| Motif | SP1.H14RSNP.2.P.B |
| Gene (human) | SP1 (GeneCards) |
| Gene synonyms (human) | TSFP1 |
| Gene (mouse) | Sp1 |
| Gene synonyms (mouse) | |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 2 |
| Quality | B |
| Motif | SP1.H14RSNP.2.P.B |
| Gene (human) | SP1 (GeneCards) |
| Gene synonyms (human) | TSFP1 |
| Gene (mouse) | Sp1 |
| Gene synonyms (mouse) | |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 2 |
| Quality | B |
| Motif length | 23 |
| Consensus | SSSSSvRGGGGCGGGGCSdSSSS |
| GC content | 87.99% |
| Information content (bits; total / per base) | 24.061 / 1.046 |
| Data sources | ChIP-Seq |
| Aligned words | 999 |
| Previous names | SP1.H12RSNP.2.P.B |
| ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Human | 14 (91) | 0.841 | 0.958 | 0.677 | 0.903 | 0.919 | 0.993 | 4.432 | 7.15 | 56.959 | 216.081 |
| Mouse | 10 (52) | 0.856 | 0.917 | 0.745 | 0.817 | 0.842 | 0.92 | 3.812 | 4.337 | 46.19 | 106.553 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Overall, 3 experiments | median | 0.907 | 0.861 | 0.782 | 0.761 | 0.614 | 0.649 |
| best | 0.927 | 0.886 | 0.851 | 0.816 | 0.686 | 0.701 | |
| Methyl HT-SELEX, 1 experiments | median | 0.907 | 0.861 | 0.782 | 0.761 | 0.614 | 0.649 |
| best | 0.907 | 0.861 | 0.782 | 0.761 | 0.614 | 0.649 | |
| Non-Methyl HT-SELEX, 2 experiments | median | 0.89 | 0.847 | 0.771 | 0.752 | 0.63 | 0.653 |
| best | 0.927 | 0.886 | 0.851 | 0.816 | 0.686 | 0.701 | |
| rSNP benchmarking, ADASTRA | odds-ratio | -log-Fisher's P | Pearson r | Kendall tau |
|---|---|---|---|---|
| # | 1.842 | 2.562 | 0.022 | 0.013 |
| TF superclass | Zinc-coordinating DNA-binding domains {2} (TFClass) |
| TF class | C2H2 zinc finger factors {2.3} (TFClass) |
| TF family | Three-zinc finger Kruppel-related {2.3.1} (TFClass) |
| TF subfamily | Sp1-like {2.3.1.1} (TFClass) |
| TFClass ID | TFClass: 2.3.1.1.1 |
| HGNC | HGNC:11205 |
| MGI | MGI:98372 |
| EntrezGene (human) | GeneID:6667 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:20683 (SSTAR profile) |
| UniProt ID (human) | SP1_HUMAN |
| UniProt ID (mouse) | SP1_MOUSE |
| UniProt AC (human) | P08047 (TFClass) |
| UniProt AC (mouse) | O89090 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 14 human, 10 mouse |
| HT-SELEX | 2 |
| Methyl-HT-SELEX | 1 |
| Genomic HT-SELEX | 0 overall: 0 Lysate, 0 IVT, 0 GFPIVT |
| SMiLE-Seq | 0 |
| PBM | 0 |
| PCM | SP1.H14RSNP.2.P.B.pcm |
| PWM | SP1.H14RSNP.2.P.B.pwm |
| PFM | SP1.H14RSNP.2.P.B.pfm |
| Threshold to P-value map | SP1.H14RSNP.2.P.B.thr |
| Motif in other formats | |
| JASPAR format | SP1.H14RSNP.2.P.B_jaspar_format.txt |
| MEME format | SP1.H14RSNP.2.P.B_meme_format.meme |
| Transfac format | SP1.H14RSNP.2.P.B_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 75.0 | 369.0 | 507.0 | 48.0 |
