SP2.H14INVIVO.0.P.D motif - HOmo sapiens COmprehensive MOdel COllection

Motif	SP2.H14INVIVO.0.P.D
Gene (human)	SP2 (GeneCards)
Gene synonyms (human)	KIAA0048
Gene (mouse)	Sp2
Gene synonyms (mouse)	Kiaa0048
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	D

Motif length	12
Consensus	dRRGGGCGGGRM
GC content	79.15%
Information content (bits; total / per base)	13.708 / 1.142
Data sources	ChIP-Seq
Aligned words	498
Previous names	SP2.H12INVIVO.0.P.D; SP2_HUMAN.H11MO.1.B

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	5 (33)	0.73	0.895	0.559	0.775	0.806	0.921	2.761	3.643	22.398	126.268

rSNP benchmarking, ADASTRA	odds-ratio	-log-Fisher's P	Pearson r	Kendall tau
#	1.438	1.428	0.048	0.027

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	Three-zinc finger Kruppel-related {2.3.1} (TFClass)
TF subfamily	Sp1-like {2.3.1.1} (TFClass)
TFClass ID	TFClass: 2.3.1.1.2
HGNC	HGNC:11207
MGI	MGI:1926162
EntrezGene (human)	GeneID:6668 (SSTAR profile)
EntrezGene (mouse)	GeneID:78912 (SSTAR profile)
UniProt ID (human)	SP2_HUMAN
UniProt ID (mouse)	SP2_MOUSE
UniProt AC (human)	Q02086 (TFClass)
UniProt AC (mouse)	Q9D2H6 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	5 human, 0 mouse
HT-SELEX	0
Methyl-HT-SELEX	0
Genomic HT-SELEX	0 overall: 0 Lysate, 0 IVT, 0 GFPIVT
SMiLE-Seq	0
PBM	0

PCM	SP2.H14INVIVO.0.P.D.pcm
PWM	SP2.H14INVIVO.0.P.D.pwm
PFM	SP2.H14INVIVO.0.P.D.pfm
Threshold to P-value map	SP2.H14INVIVO.0.P.D.thr
Motif in other formats
JASPAR format	SP2.H14INVIVO.0.P.D_jaspar_format.txt
MEME format	SP2.H14INVIVO.0.P.D_meme_format.meme
Transfac format	SP2.H14INVIVO.0.P.D_transfac_format.txt
Homer format	SP2.H14INVIVO.0.P.D_homer_format_0.001.txt SP2.H14INVIVO.0.P.D_homer_format_0.0005.txt SP2.H14INVIVO.0.P.D_homer_format_0.0001.txt

PCM

	A	C	G	T
01	224.0	41.0	172.0	61.0
02	129.0	16.0	333.0	20.0
03	75.0	3.0	368.0	52.0
04	178.0	0.0	320.0	0.0
05	2.0	2.0	494.0	0.0
06	1.0	2.0	493.0	2.0
07	79.0	385.0	0.0	34.0
08	11.0	6.0	470.0	11.0
09	3.0	1.0	483.0	11.0
10	49.0	10.0	410.0	29.0
11	114.0	17.0	345.0	22.0
12	119.0	320.0	39.0	20.0

PFM

	A	C	G	T
01	0.45	0.082	0.345	0.122
02	0.259	0.032	0.669	0.04
03	0.151	0.006	0.739	0.104
04	0.357	0.0	0.643	0.0
05	0.004	0.004	0.992	0.0
06	0.002	0.004	0.99	0.004
07	0.159	0.773	0.0	0.068
08	0.022	0.012	0.944	0.022
09	0.006	0.002	0.97	0.022
10	0.098	0.02	0.823	0.058
11	0.229	0.034	0.693	0.044
12	0.239	0.643	0.078	0.04

PWM

	A	C	G	T
01	0.582	-1.086	0.32	-0.701
02	0.035	-1.971	0.976	-1.766
03	-0.499	-3.321	1.076	-0.856
04	0.354	-4.397	0.936	-4.397
05	-3.569	-3.569	1.369	-4.397
06	-3.9	-3.569	1.367	-3.569
07	-0.448	1.121	-4.397	-1.266
08	-2.307	-2.815	1.319	-2.307
09	-3.321	-3.9	1.347	-2.307
10	-0.914	-2.39	1.183	-1.417
11	-0.087	-1.916	1.011	-1.677
12	-0.045	0.936	-1.134	-1.766

Standard thresholds

P-value	Threshold
0.001	3.517675
0.0005	4.65409
0.0001	6.962235