PO3F3.H14RSNP.1.P.D motif - HOmo sapiens COmprehensive MOdel COllection

Motif	PO3F3.H14RSNP.1.P.D
Gene (human)	POU3F3 (GeneCards)
Gene synonyms (human)	BRN1, OTF8
Gene (mouse)	Pou3f3
Gene synonyms (mouse)	Brn-1, Brn1, Otf8
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	D

Motif length	18
Consensus	bhbWTGMATWWKnMWdvv
GC content	34.78%
Information content (bits; total / per base)	11.528 / 0.64
Data sources	ChIP-Seq
Aligned words	1039
Previous names	PO3F3.H12RSNP.1.P.D

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Mouse	1 (7)	0.804	0.814	0.74	0.759	0.819	0.831	4.03	4.187	239.658	246.357

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 2 experiments	median	0.753	0.715	0.663	0.642	0.591	0.591
Non-Methyl HT-SELEX, 2 experiments	best	0.839	0.802	0.725	0.703	0.625	0.628

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Homeo domain factors {3.1} (TFClass)
TF family	POU {3.1.10} (TFClass)
TF subfamily	POU3 {3.1.10.3} (TFClass)
TFClass ID	TFClass: 3.1.10.3.3
HGNC	HGNC:9216
MGI	MGI:102564
EntrezGene (human)	GeneID:5455 (SSTAR profile)
EntrezGene (mouse)	GeneID:18993 (SSTAR profile)
UniProt ID (human)	PO3F3_HUMAN
UniProt ID (mouse)	PO3F3_MOUSE
UniProt AC (human)	P20264 (TFClass)
UniProt AC (mouse)	P31361 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 1 mouse
HT-SELEX	2
Methyl-HT-SELEX	0
Genomic HT-SELEX	0 overall: 0 Lysate, 0 IVT, 0 GFPIVT
SMiLE-Seq	0
PBM	0

PCM	PO3F3.H14RSNP.1.P.D.pcm
PWM	PO3F3.H14RSNP.1.P.D.pwm
PFM	PO3F3.H14RSNP.1.P.D.pfm
Threshold to P-value map	PO3F3.H14RSNP.1.P.D.thr
Motif in other formats
JASPAR format	PO3F3.H14RSNP.1.P.D_jaspar_format.txt
MEME format	PO3F3.H14RSNP.1.P.D_meme_format.meme
Transfac format	PO3F3.H14RSNP.1.P.D_transfac_format.txt
Homer format	PO3F3.H14RSNP.1.P.D_homer_format_0.001.txt PO3F3.H14RSNP.1.P.D_homer_format_0.0005.txt PO3F3.H14RSNP.1.P.D_homer_format_0.0001.txt

PCM

	A	C	G	T
01	134.0	450.0	299.0	156.0
02	380.0	132.0	100.0	427.0
03	69.0	488.0	111.0	371.0
04	576.0	153.0	31.0	279.0
05	63.0	7.0	32.0	937.0
06	40.0	29.0	956.0	14.0
07	408.0	614.0	6.0	11.0
08	1004.0	13.0	6.0	16.0
09	98.0	11.0	18.0	912.0
10	746.0	44.0	111.0	138.0
11	331.0	116.0	33.0	559.0
12	142.0	98.0	152.0	647.0
13	292.0	330.0	184.0	233.0
14	742.0	193.0	43.0	61.0
15	396.0	37.0	97.0	509.0
16	144.0	100.0	442.0	353.0
17	396.0	181.0	328.0	134.0
18	361.0	208.0	352.0	118.0

PFM

	A	C	G	T
01	0.129	0.433	0.288	0.15
02	0.366	0.127	0.096	0.411
03	0.066	0.47	0.107	0.357
04	0.554	0.147	0.03	0.269
05	0.061	0.007	0.031	0.902
06	0.038	0.028	0.92	0.013
07	0.393	0.591	0.006	0.011
08	0.966	0.013	0.006	0.015
09	0.094	0.011	0.017	0.878
10	0.718	0.042	0.107	0.133
11	0.319	0.112	0.032	0.538
12	0.137	0.094	0.146	0.623
13	0.281	0.318	0.177	0.224
14	0.714	0.186	0.041	0.059
15	0.381	0.036	0.093	0.49
16	0.139	0.096	0.425	0.34
17	0.381	0.174	0.316	0.129
18	0.347	0.2	0.339	0.114

PWM

	A	C	G	T
01	-0.656	0.547	0.14	-0.505
02	0.378	-0.671	-0.944	0.494
03	-1.307	0.627	-0.841	0.354
04	0.793	-0.525	-2.078	0.071
05	-1.396	-3.399	-2.048	1.278
06	-1.835	-2.141	1.298	-2.81
07	0.449	0.856	-3.52	-3.022
08	1.347	-2.876	-3.52	-2.691
09	-0.964	-3.022	-2.584	1.251
10	1.051	-1.743	-0.841	-0.627
11	0.241	-0.798	-2.019	0.763
12	-0.598	-0.964	-0.531	0.909
13	0.116	0.238	-0.342	-0.108
14	1.045	-0.295	-1.766	-1.427
15	0.419	-1.91	-0.974	0.669
16	-0.585	-0.944	0.529	0.305
17	0.419	-0.358	0.232	-0.656
18	0.327	-0.221	0.302	-0.781

Standard thresholds

P-value	Threshold
0.001	4.35466
0.0005	5.27201
0.0001	7.16796