| Motif | PTF1A.H14INVIVO.1.PS.A |
| Gene (human) | PTF1A (GeneCards) |
| Gene synonyms (human) | BHLHA29, PTF1P48 |
| Gene (mouse) | Ptf1a |
| Gene synonyms (mouse) | Ptf1p48 |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 1 |
| Quality | A |
| Motif | PTF1A.H14INVIVO.1.PS.A |
| Gene (human) | PTF1A (GeneCards) |
| Gene synonyms (human) | BHLHA29, PTF1P48 |
| Gene (mouse) | Ptf1a |
| Gene synonyms (mouse) | Ptf1p48 |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 1 |
| Quality | A |
| Motif length | 8 |
| Consensus | CASCTGbb |
| GC content | 59.75% |
| Information content (bits; total / per base) | 9.06 / 1.132 |
| Data sources | ChIP-Seq + HT-SELEX |
| Aligned words | 996 |
| Previous names | PTF1A.H12INVIVO.1.PS.A |
| ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Mouse | 8 (52) | 0.871 | 0.913 | 0.779 | 0.828 | 0.785 | 0.838 | 2.052 | 2.242 | 205.905 | 319.268 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Non-Methyl HT-SELEX, 1 experiments | median | 0.942 | 0.921 | 0.831 | 0.815 | 0.704 | 0.709 |
| best | 0.942 | 0.921 | 0.831 | 0.815 | 0.704 | 0.709 | |
| TF superclass | Basic domains {1} (TFClass) |
| TF class | Basic helix-loop-helix factors (bHLH) {1.2} (TFClass) |
| TF family | Tal-related {1.2.3} (TFClass) |
| TF subfamily | TWIST {1.2.3.2} (TFClass) |
| TFClass ID | TFClass: 1.2.3.2.7 |
| HGNC | HGNC:23734 |
| MGI | MGI:1328312 |
| EntrezGene (human) | GeneID:256297 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:19213 (SSTAR profile) |
| UniProt ID (human) | PTF1A_HUMAN |
| UniProt ID (mouse) | PTF1A_MOUSE |
| UniProt AC (human) | Q7RTS3 (TFClass) |
| UniProt AC (mouse) | Q9QX98 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 0 human, 8 mouse |
| HT-SELEX | 1 |
| Methyl-HT-SELEX | 0 |
| Genomic HT-SELEX | 0 overall: 0 Lysate, 0 IVT, 0 GFPIVT |
| SMiLE-Seq | 0 |
| PBM | 0 |
| PCM | PTF1A.H14INVIVO.1.PS.A.pcm |
| PWM | PTF1A.H14INVIVO.1.PS.A.pwm |
| PFM | PTF1A.H14INVIVO.1.PS.A.pfm |
| Threshold to P-value map | PTF1A.H14INVIVO.1.PS.A.thr |
| Motif in other formats | |
| JASPAR format | PTF1A.H14INVIVO.1.PS.A_jaspar_format.txt |
| MEME format | PTF1A.H14INVIVO.1.PS.A_meme_format.meme |
| Transfac format | PTF1A.H14INVIVO.1.PS.A_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 62.0 | 888.0 | 29.0 | 17.0 |
| 02 | 910.0 | 33.0 | 10.0 | 43.0 |
| 03 | 29.0 | 421.0 | 424.0 | 122.0 |
| 04 | 31.0 | 955.0 | 4.0 | 6.0 |
| 05 | 10.0 | 1.0 | 1.0 | 984.0 |
| 06 | 3.0 | 4.0 | 976.0 | 13.0 |
| 07 | 43.0 | 262.0 | 257.0 | 434.0 |
| 08 | 128.0 | 190.0 | 306.0 | 372.0 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.062 | 0.892 | 0.029 | 0.017 |
| 02 | 0.914 | 0.033 | 0.01 | 0.043 |
| 03 | 0.029 | 0.423 | 0.426 | 0.122 |
| 04 | 0.031 | 0.959 | 0.004 | 0.006 |
| 05 | 0.01 | 0.001 | 0.001 | 0.988 |
| 06 | 0.003 | 0.004 | 0.98 | 0.013 |
| 07 | 0.043 | 0.263 | 0.258 | 0.436 |
| 08 | 0.129 | 0.191 | 0.307 | 0.373 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | -1.37 | 1.267 | -2.099 | -2.594 |
| 02 | 1.291 | -1.977 | -3.063 | -1.724 |
| 03 | -2.099 | 0.522 | 0.529 | -0.706 |
| 04 | -2.036 | 1.339 | -3.779 | -3.48 |
| 05 | -3.063 | -4.522 | -4.522 | 1.369 |
| 06 | -3.971 | -3.779 | 1.361 | -2.835 |
| 07 | -1.724 | 0.051 | 0.031 | 0.553 |
| 08 | -0.659 | -0.268 | 0.205 | 0.399 |
| P-value | Threshold |
|---|---|
| 0.001 | 4.771355 |
| 0.0005 | 5.820365 |
| 0.0001 | 7.584405 |