| JASPAR format | SRF.H14CORE.0.PSM.A_jaspar_format.txt |
| MEME format | SRF.H14CORE.0.PSM.A_meme_format.meme |
| Transfac format | SRF.H14CORE.0.PSM.A_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 142.0 | 163.0 | 85.0 | 558.0 |
| 02 | 73.0 | 134.0 | 200.0 | 541.0 |
| 03 | 218.0 | 155.0 | 292.0 | 283.0 |
| 04 | 10.0 | 921.0 | 11.0 | 6.0 |
| 05 | 0.0 | 906.0 | 0.0 | 42.0 |
| 06 | 267.0 | 143.0 | 17.0 | 521.0 |
| 07 | 100.0 | 31.0 | 20.0 | 797.0 |
| 08 | 682.0 | 16.0 | 39.0 | 211.0 |
| 09 | 17.0 | 28.0 | 10.0 | 893.0 |
| 10 | 594.0 | 20.0 | 9.0 | 325.0 |
| 11 | 100.0 | 12.0 | 15.0 | 821.0 |
| 12 | 92.0 | 0.0 | 855.0 | 1.0 |
| 13 | 8.0 | 10.0 | 919.0 | 11.0 |
| 14 | 117.0 | 276.0 | 279.0 | 276.0 |
| 15 | 176.0 | 539.0 | 92.0 | 141.0 |
| 16 | 409.0 | 88.0 | 114.0 | 337.0 |
| 17 | 262.0 | 129.0 | 163.0 | 394.0 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.15 | 0.172 | 0.09 | 0.589 |
| 02 | 0.077 | 0.141 | 0.211 | 0.571 |
| 03 | 0.23 | 0.164 | 0.308 | 0.299 |
| 04 | 0.011 | 0.972 | 0.012 | 0.006 |
| 05 | 0.0 | 0.956 | 0.0 | 0.044 |
| 06 | 0.282 | 0.151 | 0.018 | 0.55 |
| 07 | 0.105 | 0.033 | 0.021 | 0.841 |
| 08 | 0.719 | 0.017 | 0.041 | 0.223 |
| 09 | 0.018 | 0.03 | 0.011 | 0.942 |
| 10 | 0.627 | 0.021 | 0.009 | 0.343 |
| 11 | 0.105 | 0.013 | 0.016 | 0.866 |
| 12 | 0.097 | 0.0 | 0.902 | 0.001 |
| 13 | 0.008 | 0.011 | 0.969 | 0.012 |
| 14 | 0.123 | 0.291 | 0.294 | 0.291 |
| 15 | 0.186 | 0.569 | 0.097 | 0.149 |
| 16 | 0.431 | 0.093 | 0.12 | 0.355 |
| 17 | 0.276 | 0.136 | 0.172 | 0.416 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | -0.507 | -0.371 | -1.013 | 0.852 |
| 02 | -1.162 | -0.565 | -0.168 | 0.821 |
| 03 | -0.083 | -0.421 | 0.207 | 0.176 |
| 04 | -3.015 | 1.352 | -2.933 | -3.432 |
| 05 | -4.937 | 1.336 | -4.937 | -1.698 |
| 06 | 0.118 | -0.501 | -2.546 | 0.784 |
| 07 | -0.853 | -1.987 | -2.397 | 1.208 |
| 08 | 1.052 | -2.601 | -1.769 | -0.115 |
| 09 | -2.546 | -2.084 | -3.015 | 1.321 |
| 10 | 0.914 | -2.397 | -3.104 | 0.314 |
| 11 | -0.853 | -2.857 | -2.659 | 1.237 |
| 12 | -0.935 | -4.937 | 1.278 | -4.477 |
| 13 | -3.202 | -3.015 | 1.35 | -2.933 |
| 14 | -0.699 | 0.151 | 0.162 | 0.151 |
| 15 | -0.295 | 0.818 | -0.935 | -0.514 |
| 16 | 0.543 | -0.979 | -0.724 | 0.35 |
| 17 | 0.1 | -0.602 | -0.371 | 0.505 |
| P-value | Threshold |
|---|---|
| 0.001 | 3.08091 |
| 0.0005 | 4.24131 |
| 0.0001 | 6.65706 |