PO3F1.H14INVIVO.2.S.C motif - HOmo sapiens COmprehensive MOdel COllection

Motif	PO3F1.H14INVIVO.2.S.C
Gene (human)	POU3F1 (GeneCards)
Gene synonyms (human)	OCT6, OTF6
Gene (mouse)	Pou3f1
Gene synonyms (mouse)	Oct6, Otf-6, Otf6, Scip
LOGO
LOGO (reverse complement)
Motif subtype	2
Quality	C

Motif length	9
Consensus	nTAATTMvn
GC content	26.55%
Information content (bits; total / per base)	9.362 / 1.04
Data sources	HT-SELEX
Aligned words	9399
Previous names	PO3F1.H12INVIVO.2.S.C

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Mouse	6 (39)	0.623	0.808	0.444	0.656	0.482	0.725	1.031	1.836	6.201	30.62

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 4 experiments	median	0.95	0.927	0.917	0.886	0.876	0.839
Overall, 4 experiments	best	0.981	0.97	0.942	0.917	0.912	0.877
Methyl HT-SELEX, 1 experiments	median	0.965	0.945	0.942	0.914	0.912	0.877
Methyl HT-SELEX, 1 experiments	best	0.965	0.945	0.942	0.914	0.912	0.877
Non-Methyl HT-SELEX, 3 experiments	median	0.934	0.909	0.896	0.858	0.855	0.811
Non-Methyl HT-SELEX, 3 experiments	best	0.981	0.97	0.938	0.917	0.897	0.867

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Homeo domain factors {3.1} (TFClass)
TF family	POU {3.1.10} (TFClass)
TF subfamily	POU3 {3.1.10.3} (TFClass)
TFClass ID	TFClass: 3.1.10.3.1
HGNC	HGNC:9214
MGI	MGI:101896
EntrezGene (human)	GeneID:5453 (SSTAR profile)
EntrezGene (mouse)	GeneID:18991 (SSTAR profile)
UniProt ID (human)	PO3F1_HUMAN
UniProt ID (mouse)	PO3F1_MOUSE
UniProt AC (human)	Q03052 (TFClass)
UniProt AC (mouse)	P21952 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 6 mouse
HT-SELEX	3
Methyl-HT-SELEX	1
Genomic HT-SELEX	0 overall: 0 Lysate, 0 IVT, 0 GFPIVT
SMiLE-Seq	0
PBM	0

PCM	PO3F1.H14INVIVO.2.S.C.pcm
PWM	PO3F1.H14INVIVO.2.S.C.pwm
PFM	PO3F1.H14INVIVO.2.S.C.pfm
Threshold to P-value map	PO3F1.H14INVIVO.2.S.C.thr
Motif in other formats
JASPAR format	PO3F1.H14INVIVO.2.S.C_jaspar_format.txt
MEME format	PO3F1.H14INVIVO.2.S.C_meme_format.meme
Transfac format	PO3F1.H14INVIVO.2.S.C_transfac_format.txt
Homer format	PO3F1.H14INVIVO.2.S.C_homer_format_0.001.txt PO3F1.H14INVIVO.2.S.C_homer_format_0.0005.txt PO3F1.H14INVIVO.2.S.C_homer_format_0.0001.txt

PCM

	A	C	G	T
01	2325.5	1842.5	2867.5	2363.5
02	14.0	45.0	43.0	9297.0
03	8687.0	0.0	712.0	0.0
04	9368.0	2.0	29.0	0.0
05	1.0	160.0	283.0	8955.0
06	23.0	0.0	3343.0	6033.0
07	7097.0	1160.0	464.0	678.0
08	2862.25	1463.25	4406.25	667.25
09	1569.0	3025.0	2615.0	2190.0

PFM

	A	C	G	T
01	0.247	0.196	0.305	0.251
02	0.001	0.005	0.005	0.989
03	0.924	0.0	0.076	0.0
04	0.997	0.0	0.003	0.0
05	0.0	0.017	0.03	0.953
06	0.002	0.0	0.356	0.642
07	0.755	0.123	0.049	0.072
08	0.305	0.156	0.469	0.071
09	0.167	0.322	0.278	0.233

PWM

	A	C	G	T
01	-0.01	-0.243	0.199	0.006
02	-4.973	-3.907	-3.95	1.375
03	1.307	-6.936	-1.192	-6.936
04	1.382	-6.307	-4.32	-6.936
05	-6.573	-2.674	-2.11	1.337
06	-4.533	-6.936	0.352	0.942
07	1.105	-0.705	-1.618	-1.241
08	0.197	-0.473	0.628	-1.256
09	-0.403	0.252	0.107	-0.07

Standard thresholds

P-value	Threshold
0.001	5.17008
0.0005	5.96333
0.0001	7.63749