| 02 | 97.0 | 282.0 | 556.0 | 64.0 |
| 03 | 101.0 | 169.0 | 650.0 | 79.0 |
| 04 | 53.0 | 207.0 | 678.0 | 61.0 |
| 05 | 101.0 | 262.0 | 568.0 | 68.0 |
| 06 | 319.0 | 289.0 | 295.0 | 96.0 |
| 07 | 187.0 | 162.0 | 629.0 | 21.0 |
| 08 | 21.0 | 2.0 | 870.0 | 106.0 |
| 09 | 26.0 | 0.0 | 973.0 | 0.0 |
| 10 | 0.0 | 0.0 | 999.0 | 0.0 |
| 11 | 0.0 | 4.0 | 992.0 | 3.0 |
| 12 | 23.0 | 972.0 | 0.0 | 4.0 |
| 13 | 0.0 | 1.0 | 997.0 | 1.0 |
| 14 | 3.0 | 0.0 | 948.0 | 48.0 |
| 15 | 24.0 | 0.0 | 971.0 | 4.0 |
| 16 | 12.0 | 22.0 | 952.0 | 13.0 |
| 17 | 36.0 | 924.0 | 19.0 | 20.0 |
| 18 | 35.0 | 621.0 | 230.0 | 113.0 |
| 19 | 130.0 | 117.0 | 501.0 | 251.0 |
| 20 | 106.0 | 182.0 | 674.0 | 37.0 |
| 21 | 83.0 | 201.0 | 704.0 | 11.0 |
| 22 | 110.0 | 258.0 | 590.0 | 41.0 |
| 23 | 54.0 | 339.0 | 532.0 | 74.0 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.075 | 0.369 | 0.508 | 0.048 |
| 02 | 0.097 | 0.282 | 0.557 | 0.064 |
| 03 | 0.101 | 0.169 | 0.651 | 0.079 |
| 04 | 0.053 | 0.207 | 0.679 | 0.061 |
| 05 | 0.101 | 0.262 | 0.569 | 0.068 |
| 06 | 0.319 | 0.289 | 0.295 | 0.096 |
| 07 | 0.187 | 0.162 | 0.63 | 0.021 |
| 08 | 0.021 | 0.002 | 0.871 | 0.106 |
| 09 | 0.026 | 0.0 | 0.974 | 0.0 |
| 10 | 0.0 | 0.0 | 1.0 | 0.0 |
| 11 | 0.0 | 0.004 | 0.993 | 0.003 |
| 12 | 0.023 | 0.973 | 0.0 | 0.004 |
| 13 | 0.0 | 0.001 | 0.998 | 0.001 |
| 14 | 0.003 | 0.0 | 0.949 | 0.048 |
| 15 | 0.024 | 0.0 | 0.972 | 0.004 |
| 16 | 0.012 | 0.022 | 0.953 | 0.013 |
| 17 | 0.036 | 0.925 | 0.019 | 0.02 |
| 18 | 0.035 | 0.622 | 0.23 | 0.113 |
| 19 | 0.13 | 0.117 | 0.502 | 0.251 |
| 20 | 0.106 | 0.182 | 0.675 | 0.037 |
| 21 | 0.083 | 0.201 | 0.705 | 0.011 |
| 22 | 0.11 | 0.258 | 0.591 | 0.041 |
| 23 | 0.054 | 0.339 | 0.533 | 0.074 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | -1.187 | 0.388 | 0.705 | -1.621 |
| 02 | -0.935 | 0.121 | 0.797 | -1.342 |
| 03 | -0.895 | -0.387 | 0.952 | -1.136 |
| 04 | -1.525 | -0.186 | 0.994 | -1.389 |
| 05 | -0.895 | 0.048 | 0.818 | -1.283 |
| 06 | 0.243 | 0.145 | 0.165 | -0.945 |
| 07 | -0.287 | -0.429 | 0.92 | -2.404 |
| 08 | -2.404 | -4.212 | 1.243 | -0.848 |
| 09 | -2.205 | -4.981 | 1.355 | -4.981 |
| 10 | -4.981 | -4.981 | 1.381 | -4.981 |
| 11 | -4.981 | -3.782 | 1.374 | -3.974 |
| 12 | -2.319 | 1.354 | -4.981 | -3.782 |
| 13 | -4.981 | -4.524 | 1.379 | -4.524 |
| 14 | -3.974 | -4.981 | 1.329 | -1.621 |
| 15 | -2.28 | -4.981 | 1.353 | -3.782 |
| 16 | -2.908 | -2.361 | 1.333 | -2.838 |
| 17 | -1.897 | 1.303 | -2.496 | -2.449 |
| 18 | -1.924 | 0.907 | -0.082 | -0.785 |
| 19 | -0.647 | -0.751 | 0.693 | 0.005 |
| 20 | -0.848 | -0.314 | 0.988 | -1.871 |
| 21 | -1.088 | -0.215 | 1.032 | -2.984 |
| 22 | -0.811 | 0.032 | 0.856 | -1.773 |
| 23 | -1.507 | 0.304 | 0.753 | -1.2 |
| P-value | Threshold |
|---|---|
| 0.001 | -2.77129 |
| 0.0005 | -1.07529 |
| 0.0001 | 2.52121 |