PO3F3.H14INVITRO.2.S.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	PO3F3.H14INVITRO.2.S.B
Gene (human)	POU3F3 (GeneCards)
Gene synonyms (human)	BRN1, OTF8
Gene (mouse)	Pou3f3
Gene synonyms (mouse)	Brn-1, Brn1, Otf8
LOGO
LOGO (reverse complement)
Motif subtype	2
Quality	B

Motif length	12
Consensus	dnvhTAATTWvn
GC content	23.63%
Information content (bits; total / per base)	10.517 / 0.876
Data sources	HT-SELEX
Aligned words	9425
Previous names	PO3F3.H12INVITRO.2.S.B

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Mouse	1 (7)	0.644	0.656	0.453	0.461	0.673	0.685	1.935	1.968	44.658	49.097

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 2 experiments	median	0.778	0.723	0.702	0.667	0.626	0.614
Non-Methyl HT-SELEX, 2 experiments	best	0.871	0.811	0.79	0.745	0.68	0.667

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Homeo domain factors {3.1} (TFClass)
TF family	POU {3.1.10} (TFClass)
TF subfamily	POU3 {3.1.10.3} (TFClass)
TFClass ID	TFClass: 3.1.10.3.3
HGNC	HGNC:9216
MGI	MGI:102564
EntrezGene (human)	GeneID:5455 (SSTAR profile)
EntrezGene (mouse)	GeneID:18993 (SSTAR profile)
UniProt ID (human)	PO3F3_HUMAN
UniProt ID (mouse)	PO3F3_MOUSE
UniProt AC (human)	P20264 (TFClass)
UniProt AC (mouse)	P31361 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 1 mouse
HT-SELEX	2
Methyl-HT-SELEX	0
Genomic HT-SELEX	0 overall: 0 Lysate, 0 IVT, 0 GFPIVT
SMiLE-Seq	0
PBM	0

PCM	PO3F3.H14INVITRO.2.S.B.pcm
PWM	PO3F3.H14INVITRO.2.S.B.pwm
PFM	PO3F3.H14INVITRO.2.S.B.pfm
Threshold to P-value map	PO3F3.H14INVITRO.2.S.B.thr
Motif in other formats
JASPAR format	PO3F3.H14INVITRO.2.S.B_jaspar_format.txt
MEME format	PO3F3.H14INVITRO.2.S.B_meme_format.meme
Transfac format	PO3F3.H14INVITRO.2.S.B_transfac_format.txt
Homer format	PO3F3.H14INVITRO.2.S.B_homer_format_0.001.txt PO3F3.H14INVITRO.2.S.B_homer_format_0.0005.txt PO3F3.H14INVITRO.2.S.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	2413.0	1422.0	1541.0	4049.0
02	1754.25	1481.25	3118.25	3071.25
03	3526.0	2903.0	2388.0	608.0
04	2885.0	2735.0	646.0	3159.0
05	3.0	0.0	3.0	9419.0
06	9352.0	73.0	0.0	0.0
07	9420.0	3.0	2.0	0.0
08	3.0	9.0	14.0	9399.0
09	57.0	226.0	2056.0	7086.0
10	5896.0	1375.0	187.0	1967.0
11	5433.75	1245.75	1914.75	830.75
12	2867.0	1803.0	1578.0	3177.0

PFM

	A	C	G	T
01	0.256	0.151	0.164	0.43
02	0.186	0.157	0.331	0.326
03	0.374	0.308	0.253	0.065
04	0.306	0.29	0.069	0.335
05	0.0	0.0	0.0	0.999
06	0.992	0.008	0.0	0.0
07	0.999	0.0	0.0	0.0
08	0.0	0.001	0.001	0.997
09	0.006	0.024	0.218	0.752
10	0.626	0.146	0.02	0.209
11	0.577	0.132	0.203	0.088
12	0.304	0.191	0.167	0.337

PWM

	A	C	G	T
01	0.024	-0.504	-0.424	0.541
02	-0.295	-0.464	0.28	0.265
03	0.403	0.208	0.013	-1.352
04	0.202	0.149	-1.291	0.293
05	-6.1	-6.938	-6.1	1.385
06	1.378	-3.444	-6.938	-6.938
07	1.385	-6.1	-6.31	-6.938
08	-6.1	-5.342	-4.975	1.383
09	-3.683	-2.335	-0.136	1.1
10	0.917	-0.538	-2.523	-0.18
11	0.835	-0.636	-0.207	-1.041
12	0.196	-0.267	-0.4	0.299

Standard thresholds

P-value	Threshold
0.001	4.78892
0.0005	5.984025
0.0001	7.64645