SPI1.H14INVITRO.1.S.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	SPI1.H14INVITRO.1.S.B
Gene (human)	SPI1 (GeneCards)
Gene synonyms (human)
Gene (mouse)	Spi1
Gene synonyms (mouse)	Sfpi-1, Sfpi1
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	B

Motif length	10
Consensus	ddvGGAARdn
GC content	53.54%
Information content (bits; total / per base)	9.321 / 0.932
Data sources	HT-SELEX
Aligned words	7583
Previous names	SPI1.H12INVITRO.1.S.B

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	94 (173)	0.924	0.966	0.842	0.929	0.902	0.954	3.248	3.744	382.009	685.824
Mouse	158 (286)	0.918	0.955	0.835	0.927	0.904	0.94	3.273	3.671	389.508	668.796

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 2 experiments	median	0.623	0.599	0.553	0.554	0.514	0.528
Non-Methyl HT-SELEX, 2 experiments	best	0.656	0.63	0.573	0.572	0.525	0.539

rSNP benchmarking, ADASTRA	odds-ratio	-log-Fisher's P	Pearson r	Kendall tau
#	2.591	77.915	0.293	0.201

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Tryptophan cluster factors {3.5} (TFClass)
TF family	Ets-related {3.5.2} (TFClass)
TF subfamily	SPI-like {3.5.2.5} (TFClass)
TFClass ID	TFClass: 3.5.2.5.1
HGNC	HGNC:11241
MGI	MGI:98282
EntrezGene (human)	GeneID:6688 (SSTAR profile)
EntrezGene (mouse)	GeneID:20375 (SSTAR profile)
UniProt ID (human)	SPI1_HUMAN
UniProt ID (mouse)	SPI1_MOUSE
UniProt AC (human)	P17947 (TFClass)
UniProt AC (mouse)	P17433 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	94 human, 158 mouse
HT-SELEX	2
Methyl-HT-SELEX	0
Genomic HT-SELEX	0 overall: 0 Lysate, 0 IVT, 0 GFPIVT
SMiLE-Seq	0
PBM	0

PCM	SPI1.H14INVITRO.1.S.B.pcm
PWM	SPI1.H14INVITRO.1.S.B.pwm
PFM	SPI1.H14INVITRO.1.S.B.pfm
Threshold to P-value map	SPI1.H14INVITRO.1.S.B.thr
Motif in other formats
JASPAR format	SPI1.H14INVITRO.1.S.B_jaspar_format.txt
MEME format	SPI1.H14INVITRO.1.S.B_meme_format.meme
Transfac format	SPI1.H14INVITRO.1.S.B_transfac_format.txt
Homer format	SPI1.H14INVITRO.1.S.B_homer_format_0.001.txt SPI1.H14INVITRO.1.S.B_homer_format_0.0005.txt SPI1.H14INVITRO.1.S.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	2408.0	752.0	2255.0	2168.0
02	1208.5	951.5	4167.5	1255.5
03	1772.0	1825.0	3650.0	336.0
04	104.0	162.0	7224.0	93.0
05	0.0	0.0	7583.0	0.0
06	7580.0	0.0	0.0	3.0
07	7485.0	4.0	80.0	14.0
08	882.0	862.0	5451.0	388.0
09	1174.5	924.5	1424.5	4059.5
10	2552.5	1024.5	2258.5	1747.5

PFM

	A	C	G	T
01	0.318	0.099	0.297	0.286
02	0.159	0.125	0.55	0.166
03	0.234	0.241	0.481	0.044
04	0.014	0.021	0.953	0.012
05	0.0	0.0	1.0	0.0
06	1.0	0.0	0.0	0.0
07	0.987	0.001	0.011	0.002
08	0.116	0.114	0.719	0.051
09	0.155	0.122	0.188	0.535
10	0.337	0.135	0.298	0.23

PWM

	A	C	G	T
01	0.239	-0.923	0.173	0.134
02	-0.45	-0.688	0.787	-0.411
03	-0.067	-0.038	0.655	-1.725
04	-2.883	-2.447	1.337	-2.992
05	-6.745	-6.745	1.385	-6.745
06	1.385	-6.745	-6.745	-5.893
07	1.372	-5.719	-3.139	-4.761
08	-0.764	-0.787	1.055	-1.582
09	-0.478	-0.717	-0.285	0.761
10	0.297	-0.614	0.175	-0.081

Standard thresholds

P-value	Threshold
0.001	5.261535
0.0005	6.05085
0.0001	7.355135