SP100.H14CORE.0.PSGI.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	SP100.H14CORE.0.PSGI.A
Gene (human)	SP100 (GeneCards)
Gene synonyms (human)
Gene (mouse)	Sp100
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	A

Motif length	11
Consensus	hdWvCGGYhWd
GC content	46.82%
Information content (bits; total / per base)	9.049 / 0.823
Data sources	ChIP-Seq + HT-SELEX + Genomic HT-SELEX + SMiLe-Seq
Aligned words	7528
Previous names

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	Centrality, median	Centrality, best
Overall	2 (2)	0.684	0.691	0.472	0.475	0.362	0.373	3.351	5.081

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
GFPIVT, 1 experiments	median	0.892	0.842	0.837	0.786	0.768	0.726
GFPIVT, 1 experiments	best	0.892	0.842	0.837	0.786	0.768	0.726

Genomic HT-SELEX benchmarking		Centrality	pseudo-auROC	auROC	auPR
GFPIVT, 1 experiments	median	13.551	0.36	0.658	0.486
GFPIVT, 1 experiments	best	26.215	0.39	0.674	0.506

SMiLE-Seq benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 1 experiments	median	0.754	0.688	0.694	0.644	0.641	0.609
Overall, 1 experiments	best	0.754	0.688	0.694	0.644	0.641	0.609

TF superclass	alpha-Helices exposed by beta-structures {5} (TFClass)
TF class	SAND domain factors {5.3} (TFClass)
TF family	Sp140-Sp100 {5.3.5} (TFClass)
TF subfamily	Sp100 {5.3.5.2} (TFClass)
TFClass ID	TFClass: 5.3.5.2.1
HGNC	HGNC:11206
MGI	MGI:109561
EntrezGene (human)	GeneID:6672 (SSTAR profile)
EntrezGene (mouse)	GeneID:20684 (SSTAR profile)
UniProt ID (human)	SP100_HUMAN
UniProt ID (mouse)	SP100_MOUSE
UniProt AC (human)	P23497 (TFClass)
UniProt AC (mouse)	O35892 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	2 human, 0 mouse
HT-SELEX	1 overall: 0 Lysate, 0 IVT, 1 GFPIVT
Genomic HT-SELEX	1 overall: 0 Lysate, 0 IVT, 1 GFPIVT
SMiLE-Seq	1
PBM	0

PCM	SP100.H14CORE.0.PSGI.A.pcm
PWM	SP100.H14CORE.0.PSGI.A.pwm
PFM	SP100.H14CORE.0.PSGI.A.pfm
Threshold to P-value map	SP100.H14CORE.0.PSGI.A.thr
Motif in other formats
JASPAR format	SP100.H14CORE.0.PSGI.A_jaspar_format.txt
MEME format	SP100.H14CORE.0.PSGI.A_meme_format.meme
Transfac format	SP100.H14CORE.0.PSGI.A_transfac_format.txt
Homer format	SP100.H14CORE.0.PSGI.A_homer_format_0.001.txt SP100.H14CORE.0.PSGI.A_homer_format_0.0005.txt SP100.H14CORE.0.PSGI.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	1985.75	1196.75	1169.75	3175.75
02	2154.5	1046.5	1120.5	3206.5
03	3333.0	41.0	1290.0	2864.0
04	3328.0	1323.0	1704.0	1173.0
05	1.0	7527.0	0.0	0.0
06	0.0	0.0	7528.0	0.0
07	6.0	0.0	7453.0	69.0
08	131.0	2386.0	1.0	5010.0
09	2090.0	1426.0	250.0	3762.0
10	5272.0	317.0	578.0	1361.0
11	3548.0	981.0	1430.0	1569.0

PFM

	A	C	G	T
01	0.264	0.159	0.155	0.422
02	0.286	0.139	0.149	0.426
03	0.443	0.005	0.171	0.38
04	0.442	0.176	0.226	0.156
05	0.0	1.0	0.0	0.0
06	0.0	0.0	1.0	0.0
07	0.001	0.0	0.99	0.009
08	0.017	0.317	0.0	0.666
09	0.278	0.189	0.033	0.5
10	0.7	0.042	0.077	0.181
11	0.471	0.13	0.19	0.208

PWM

	A	C	G	T
01	0.054	-0.452	-0.475	0.523
02	0.135	-0.586	-0.518	0.532
03	0.571	-3.775	-0.377	0.419
04	0.57	-0.352	-0.099	-0.472
05	-6.368	1.385	-6.739	-6.739
06	-6.739	-6.739	1.385	-6.739
07	-5.433	-6.739	1.375	-3.275
08	-2.649	0.237	-6.368	0.978
09	0.105	-0.277	-2.011	0.692
10	1.029	-1.775	-1.178	-0.324
11	0.633	-0.65	-0.274	-0.182

Standard thresholds

P-value	Threshold
0.001	5.379215
0.0005	6.102265
0.0001	7.3156