| Motif | PRDM5.H14INVIVO.0.PSGI.A |
| Gene (human) | PRDM5 (GeneCards) |
| Gene synonyms (human) | PFM2 |
| Gene (mouse) | Prdm5 |
| Gene synonyms (mouse) | |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 0 |
| Quality | A |
| Motif | PRDM5.H14INVIVO.0.PSGI.A |
| Gene (human) | PRDM5 (GeneCards) |
| Gene synonyms (human) | PFM2 |
| Gene (mouse) | Prdm5 |
| Gene synonyms (mouse) | |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 0 |
| Quality | A |
| Motif length | 16 |
| Consensus | vMCYbRnbCWCCdbbb |
| GC content | 65.01% |
| Information content (bits; total / per base) | 11.942 / 0.746 |
| Data sources | ChIP-Seq + HT-SELEX + Genomic HT-SELEX + SMiLe-Seq |
| Aligned words | 1000 |
| Previous names |
| ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | Centrality, median | Centrality, best |
|---|---|---|---|---|---|---|---|---|---|
| Overall | 3 (5) | 0.808 | 0.839 | 0.659 | 0.703 | 0.825 | 0.856 | 160.481 | 228.495 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| overall, 4 experiments | median | 0.958 | 0.941 | 0.902 | 0.886 | 0.823 | 0.821 |
| best | 0.995 | 0.991 | 0.99 | 0.985 | 0.977 | 0.968 | |
| Lysate, 2 experiments | median | 0.898 | 0.865 | 0.789 | 0.764 | 0.663 | 0.67 |
| best | 0.924 | 0.895 | 0.819 | 0.795 | 0.682 | 0.691 | |
| GFPIVT, 2 experiments | median | 0.994 | 0.989 | 0.988 | 0.981 | 0.97 | 0.959 |
| best | 0.995 | 0.991 | 0.99 | 0.985 | 0.977 | 0.968 | |
| Genomic HT-SELEX benchmarking | Centrality | pseudo-auROC | auROC | auPR | |
|---|---|---|---|---|---|
| overall, 4 experiments | median | 235.748 | 0.838 | 0.839 | 0.706 |
| best | 405.097 | 0.87 | 0.854 | 0.74 | |
| Lysate, 2 experiments | median | 222.921 | 0.792 | 0.779 | 0.642 |
| best | 288.796 | 0.831 | 0.834 | 0.698 | |
| GFPIVT, 2 experiments | median | 244.81 | 0.847 | 0.845 | 0.72 |
| best | 405.097 | 0.87 | 0.854 | 0.74 | |
| SMiLE-Seq benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Overall, 2 experiments | median | 0.821 | 0.801 | 0.718 | 0.709 | 0.628 | 0.637 |
| best | 0.92 | 0.888 | 0.836 | 0.804 | 0.721 | 0.712 | |
| TF superclass | Zinc-coordinating DNA-binding domains {2} (TFClass) |
| TF class | C2H2 zinc finger factors {2.3} (TFClass) |
| TF family | More than 3 adjacent zinc fingers {2.3.3} (TFClass) |
| TF subfamily | Unclassified {2.3.3.0} (TFClass) |
| TFClass ID | TFClass: 2.3.3.0.195 |
| HGNC | HGNC:9349 |
| MGI | MGI:1918029 |
| EntrezGene (human) | GeneID:11107 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:70779 (SSTAR profile) |
| UniProt ID (human) | PRDM5_HUMAN |
| UniProt ID (mouse) | PRDM5_MOUSE |
| UniProt AC (human) | Q9NQX1 (TFClass) |
