| Motif | SIX6.H14INVIVO.0.SM.D |
| Gene (human) | SIX6 (GeneCards) |
| Gene synonyms (human) | OPTX2, SIX9 |
| Gene (mouse) | Six6 |
| Gene synonyms (mouse) | Optx2, Six9 |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 0 |
| Quality | D |
| Motif | SIX6.H14INVIVO.0.SM.D |
| Gene (human) | SIX6 (GeneCards) |
| Gene synonyms (human) | OPTX2, SIX9 |
| Gene (mouse) | Six6 |
| Gene synonyms (mouse) | Optx2, Six9 |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 0 |
| Quality | D |
| Motif length | 9 |
| Consensus | nYGATAYbn |
| GC content | 44.55% |
| Information content (bits; total / per base) | 8.528 / 0.948 |
| Data sources | HT-SELEX + Methyl-HT-SELEX |
| Aligned words | 9702 |
| Previous names | SIX6.H12INVIVO.0.SM.D |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Overall, 2 experiments | median | 0.876 | 0.821 | 0.814 | 0.764 | 0.723 | 0.695 |
| best | 0.891 | 0.841 | 0.831 | 0.782 | 0.745 | 0.713 | |
| Methyl HT-SELEX, 1 experiments | median | 0.861 | 0.801 | 0.797 | 0.745 | 0.701 | 0.676 |
| best | 0.861 | 0.801 | 0.797 | 0.745 | 0.701 | 0.676 | |
| Non-Methyl HT-SELEX, 1 experiments | median | 0.891 | 0.841 | 0.831 | 0.782 | 0.745 | 0.713 |
| best | 0.891 | 0.841 | 0.831 | 0.782 | 0.745 | 0.713 | |
| TF superclass | Helix-turn-helix domains {3} (TFClass) |
| TF class | Homeo domain factors {3.1} (TFClass) |
| TF family | HD-SINE {3.1.6} (TFClass) |
| TF subfamily | SIX3-like {3.1.6.2} (TFClass) |
| TFClass ID | TFClass: 3.1.6.2.2 |
| HGNC | HGNC:10892 |
| MGI | MGI:1341840 |
| EntrezGene (human) | GeneID:4990 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:20476 (SSTAR profile) |
| UniProt ID (human) | SIX6_HUMAN |
| UniProt ID (mouse) | SIX6_MOUSE |
| UniProt AC (human) | O95475 (TFClass) |
| UniProt AC (mouse) | Q9QZ28 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 0 human, 0 mouse |
| HT-SELEX | 1 |
| Methyl-HT-SELEX | 1 |
| Genomic HT-SELEX | 0 overall: 0 Lysate, 0 IVT, 0 GFPIVT |
| SMiLE-Seq | 0 |
| PBM | 0 |
| PCM | SIX6.H14INVIVO.0.SM.D.pcm |
| PWM | SIX6.H14INVIVO.0.SM.D.pwm |
| PFM | SIX6.H14INVIVO.0.SM.D.pfm |
| Threshold to P-value map | SIX6.H14INVIVO.0.SM.D.thr |
| Motif in other formats | |
| JASPAR format | SIX6.H14INVIVO.0.SM.D_jaspar_format.txt |
| MEME format | SIX6.H14INVIVO.0.SM.D_meme_format.meme |
| Transfac format | SIX6.H14INVIVO.0.SM.D_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 2827.75 | 1422.75 | 3287.75 | 2163.75 |
| 02 | 424.25 | 3144.25 | 879.25 | 5254.25 |
| 03 | 23.0 | 1.0 | 9669.0 | 9.0 |
| 04 | 9671.0 | 8.0 | 4.0 | 19.0 |
| 05 | 36.0 | 22.0 | 1.0 | 9643.0 |
| 06 | 8657.0 | 994.0 | 48.0 | 3.0 |
| 07 | 666.0 | 6020.0 | 1302.0 | 1714.0 |
| 08 | 1260.5 | 3744.5 | 3276.5 | 1420.5 |
| 09 | 2018.5 | 2690.5 | 2384.5 | 2608.5 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.291 | 0.147 | 0.339 | 0.223 |
| 02 | 0.044 | 0.324 | 0.091 | 0.542 |
| 03 | 0.002 | 0.0 | 0.997 | 0.001 |
| 04 | 0.997 | 0.001 | 0.0 | 0.002 |
| 05 | 0.004 | 0.002 | 0.0 | 0.994 |
| 06 | 0.892 | 0.102 | 0.005 | 0.0 |
| 07 | 0.069 | 0.62 | 0.134 | 0.177 |
| 08 | 0.13 | 0.386 | 0.338 | 0.146 |
| 09 | 0.208 | 0.277 | 0.246 | 0.269 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.153 | -0.533 | 0.304 | -0.114 |
| 02 | -1.739 | 0.259 | -1.013 | 0.772 |
| 03 | -4.564 | -6.602 | 1.382 | -5.37 |
| 04 | 1.382 | -5.463 | -5.955 | -4.736 |
| 05 | -4.149 | -4.604 | -6.602 | 1.379 |
| 06 | 1.272 | -0.891 | -3.877 | -6.128 |
| 07 | -1.29 | 0.908 | -0.621 | -0.347 |
| 08 | -0.654 | 0.434 | 0.3 | -0.534 |
| 09 | -0.183 | 0.104 | -0.017 | 0.073 |
| P-value | Threshold |
|---|---|
| 0.001 | 5.48069 |
| 0.0005 | 6.129505 |
| 0.0001 | 7.26429 |