SPI1.H14INVITRO.0.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	SPI1.H14INVITRO.0.P.B
Gene (human)	SPI1 (GeneCards)
Gene synonyms (human)
Gene (mouse)	Spi1
Gene synonyms (mouse)	Sfpi-1, Sfpi1
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	14
Consensus	vRRRRRGGAAGTGv
GC content	49.68%
Information content (bits; total / per base)	14.993 / 1.071
Data sources	ChIP-Seq
Aligned words	999
Previous names	SPI1.H12INVITRO.0.P.B

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	94 (173)	0.971	0.991	0.944	0.979	0.974	0.994	5.579	7.257	563.745	975.114
Mouse	158 (286)	0.976	0.992	0.954	0.988	0.979	0.995	5.589	7.154	575.732	929.745

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 2 experiments	median	0.601	0.594	0.541	0.548	0.517	0.526
Non-Methyl HT-SELEX, 2 experiments	best	0.632	0.625	0.557	0.565	0.524	0.536

rSNP benchmarking, ADASTRA	odds-ratio	-log-Fisher's P	Pearson r	Kendall tau
#	4.953	193.416	0.385	0.29

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Tryptophan cluster factors {3.5} (TFClass)
TF family	Ets-related {3.5.2} (TFClass)
TF subfamily	SPI-like {3.5.2.5} (TFClass)
TFClass ID	TFClass: 3.5.2.5.1
HGNC	HGNC:11241
MGI	MGI:98282
EntrezGene (human)	GeneID:6688 (SSTAR profile)
EntrezGene (mouse)	GeneID:20375 (SSTAR profile)
UniProt ID (human)	SPI1_HUMAN
UniProt ID (mouse)	SPI1_MOUSE
UniProt AC (human)	P17947 (TFClass)
UniProt AC (mouse)	P17433 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	94 human, 158 mouse
HT-SELEX	2
Methyl-HT-SELEX	0
Genomic HT-SELEX	0 overall: 0 Lysate, 0 IVT, 0 GFPIVT
SMiLE-Seq	0
PBM	0

PCM	SPI1.H14INVITRO.0.P.B.pcm
PWM	SPI1.H14INVITRO.0.P.B.pwm
PFM	SPI1.H14INVITRO.0.P.B.pfm
Threshold to P-value map	SPI1.H14INVITRO.0.P.B.thr
Motif in other formats
JASPAR format	SPI1.H14INVITRO.0.P.B_jaspar_format.txt
MEME format	SPI1.H14INVITRO.0.P.B_meme_format.meme
Transfac format	SPI1.H14INVITRO.0.P.B_transfac_format.txt
Homer format	SPI1.H14INVITRO.0.P.B_homer_format_0.001.txt SPI1.H14INVITRO.0.P.B_homer_format_0.0005.txt SPI1.H14INVITRO.0.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	369.0	179.0	349.0	102.0
02	629.0	58.0	197.0	115.0
03	507.0	55.0	357.0	80.0
04	616.0	13.0	188.0	182.0
05	189.0	79.0	715.0	16.0
06	667.0	68.0	261.0	3.0
07	62.0	0.0	936.0	1.0
08	1.0	0.0	998.0	0.0
09	998.0	1.0	0.0	0.0
10	996.0	0.0	0.0	3.0
11	30.0	139.0	830.0	0.0
12	37.0	41.0	7.0	914.0
13	37.0	88.0	853.0	21.0
14	368.0	216.0	320.0	95.0

PFM

	A	C	G	T
01	0.369	0.179	0.349	0.102
02	0.63	0.058	0.197	0.115
03	0.508	0.055	0.357	0.08
04	0.617	0.013	0.188	0.182
05	0.189	0.079	0.716	0.016
06	0.668	0.068	0.261	0.003
07	0.062	0.0	0.937	0.001
08	0.001	0.0	0.999	0.0
09	0.999	0.001	0.0	0.0
10	0.997	0.0	0.0	0.003
11	0.03	0.139	0.831	0.0
12	0.037	0.041	0.007	0.915
13	0.037	0.088	0.854	0.021
14	0.368	0.216	0.32	0.095

PWM

	A	C	G	T
01	0.388	-0.33	0.333	-0.886
02	0.92	-1.438	-0.235	-0.768
03	0.705	-1.489	0.355	-1.124
04	0.899	-2.838	-0.282	-0.314
05	-0.277	-1.136	1.047	-2.652
06	0.978	-1.283	0.044	-3.974
07	-1.373	-4.981	1.316	-4.524
08	-4.524	-4.981	1.38	-4.981
09	1.38	-4.524	-4.981	-4.981
10	1.378	-4.981	-4.981	-3.974
11	-2.07	-0.581	1.196	-4.981
12	-1.871	-1.773	-3.361	1.292
13	-1.871	-1.031	1.223	-2.404
14	0.385	-0.144	0.246	-0.955

Standard thresholds

P-value	Threshold
0.001	2.57181
0.0005	3.89801
0.0001	6.60032