REST.H14CORE.0.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	REST.H14CORE.0.P.B
Gene (human)	REST (GeneCards)
Gene synonyms (human)	NRSF, XBR
Gene (mouse)	Rest
Gene synonyms (mouse)	Nrsf
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	22
Consensus	bbYRSnMCShhGGACAGMdSMh
GC content	60.88%
Information content (bits; total / per base)	18.577 / 0.844
Data sources	ChIP-Seq
Aligned words	717
Previous names	REST.H12CORE.0.P.B

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	63 (418)	0.975	0.993	0.966	0.989	0.971	0.993	10.266	12.079	662.495	1089.244
Mouse	25 (165)	0.98	0.992	0.967	0.984	0.976	0.99	10.071	10.815	597.208	810.469

rSNP benchmarking, ADASTRA	odds-ratio	-log-Fisher's P	Pearson r	Kendall tau
#	4.238	9.02	0.136	0.056

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	Multiple dispersed zinc fingers {2.3.4} (TFClass)
TF subfamily	Unclassified {2.3.4.0} (TFClass)
TFClass ID	TFClass: 2.3.4.0.27
HGNC	HGNC:9966
MGI	MGI:104897
EntrezGene (human)	GeneID:5978 (SSTAR profile)
EntrezGene (mouse)	GeneID:19712 (SSTAR profile)
UniProt ID (human)	REST_HUMAN
UniProt ID (mouse)	REST_MOUSE
UniProt AC (human)	Q13127 (TFClass)
UniProt AC (mouse)	Q8VIG1 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	63 human, 25 mouse
HT-SELEX	0
Methyl-HT-SELEX	0
Genomic HT-SELEX	0 overall: 0 Lysate, 0 IVT, 0 GFPIVT
SMiLE-Seq	0
PBM	0

PCM	REST.H14CORE.0.P.B.pcm
PWM	REST.H14CORE.0.P.B.pwm
PFM	REST.H14CORE.0.P.B.pfm
Threshold to P-value map	REST.H14CORE.0.P.B.thr
Motif in other formats
JASPAR format	REST.H14CORE.0.P.B_jaspar_format.txt
MEME format	REST.H14CORE.0.P.B_meme_format.meme
Transfac format	REST.H14CORE.0.P.B_transfac_format.txt
Homer format	REST.H14CORE.0.P.B_homer_format_0.001.txt REST.H14CORE.0.P.B_homer_format_0.0005.txt REST.H14CORE.0.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	111.0	145.0	177.0	284.0
02	53.0	207.0	78.0	379.0
03	61.0	499.0	53.0	104.0
04	508.0	60.0	109.0	40.0
05	62.0	89.0	534.0	32.0
06	82.0	395.0	158.0	82.0
07	562.0	54.0	50.0	51.0
08	31.0	595.0	45.0	46.0
09	46.0	541.0	90.0	40.0
10	358.0	122.0	107.0	130.0
11	94.0	178.0	63.0	382.0
12	14.0	9.0	683.0	11.0
13	10.0	14.0	680.0	13.0
14	635.0	40.0	12.0	30.0
15	7.0	626.0	67.0	17.0
16	699.0	5.0	8.0	5.0
17	6.0	5.0	703.0	3.0
18	89.0	533.0	30.0	65.0
19	185.0	10.0	293.0	229.0
20	94.0	452.0	137.0	34.0
21	74.0	560.0	18.0	65.0
22	180.0	286.0	83.0	168.0

PFM

	A	C	G	T
01	0.155	0.202	0.247	0.396
02	0.074	0.289	0.109	0.529
03	0.085	0.696	0.074	0.145
04	0.709	0.084	0.152	0.056
05	0.086	0.124	0.745	0.045
06	0.114	0.551	0.22	0.114
07	0.784	0.075	0.07	0.071
08	0.043	0.83	0.063	0.064
09	0.064	0.755	0.126	0.056
10	0.499	0.17	0.149	0.181
11	0.131	0.248	0.088	0.533
12	0.02	0.013	0.953	0.015
13	0.014	0.02	0.948	0.018
14	0.886	0.056	0.017	0.042
15	0.01	0.873	0.093	0.024
16	0.975	0.007	0.011	0.007
17	0.008	0.007	0.98	0.004
18	0.124	0.743	0.042	0.091
19	0.258	0.014	0.409	0.319
20	0.131	0.63	0.191	0.047
21	0.103	0.781	0.025	0.091
22	0.251	0.399	0.116	0.234

PWM

	A	C	G	T
01	-0.474	-0.21	-0.013	0.457
02	-1.197	0.143	-0.82	0.744
03	-1.06	1.018	-1.197	-0.538
04	1.036	-1.077	-0.492	-1.469
05	-1.045	-0.691	1.086	-1.682
06	-0.771	0.785	-0.125	-0.771
07	1.137	-1.179	-1.254	-1.234
08	-1.712	1.193	-1.355	-1.334
09	-1.334	1.099	-0.68	-1.469
10	0.687	-0.381	-0.51	-0.318
11	-0.637	-0.007	-1.029	0.752
12	-2.448	-2.833	1.331	-2.661
13	-2.743	-2.448	1.327	-2.514
14	1.258	-1.469	-2.585	-1.743
15	-3.041	1.244	-0.969	-2.272
16	1.354	-3.304	-2.932	-3.304
17	-3.164	-3.304	1.36	-3.662
18	-0.691	1.084	-1.743	-0.999
19	0.031	-2.743	0.488	0.243
20	-0.637	0.919	-0.266	-1.624
21	-0.872	1.133	-2.22	-0.999
22	0.004	0.464	-0.759	-0.064

Standard thresholds

P-value	Threshold
0.001	1.95051
0.0005	3.15416
0.0001	5.71341