SP100.H14INVIVO.0.PSGI.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	SP100.H14INVIVO.0.PSGI.A
Gene (human)	SP100 (GeneCards)
Gene synonyms (human)
Gene (mouse)	Sp100
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	A

Motif length	13
Consensus	ndhWvCGGTYAdn
GC content	45.57%
Information content (bits; total / per base)	10.665 / 0.82
Data sources	ChIP-Seq + HT-SELEX + Genomic HT-SELEX + SMiLe-Seq
Aligned words	1554
Previous names

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	Centrality, median	Centrality, best
Overall	2 (2)	0.682	0.687	0.478	0.478	0.374	0.385	2.178	2.26

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
GFPIVT, 1 experiments	median	0.886	0.836	0.823	0.775	0.751	0.713
GFPIVT, 1 experiments	best	0.886	0.836	0.823	0.775	0.751	0.713

Genomic HT-SELEX benchmarking		Centrality	pseudo-auROC	auROC	auPR
GFPIVT, 1 experiments	median	11.715	0.35	0.621	0.455
GFPIVT, 1 experiments	best	23.194	0.391	0.651	0.484

SMiLE-Seq benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 1 experiments	median	0.746	0.681	0.688	0.639	0.635	0.604
Overall, 1 experiments	best	0.746	0.681	0.688	0.639	0.635	0.604

TF superclass	alpha-Helices exposed by beta-structures {5} (TFClass)
TF class	SAND domain factors {5.3} (TFClass)
TF family	Sp140-Sp100 {5.3.5} (TFClass)
TF subfamily	Sp100 {5.3.5.2} (TFClass)
TFClass ID	TFClass: 5.3.5.2.1
HGNC	HGNC:11206
MGI	MGI:109561
EntrezGene (human)	GeneID:6672 (SSTAR profile)
EntrezGene (mouse)	GeneID:20684 (SSTAR profile)
UniProt ID (human)	SP100_HUMAN
UniProt ID (mouse)	SP100_MOUSE
UniProt AC (human)	P23497 (TFClass)
UniProt AC (mouse)	O35892 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	2 human, 0 mouse
HT-SELEX	1 overall: 0 Lysate, 0 IVT, 1 GFPIVT
Genomic HT-SELEX	1 overall: 0 Lysate, 0 IVT, 1 GFPIVT
SMiLE-Seq	1
PBM	0

PCM	SP100.H14INVIVO.0.PSGI.A.pcm
PWM	SP100.H14INVIVO.0.PSGI.A.pwm
PFM	SP100.H14INVIVO.0.PSGI.A.pfm
Threshold to P-value map	SP100.H14INVIVO.0.PSGI.A.thr
Motif in other formats
JASPAR format	SP100.H14INVIVO.0.PSGI.A_jaspar_format.txt
MEME format	SP100.H14INVIVO.0.PSGI.A_meme_format.meme
Transfac format	SP100.H14INVIVO.0.PSGI.A_transfac_format.txt
Homer format	SP100.H14INVIVO.0.PSGI.A_homer_format_0.001.txt SP100.H14INVIVO.0.PSGI.A_homer_format_0.0005.txt SP100.H14INVIVO.0.PSGI.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	289.25	322.25	400.25	542.25
02	400.5	216.5	219.5	717.5
03	470.0	180.0	179.0	725.0
04	745.0	12.0	321.0	476.0
05	595.0	388.0	342.0	229.0
06	0.0	1554.0	0.0	0.0
07	0.0	0.0	1554.0	0.0
08	0.0	0.0	1554.0	0.0
09	2.0	354.0	0.0	1198.0
10	240.0	322.0	3.0	989.0
11	1375.0	7.0	21.0	151.0
12	882.25	137.25	235.25	299.25
13	335.25	461.25	422.25	335.25

PFM

	A	C	G	T
01	0.186	0.207	0.258	0.349
02	0.258	0.139	0.141	0.462
03	0.302	0.116	0.115	0.467
04	0.479	0.008	0.207	0.306
05	0.383	0.25	0.22	0.147
06	0.0	1.0	0.0	0.0
07	0.0	0.0	1.0	0.0
08	0.0	0.0	1.0	0.0
09	0.001	0.228	0.0	0.771
10	0.154	0.207	0.002	0.636
11	0.885	0.005	0.014	0.097
12	0.568	0.088	0.151	0.193
13	0.216	0.297	0.272	0.216

PWM

	A	C	G	T
01	-0.293	-0.186	0.03	0.332
02	0.03	-0.581	-0.567	0.611
03	0.19	-0.764	-0.769	0.622
04	0.649	-3.34	-0.19	0.202
05	0.425	-0.001	-0.127	-0.525
06	-5.359	1.383	-5.359	-5.359
07	-5.359	-5.359	1.383	-5.359
08	-5.359	-5.359	1.383	-5.359
09	-4.622	-0.093	-5.359	1.123
10	-0.479	-0.187	-4.391	0.932
11	1.261	-3.788	-2.839	-0.938
12	0.818	-1.032	-0.499	-0.26
13	-0.147	0.171	0.083	-0.147

Standard thresholds

P-value	Threshold
0.001	4.76276
0.0005	5.90201
0.0001	7.59675