| Motif | SP1.H14INVITRO.2.P.B |
| Gene (human) | SP1 (GeneCards) |
| Gene synonyms (human) | TSFP1 |
| Gene (mouse) | Sp1 |
| Gene synonyms (mouse) | |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 2 |
| Quality | B |
| Motif | SP1.H14INVITRO.2.P.B |
| Gene (human) | SP1 (GeneCards) |
| Gene synonyms (human) | TSFP1 |
| Gene (mouse) | Sp1 |
| Gene synonyms (mouse) | |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 2 |
| Quality | B |
| Motif length | 21 |
| Consensus | vvndRKGGGCGGGGCYdvvvv |
| GC content | 74.43% |
| Information content (bits; total / per base) | 17.156 / 0.817 |
| Data sources | ChIP-Seq |
| Aligned words | 922 |
| Previous names | SP1.H12INVITRO.2.P.B |
| ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Human | 14 (91) | 0.862 | 0.965 | 0.716 | 0.911 | 0.94 | 0.992 | 4.619 | 6.441 | 64.824 | 176.292 |
| Mouse | 10 (52) | 0.88 | 0.946 | 0.78 | 0.873 | 0.894 | 0.96 | 4.175 | 4.72 | 51.301 | 144.119 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Overall, 3 experiments | median | 0.973 | 0.957 | 0.859 | 0.855 | 0.659 | 0.707 |
| best | 0.979 | 0.965 | 0.932 | 0.915 | 0.74 | 0.77 | |
| Methyl HT-SELEX, 1 experiments | median | 0.973 | 0.957 | 0.859 | 0.855 | 0.659 | 0.707 |
| best | 0.973 | 0.957 | 0.859 | 0.855 | 0.659 | 0.707 | |
| Non-Methyl HT-SELEX, 2 experiments | median | 0.96 | 0.94 | 0.851 | 0.846 | 0.672 | 0.711 |
| best | 0.979 | 0.965 | 0.932 | 0.915 | 0.74 | 0.77 | |
| rSNP benchmarking, ADASTRA | odds-ratio | -log-Fisher's P | Pearson r | Kendall tau |
|---|---|---|---|---|
| # | 1.256 | 0.557 | 0.025 | 0.011 |
| TF superclass | Zinc-coordinating DNA-binding domains {2} (TFClass) |
| TF class | C2H2 zinc finger factors {2.3} (TFClass) |
| TF family | Three-zinc finger Kruppel-related {2.3.1} (TFClass) |
| TF subfamily | Sp1-like {2.3.1.1} (TFClass) |
| TFClass ID | TFClass: 2.3.1.1.1 |
| HGNC | HGNC:11205 |
| MGI | MGI:98372 |
| EntrezGene (human) | GeneID:6667 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:20683 (SSTAR profile) |
| UniProt ID (human) | SP1_HUMAN |
| UniProt ID (mouse) | SP1_MOUSE |
| UniProt AC (human) | P08047 (TFClass) |
| UniProt AC (mouse) | O89090 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 14 human, 10 mouse |
| HT-SELEX | 2 |
| Methyl-HT-SELEX | 1 |
| Genomic HT-SELEX | 0 overall: 0 Lysate, 0 IVT, 0 GFPIVT |
| SMiLE-Seq | 0 |
| PBM | 0 |
| PCM | SP1.H14INVITRO.2.P.B.pcm |
| PWM | SP1.H14INVITRO.2.P.B.pwm |
| PFM | SP1.H14INVITRO.2.P.B.pfm |
| Threshold to P-value map | SP1.H14INVITRO.2.P.B.thr |
| Motif in other formats | |
| JASPAR format | SP1.H14INVITRO.2.P.B_jaspar_format.txt |
| MEME format | SP1.H14INVITRO.2.P.B_meme_format.meme |