| UniProt AC (mouse) | Q9CXE0 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 3 human, 0 mouse |
| HT-SELEX | 4 overall: 2 Lysate, 0 IVT, 2 GFPIVT |
| Genomic HT-SELEX | 4 overall: 2 Lysate, 0 IVT, 2 GFPIVT |
| SMiLE-Seq | 2 |
| PBM | 0 |
| PCM | PRDM5.H14INVIVO.0.PSGI.A.pcm |
| PWM | PRDM5.H14INVIVO.0.PSGI.A.pwm |
| PFM | PRDM5.H14INVIVO.0.PSGI.A.pfm |
| Threshold to P-value map | PRDM5.H14INVIVO.0.PSGI.A.thr |
| Motif in other formats | |
| JASPAR format | PRDM5.H14INVIVO.0.PSGI.A_jaspar_format.txt |
| MEME format | PRDM5.H14INVIVO.0.PSGI.A_meme_format.meme |
| Transfac format | PRDM5.H14INVIVO.0.PSGI.A_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 488.0 | 165.0 | 219.0 | 128.0 |
| 02 | 246.0 | 690.0 | 53.0 | 11.0 |
| 03 | 5.0 | 986.0 | 1.0 | 8.0 |
| 04 | 106.0 | 571.0 | 45.0 | 278.0 |
| 05 | 32.0 | 258.0 | 287.0 | 423.0 |
| 06 | 148.0 | 71.0 | 701.0 | 80.0 |
| 07 | 357.0 | 303.0 | 157.0 | 183.0 |
| 08 | 18.0 | 376.0 | 170.0 | 436.0 |
| 09 | 17.0 | 932.0 | 1.0 | 50.0 |
| 10 | 181.0 | 108.0 | 10.0 | 701.0 |
| 11 | 2.0 | 995.0 | 3.0 | 0.0 |
| 12 | 2.0 | 997.0 | 1.0 | 0.0 |
| 13 | 388.0 | 148.0 | 264.0 | 200.0 |
| 14 | 9.0 | 303.0 | 351.0 | 337.0 |
| 15 | 67.0 | 431.0 | 235.0 | 267.0 |
| 16 | 125.0 | 405.0 | 164.0 | 306.0 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.488 | 0.165 | 0.219 | 0.128 |
| 02 | 0.246 | 0.69 | 0.053 | 0.011 |
| 03 | 0.005 | 0.986 | 0.001 | 0.008 |
| 04 | 0.106 | 0.571 | 0.045 | 0.278 |
| 05 | 0.032 | 0.258 | 0.287 | 0.423 |
| 06 | 0.148 | 0.071 | 0.701 | 0.08 |
| 07 | 0.357 | 0.303 | 0.157 | 0.183 |
| 08 | 0.018 | 0.376 | 0.17 | 0.436 |
| 09 | 0.017 | 0.932 | 0.001 | 0.05 |
| 10 | 0.181 | 0.108 | 0.01 | 0.701 |
| 11 | 0.002 | 0.995 | 0.003 | 0.0 |
| 12 | 0.002 | 0.997 | 0.001 | 0.0 |
| 13 | 0.388 | 0.148 | 0.264 | 0.2 |
| 14 | 0.009 | 0.303 | 0.351 | 0.337 |
| 15 | 0.067 | 0.431 | 0.235 | 0.267 |
| 16 | 0.125 | 0.405 | 0.164 | 0.306 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.666 | -0.412 | -0.131 | -0.663 |
| 02 | -0.016 | 1.011 | -1.526 | -2.985 |
| 03 | -3.622 | 1.367 | -4.525 | -3.253 |
| 04 | -0.849 | 0.822 | -1.684 | 0.105 |
| 05 | -2.01 | 0.031 | 0.137 | 0.523 |
| 06 | -0.52 | -1.242 | 1.027 | -1.125 |
| 07 | 0.354 | 0.191 | -0.461 | -0.309 |
| 08 | -2.546 | 0.406 | -0.382 | 0.553 |
| 09 | -2.598 | 1.311 | -4.525 | -1.582 |
| 10 | -0.32 | -0.83 | -3.066 | 1.027 |
| 11 | -4.213 | 1.376 | -3.975 | -4.982 |
| 12 | -4.213 | 1.378 | -4.525 | -4.982 |
| 13 | 0.437 | -0.52 | 0.054 | -0.221 |
| 14 | -3.156 | 0.191 | 0.337 | 0.297 |
| 15 | -1.298 | 0.542 | -0.061 | 0.065 |
| 16 | -0.686 | 0.48 | -0.418 | 0.201 |
| P-value | Threshold |
|---|---|
| 0.001 | 4.11431 |
| 0.0005 | 5.22526 |
| 0.0001 | 7.36951 |