MotifRFX1.H14INVITRO.1.PSM.A
Gene (human)RFX1
(GeneCards)
Gene synonyms (human)
Gene (mouse)Rfx1
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
A
Motif length17
ConsensusnbGTTRCCATGGCAACn
GC content52.1%
Information content (bits; total / per base)21.802 / 1.282
Data sourcesChIP-Seq + HT-SELEX + Methyl-HT-SELEX
Aligned words9999
Previous namesRFX1.H12INVITRO.1.PSM.A

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 5 (35) 0.924 0.964 0.904 0.958 0.906 0.955 6.434 8.791 599.377 881.523
Mouse 4 (20) 0.918 0.943 0.894 0.926 0.906 0.937 6.132 7.331 568.569 781.347

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.999 0.999 0.964 0.964 0.877 0.888
best 1 1 1.0 1.0 0.991 0.991
Methyl HT-SELEX, 2 experiments median 0.999 0.999 0.964 0.964 0.877 0.888
best 1 1 1.0 1.0 0.989 0.989
Non-Methyl HT-SELEX, 2 experiments median 0.874 0.869 0.82 0.819 0.785 0.788
best 1 1 1.0 1.0 0.991 0.991

rSNP benchmarking, ADASTRA odds-ratio -log-Fisher's P Pearson r Kendall tau
# 2.561 7.553 0.206 0.089

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 1 0.901 0.622 0.917 0.596
batch 2 0.905 0.846 0.846 0.493
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classFork head/winged helix factors {3.3} (TFClass)
TF familyRFX {3.3.3} (TFClass)
TF subfamily {3.3.3.0} (TFClass)
TFClass IDTFClass: 3.3.3.0.1
HGNCHGNC:9982
MGIMGI:105982
EntrezGene (human)GeneID:5989
(SSTAR profile)
EntrezGene (mouse)GeneID:19724
(SSTAR profile)
UniProt ID (human)RFX1_HUMAN
UniProt ID (mouse)RFX1_MOUSE
UniProt AC (human)P22670
(TFClass)
UniProt AC (mouse)P48377
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 5 human, 4 mouse
HT-SELEX 2
Methyl-HT-SELEX 2
Genomic HT-SELEX 0 overall: 0 Lysate, 0 IVT, 0 GFPIVT
SMiLE-Seq 0
PBM 0
PCM
ACGT
011882.02930.01785.03402.0
02932.255014.252781.251271.25
0350.07.09936.06.0
0428.056.08.09907.0
052259.077.03.07660.0
065381.01.04298.0319.0
070.09774.05.0220.0
083.09589.00.0407.0
099861.04.0106.028.0
1045.055.018.09881.0
111294.013.08675.017.0
122233.041.07717.08.0
13296.08424.080.01199.0
147873.056.01858.0212.0
159819.064.057.059.0
16156.58925.591.5825.5
172431.752586.753523.751456.75
PFM
ACGT
010.1880.2930.1790.34
020.0930.5010.2780.127
030.0050.0010.9940.001
040.0030.0060.0010.991
050.2260.0080.00.766
060.5380.00.430.032
070.00.9770.0010.022
080.00.9590.00.041
090.9860.00.0110.003
100.0050.0060.0020.988
110.1290.0010.8680.002
120.2230.0040.7720.001
130.030.8420.0080.12
140.7870.0060.1860.021
150.9820.0060.0060.006
160.0160.8930.0090.083
170.2430.2590.3520.146
PWM
ACGT
01-0.2840.159-0.3360.308
02-0.9850.6960.107-0.675
03-3.868-5.5951.379-5.708
04-4.414-3.759-5.4921.376
05-0.101-3.452-6.1571.119
060.766-6.630.542-2.052
07-6.9911.363-5.837-2.421
08-6.1571.344-6.991-1.81
091.372-5.984-3.14-4.414
10-3.968-3.777-4.8141.374
11-0.658-5.0971.244-4.865
12-0.113-4.0571.127-5.492
13-2.1271.214-3.414-0.734
141.147-3.759-0.296-2.457
151.367-3.631-3.742-3.709
16-2.7571.272-3.284-1.106
17-0.0280.0340.343-0.539
Standard thresholds
P-value Threshold
0.001 -3.59529
0.0005 -1.71064
0.0001 2.25601