| Transfac format | SP1.H14INVITRO.2.P.B_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 163.0 | 153.0 | 497.0 | 109.0 |
| 02 | 132.0 | 154.0 | 506.0 | 130.0 |
| 03 | 241.0 | 216.0 | 330.0 | 135.0 |
| 04 | 431.0 | 107.0 | 249.0 | 135.0 |
| 05 | 323.0 | 35.0 | 523.0 | 41.0 |
| 06 | 120.0 | 2.0 | 637.0 | 163.0 |
| 07 | 124.0 | 1.0 | 796.0 | 1.0 |
| 08 | 11.0 | 0.0 | 910.0 | 1.0 |
| 09 | 6.0 | 0.0 | 916.0 | 0.0 |
| 10 | 24.0 | 834.0 | 0.0 | 64.0 |
| 11 | 9.0 | 4.0 | 903.0 | 6.0 |
| 12 | 9.0 | 5.0 | 784.0 | 124.0 |
| 13 | 129.0 | 2.0 | 762.0 | 29.0 |
| 14 | 92.0 | 23.0 | 782.0 | 25.0 |
| 15 | 86.0 | 741.0 | 17.0 | 78.0 |
| 16 | 73.0 | 557.0 | 94.0 | 198.0 |
| 17 | 302.0 | 111.0 | 216.0 | 293.0 |
| 18 | 211.0 | 128.0 | 476.0 | 107.0 |
| 19 | 226.0 | 116.0 | 504.0 | 76.0 |
| 20 | 180.0 | 157.0 | 497.0 | 88.0 |
| 21 | 143.0 | 274.0 | 393.0 | 112.0 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.177 | 0.166 | 0.539 | 0.118 |
| 02 | 0.143 | 0.167 | 0.549 | 0.141 |
| 03 | 0.261 | 0.234 | 0.358 | 0.146 |
| 04 | 0.467 | 0.116 | 0.27 | 0.146 |
| 05 | 0.35 | 0.038 | 0.567 | 0.044 |
| 06 | 0.13 | 0.002 | 0.691 | 0.177 |
| 07 | 0.134 | 0.001 | 0.863 | 0.001 |
| 08 | 0.012 | 0.0 | 0.987 | 0.001 |
| 09 | 0.007 | 0.0 | 0.993 | 0.0 |
| 10 | 0.026 | 0.905 | 0.0 | 0.069 |
| 11 | 0.01 | 0.004 | 0.979 | 0.007 |
| 12 | 0.01 | 0.005 | 0.85 | 0.134 |
| 13 | 0.14 | 0.002 | 0.826 | 0.031 |
| 14 | 0.1 | 0.025 | 0.848 | 0.027 |
| 15 | 0.093 | 0.804 | 0.018 | 0.085 |
| 16 | 0.079 | 0.604 | 0.102 | 0.215 |
| 17 | 0.328 | 0.12 | 0.234 | 0.318 |
| 18 | 0.229 | 0.139 | 0.516 | 0.116 |
| 19 | 0.245 | 0.126 | 0.547 | 0.082 |
| 20 | 0.195 | 0.17 | 0.539 | 0.095 |
| 21 | 0.155 | 0.297 | 0.426 | 0.121 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | -0.343 | -0.406 | 0.764 | -0.741 |
| 02 | -0.552 | -0.4 | 0.782 | -0.567 |
| 03 | 0.044 | -0.064 | 0.357 | -0.53 |
| 04 | 0.622 | -0.759 | 0.077 | -0.53 |
| 05 | 0.335 | -1.845 | 0.815 | -1.693 |
| 06 | -0.646 | -4.138 | 1.012 | -0.343 |
| 07 | -0.614 | -4.452 | 1.234 | -4.452 |
| 08 | -2.906 | -4.913 | 1.368 | -4.452 |
| 09 | -3.406 | -4.913 | 1.374 | -4.913 |
| 10 | -2.201 | 1.281 | -4.913 | -1.262 |
| 11 | -3.077 | -3.706 | 1.36 | -3.406 |
| 12 | -3.077 | -3.545 | 1.219 | -0.614 |
| 13 | -0.575 | -4.138 | 1.191 | -2.023 |
| 14 | -0.907 | -2.241 | 1.216 | -2.163 |
| 15 | -0.974 | 1.163 | -2.519 | -1.069 |
| 16 | -1.134 | 0.878 | -0.886 | -0.151 |
| 17 | 0.268 | -0.723 | -0.064 | 0.238 |
| 18 | -0.088 | -0.582 | 0.721 | -0.759 |
| 19 | -0.02 | -0.679 | 0.778 | -1.095 |
| 20 | -0.245 | -0.381 | 0.764 | -0.951 |
| 21 | -0.473 | 0.172 | 0.531 | -0.714 |
| P-value | Threshold |
|---|---|
| 0.001 | 1.92776 |
| 0.0005 | 3.23856 |
| 0.0001 | 5.96766 |